布托啡诺与曲马多辅助局麻药治疗腋窝臂丛阻滞的比较

U. Bhatia, Gauri. M Panjabi, Atisha Patel
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引用次数: 1

摘要

背景随着阿片受体的出现,各种阿片药物被添加到用于外周阻滞的局部麻醉混合物中,以提高阻滞的质量和持续时间。在这项研究中,我们比较了布托啡诺和曲马多作为骨科上肢手术辅助剂的效果。患者和方法本研究选取50例年龄在18 ~ 60岁之间,美国麻醉师学会I级和II级,每组男女均可,均行上肢矫形手术经腋窝臂丛阻滞。局麻合剂中加入布托啡诺2 mg (B组)和曲马多100 mg (T组)。观察两组患者感觉和运动阻滞的发生情况、阻滞程度及并发症的发生情况。采用视觉模拟评分法观察患者术后镇痛情况。结果与T组(7.54±0.88和4.6±0.73)相比,B组感觉和运动阻滞的起效时间(min)分别延迟(8.76±1.0和5.86±0.71)。B组感觉阻滞持续时间(291.24±48.51 min)明显长于T组(160.42±12.66 min)。B组术后镇痛时间(首次抢救镇痛)为619.96±26.96 min, t组为290.2±20.38 min。结论布托啡诺比曲马多更有效,术后镇痛持续时间更长,具有镇静镇静的优势。
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Comparison of butorphanol and tramadol as an adjuvant to local anesthetic drug in axillary brachial plexus block
Background With the advent of opioid receptors, a variety of opioid agents are added to local anesthetic mixtures used in peripheral blocks to improve the quality and duration of block. In this study, we compared the effect of butorphanol and tramadol as adjuvant agents for orthopedic upper extremity surgery. Patients and methods This study was carried out on 50 patients aged between 18 and 60 years, of American Society of Anesthesiologists grades I and II, of either sexes in each group, undergoing orthopedic upper limb surgeries through axillary brachial plexus block. An injection of butorphanol 2 mg (group B) and that of tramadol 100 mg (group T) were added to local anesthetic mixture. Onset of sensory and motor blockade, extent of blockade, and occurrence of any complications were studied in both groups. All patients were observed for analgesia postoperatively by visual analog scale pain score. Results In our study, the onset time (minutes) of sensory and motor blockade was delayed in group B (8.76±1.0 and 5.86±0.71, respectively) as compared with group T (7.54±0.88 and 4.6±0.73, respectively). In group B, the duration of sensory block (291.24±48.51 min) was longer than group T (160.42±12.66 min). Duration of analgesia postoperatively (first rescue analgesic) was 619.96±26.96 min in group B, whereas it was 290.2±20.38 min in group T. Conclusion Butorphanol is more potent and produces longer duration of postoperative analgesia than tramadol, with an extra advantage of sedation and calmness.
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