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Intrathecal ketamine as an adjuvant in day-case surgeries: a reply for the comments on a previously published article 鞘内氯胺酮在日间手术中的辅助作用:对先前发表文章评论的回复
Pub Date : 2017-01-01 DOI: 10.4103/1687-7934.238470
M. Kamal, Dalia El-Fawy
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引用次数: 0
Postoperative outcome in major abdominal trauma: is the treatment of hypoalbuminemia beneficial? 重大腹部创伤的术后结局:低白蛋白血症的治疗是否有益?
Pub Date : 2017-01-01 DOI: 10.4103/1687-7934.238472
F. Ibrahim, Essam F. Abdelgalel
Background It had been suggested that the use of fluids containing albumin in critically ill patients may increase the absolute risk for death when compared with crystalloids. Objective The aim of this study was to compare the effect of albumin infusion versus conservative therapy on both serum albumin concentration (SAC) and patient outcome in case of postoperative hypoalbuminemia after exploration laparotomy for major abdominal trauma. Patients and methods Sixty-four patients with major abdominal trauma who had undergone exploration laparotomy were studied. In addition to patient’s demographic data, serial postoperative SAC and intra-abdominal pressure up to the seventh day were measured. Moreover, clinical, laboratory, and radiological follow-up was conducted to evaluate the morbidity until patient discharge from the hospital. The mortality rate was also recorded. Results There were no significant differences between patients who received albumin (group A) for the treatment of hypoalbuminemia and those who did not receive albumin (group B) as regards length of ICU stay (P=0.33), first postoperative day SAC (P=0.99), total complications (P=1), and individual postoperative complications [hemodynamic instability with vasopressor requirement (P=0.74), abdominal compartment syndrome (P=1), multiple organ dysfunction syndrome (P=1), and anastomotic leak (P=1), acute respiratory distress (P<0.6), and mortality (P=1)]. However, SAC was significantly higher on the third, fifth, and seventh day postoperatively in group A than in group B (P<0.001). Conclusion Postoperative treatment of hypoalbuminemia in major abdominal trauma had no benefit as regards morbidity and mortality.
研究背景:与晶体液体相比,在危重病人中使用含有白蛋白的液体可能会增加死亡的绝对风险。目的比较白蛋白输注与保守治疗对剖腹探查术后低白蛋白血症患者血清白蛋白浓度(SAC)和预后的影响。患者与方法对64例腹部外伤患者行探查式剖腹探查术进行分析。除了患者的人口统计数据外,还测量了连续的术后SAC和腹内压,直至第7天。此外,进行了临床、实验室和放射学随访,以评估患者的发病率,直到患者出院。死亡率也被记录下来。结果接受白蛋白治疗低白蛋白血症的患者(A组)与未接受白蛋白治疗的患者(B组)在ICU住院时间(P=0.33)、术后第1天SAC (P=0.99)、总并发症(P=1)和术后个体并发症[血管加压素需用血流动力学不稳定(P=0.74)、腹膜间室综合征(P=1)、多器官功能障碍综合征(P=1)、吻合口漏(P=1)]方面无显著差异。急性呼吸窘迫(P<0.6)和死亡率(P=1)。A组术后第3、5、7天SAC明显高于B组(P<0.001)。结论腹部重大外伤低白蛋白血症的术后治疗在发病率和死亡率方面均无明显优势。
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引用次数: 1
Effectiveness of minimal acute normovolemic hemodilution to minimize allogenic blood transfusion and re-exploration in elective adult coronary artery bypass graft surgery using colloid as a replacement solution 最小急性等容血液稀释以减少同种异体输血的有效性,并在选择性成人冠状动脉搭桥手术中使用胶体作为替代溶液
Pub Date : 2017-01-01 DOI: 10.4103/1687-7934.238460
M. Shorbagy, D. Salah
Background and aim Various studies have questioned the efficacy of intraoperative acute normovolemic hemodilution (ANH) in reducing bleeding, the need for allogenic transfusion, and the incidence of re-exploration in cardiac surgery. The aim of the present study was to evaluate the effectiveness of the use of minimal ANH for blood transfusion requirements and re-opening in elective adult coronary artery bypass graft surgery using cardiopulmonary bypass. Patients and methods This prospective, randomized controlled study was conducted on 100 consecutive adult patients who underwent elective coronary artery bypass graft. Patients were randomly divided into two equal groups: the ANH group (n=50) and the control group (n=50). In the ANH group, 5–8 ml/kg of autologous blood was withdrawn after administering anesthesia and before systemic heparinization. Simultaneously, colloid solution (6% hydroxyethyl starch 130/0.4; Voluven) was infused in a ratio of 1:1, and then the blood was re-infused after bypass. Hemodilation was not carried out for the control group. Total amount of allogenic-packed red blood cell, fresh frozen plasma, platelet concentrate transfusion, and the number of patients undergoing re-opening because of excessive bleeding were calculated for the two groups. Results A significant decrease was observed in the number of red blood cell units and fresh frozen plasma transfusion per patient in the ANH group compared with the control group. Conversely, chest tube output, representing postoperative bleeding and platelet count, did not differ between the two groups. Conclusion In this study, the use of the minimal ANH technique reduced the consumption of allogenic red blood cells and fresh frozen plasma in adult cardiac surgery patients. However, this technique had no effect on postoperative bleeding, incidence of re-exploration, and platelet count.
背景与目的各种研究都质疑术中急性等容血液稀释(ANH)在减少出血方面的疗效、异体输血的必要性以及心脏手术中再次探查的发生率。本研究的目的是评估在选择性成人冠状动脉搭桥手术中使用最小ANH进行输血和再开放的有效性。患者和方法本前瞻性、随机对照研究对连续100例接受择期冠状动脉旁路移植术的成年患者进行了研究。将患者随机分为两组:ANH组(n=50)和对照组(n=50)。ANH组在麻醉后和全身肝素化前取5-8 ml/kg的自体血。同时,胶体溶液(6%羟乙基淀粉130/0.4;按1:1的比例输注Voluven,旁路后再输注。对照组不进行血液扩张。计算两组异体填充红细胞、新鲜冷冻血浆、浓缩血小板输注总量和因出血过多而重新开放的患者人数。结果与对照组相比,ANH组患者红细胞单位数和新鲜冷冻血浆输注数均显著降低。相反,代表术后出血和血小板计数的胸管输出量在两组之间没有差异。结论在本研究中,使用最小ANH技术可以减少成人心脏手术患者的同种异体红细胞和新鲜冷冻血浆的消耗。然而,该技术对术后出血、再探查发生率和血小板计数没有影响。
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引用次数: 0
Intrathecal hyperbaric bupivacaine with fentanyl for labor pain control: a comparative study with continuous epidural analgesia with bupivacaine 芬太尼加布比卡因鞘内高压镇痛与布比卡因硬膜外持续镇痛的比较研究
Pub Date : 2017-01-01 DOI: 10.4103/1687-7934.238463
M. Younes, K. Gamil, A. Elgarhy
Objective The aim of the study was to assess single-dose intrathecal bupivacaine in combination with fentanyl as a safe and effective alternative to epidural for labor analgesia. Patients and methods Sixty women aged 20–30 years, of American Society of Anesthesiology I–II, and with a single uncomplicated pregnancy were included in this study. Patients were randomly allocated to two equal groups: the spinal group received hyperbaric bupivacaine 0.5% at a dose of 1 ml plus 25 μg fentanyl (0.5 ml), whereas the epidural group received bupivacaine 0.25% at a 14 ml bolus dose with a background epidural infusion of bupivacaine 0.125% at 10 ml/h. Pain intensity was recorded on a visual analogue scale. The quality of pain relief was also related to patient satisfaction after delivery. Side effects such as hypotension, motor block, pruritus, sedation, and nausea were noted. Obstetric parameters and Apgar score were noted, and all results were compared. Results Onset of sensory block was earlier (5.6 ± 1.27 vs. 8.8 ± 1.62 min, P < 0.001) and visual analogue scale at 5, 60, 90, 120, and 150 min was lower in the spinal group compared with the epidural group. All these results were statistically signifi cant. Ninety percent of the parturients in the spinal group versus 62% in the epidural group scored the analgesic quality as excellent. No significant hemodynamic changes were recorded in either group. There were no significant differences between the two groups in motor block, sedation, and nausea. No cesarean section or instrumental delivery was performed. Oxytocin augmentation was needed in 33.3 versus 50% of the parturients in the spinal and epidural groups, respectively. Fetal heart rate disturbances were seen in 10% in the epidural group versus 6.6% in the spinal group. Apgar scores were high and no neonate had Apgar score less than 7 in either group. The overall cost was lower in the spinal group compared with the epidural group. Conclusion Single-dose intrathecal local anesthetic with narcotics is shown to relieve pain safely in most laboring women, with rapid onset and prolonged duration of labor analgesia comparable to that of epidural analgesia while being more easily performed, less time-consuming, and less expensive, and providing similarly excellent analgesia.
目的评价单剂量布比卡因联合芬太尼作为硬膜外分娩镇痛的安全有效替代方案。患者和方法入选美国麻醉学学会I-II分会,年龄20-30岁,单次无并发症妊娠的女性60例。患者被随机分为两组:脊柱组接受0.5%布比卡因高压治疗,剂量为1 ml,加25 μg芬太尼(0.5 ml),而硬膜外组接受0.25%布比卡因,剂量为14 ml,硬膜外背景输注0.125%布比卡因,剂量为10 ml/h。用视觉模拟量表记录疼痛强度。分娩后疼痛缓解的质量也与患者满意度有关。副作用如低血压、运动阻滞、瘙痒、镇静和恶心。记录产科参数和Apgar评分,并对所有结果进行比较。结果脊髓组感觉阻滞发生时间较硬膜外组早(5.6±1.27 vs 8.8±1.62 min, P < 0.001), 5、60、90、120、150 min的视觉模拟评分较硬膜外组低。这些结果均有统计学意义。脊髓组90%的产妇和硬膜外组62%的产妇认为镇痛质量优良。两组均未见明显血流动力学变化。两组在运动阻滞、镇静和恶心方面无显著差异。未进行剖宫产或器械分娩。脊髓组和硬膜外组分别有33.3%和50%的产妇需要催产素增强。硬膜外麻醉组胎儿心率紊乱发生率为10%,脊髓麻醉组为6.6%。两组新生儿Apgar评分均较高,均未低于7分。与硬膜外组相比,脊髓组的总成本较低。结论单剂量鞘内局麻加麻醉品可安全缓解大多数产妇的疼痛,与硬膜外镇痛相比,分娩镇痛起效快、持续时间长,且操作简单、耗时短、费用低,镇痛效果同样优异。
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引用次数: 2
Effect of preoperative pregabalin versus gabapentin on postoperative pain control after laparoscopic gastric bypass surgery 术前普瑞巴林与加巴喷丁对腹腔镜胃旁路手术术后疼痛控制的影响
Pub Date : 2017-01-01 DOI: 10.4103/asja.asja_21_16
Khalid Abd El-Maksoud, M. Younes, Sherif A. Elokda
© 2018 Ain-Shams Journal of Anaesthesiology | Publishe Background Perioperative gabapentin helps produce a significant opioid-sparing effect and probably also improves postoperative pain scores. Pregabalin is a novel drug with a heightened research interest in the analgesic, sedative, anxiolytic, and opioidsparingeffects, invariouspainsettings, includingpostoperativepain.We investigated pregabalin analgesic efficacy in morbid obese patients experiencing acute pain after laparoscopic gastric bypass surgery and compared it with gabapentin and placebo. Patients and methods A randomized, placebo-controlled study was conducted on 90 morbidly obese patients undergoing laparoscopic gastric bypass surgery. Patients were allocated into one of the three groups; the pregabalin group in which the patients received 300mg pregabalin, the gabapentin group in which the patients received 1200mg gabapentin, or the control group in which the patients received placebo 2h prior to surgery. Postoperative pain was controlled with intravenous fentanyl via patient controlled analgesia (PCA). Fentanyl consumption over 24 h and pain intensity measured by visual analogue score at rest (static) and during cough (dynamic) at recovery time, 1, 2, 6, 12, and 24h were recorded. Also sedation status, somnolence, dizziness, headache, nausea, and vomiting were monitored. Results Postoperative 24 h fentanyl consumption was significantly higher in the control group compared with both pregabalin and gabapentin groups (P<0.001). Pain intensity on visual analogue score (static and dynamic) was significantly higher in the control group compared with both pregabalin and gabapentin groups at time of recovery, 1, 2, 6, 12, and 24 h postoperatively. Numeric sedation score was significantly lower in the control group compared with pregabalin and gabapentin groups at time of recovery, 1, 2, and 6h postoperatively. No significant differences were found among the three groups as regards somnolence, dizziness, headache, nausea, and vomiting. Conclusion A single dose of 300mg pregabalin or 1200mg gabapentin given 2 h before surgery is better than placebo for postoperative pain control for laparoscopic gastric bypass surgery without significant side effects.
©2018 Ain-Shams麻醉学杂志|出版背景围手术期加巴喷丁有助于产生显著的阿片类药物节约效果,也可能改善术后疼痛评分。普瑞巴林是一种新型药物,在镇痛、镇静、抗焦虑和阿片类药物保护作用方面具有很高的研究兴趣,在各种情况下,包括术后疼痛。我们研究了普瑞巴林在腹腔镜胃旁路手术后急性疼痛的病态肥胖患者中的镇痛效果,并将其与加巴喷丁和安慰剂进行了比较。患者和方法对90例接受腹腔镜胃旁路手术的病态肥胖患者进行随机、安慰剂对照研究。患者被分为三组之一;普瑞巴林组患者接受300mg普瑞巴林,加巴喷丁组患者接受1200mg加巴喷丁,或对照组患者在手术前2h接受安慰剂。术后通过患者自控镇痛(PCA)静脉注射芬太尼控制疼痛。记录24h内芬太尼用量及恢复时间(1、2、6、12、24h)静息(静态)和咳嗽(动态)时视觉模拟评分测量疼痛强度。同时监测镇静状态、嗜睡、头晕、头痛、恶心和呕吐。结果对照组术后24 h芬太尼用量明显高于普瑞巴林组和加巴喷丁组(P<0.001)。恢复时、术后1、2、6、12、24 h,对照组视觉模拟评分(静态和动态)疼痛强度均显著高于普瑞巴林组和加巴喷丁组。在恢复时、术后1、2、6h,对照组的数值镇静评分明显低于普瑞巴林组和加巴喷丁组。三组患者在嗜睡、头晕、头痛、恶心和呕吐方面无显著差异。结论术前2 h单剂量普瑞巴林300mg或加巴喷丁1200mg对腹腔镜胃旁路手术术后疼痛的控制效果优于安慰剂,且无明显副作用。
{"title":"Effect of preoperative pregabalin versus gabapentin on postoperative pain control after laparoscopic gastric bypass surgery","authors":"Khalid Abd El-Maksoud, M. Younes, Sherif A. Elokda","doi":"10.4103/asja.asja_21_16","DOIUrl":"https://doi.org/10.4103/asja.asja_21_16","url":null,"abstract":"© 2018 Ain-Shams Journal of Anaesthesiology | Publishe Background Perioperative gabapentin helps produce a significant opioid-sparing effect and probably also improves postoperative pain scores. Pregabalin is a novel drug with a heightened research interest in the analgesic, sedative, anxiolytic, and opioidsparingeffects, invariouspainsettings, includingpostoperativepain.We investigated pregabalin analgesic efficacy in morbid obese patients experiencing acute pain after laparoscopic gastric bypass surgery and compared it with gabapentin and placebo. Patients and methods A randomized, placebo-controlled study was conducted on 90 morbidly obese patients undergoing laparoscopic gastric bypass surgery. Patients were allocated into one of the three groups; the pregabalin group in which the patients received 300mg pregabalin, the gabapentin group in which the patients received 1200mg gabapentin, or the control group in which the patients received placebo 2h prior to surgery. Postoperative pain was controlled with intravenous fentanyl via patient controlled analgesia (PCA). Fentanyl consumption over 24 h and pain intensity measured by visual analogue score at rest (static) and during cough (dynamic) at recovery time, 1, 2, 6, 12, and 24h were recorded. Also sedation status, somnolence, dizziness, headache, nausea, and vomiting were monitored. Results Postoperative 24 h fentanyl consumption was significantly higher in the control group compared with both pregabalin and gabapentin groups (P<0.001). Pain intensity on visual analogue score (static and dynamic) was significantly higher in the control group compared with both pregabalin and gabapentin groups at time of recovery, 1, 2, 6, 12, and 24 h postoperatively. Numeric sedation score was significantly lower in the control group compared with pregabalin and gabapentin groups at time of recovery, 1, 2, and 6h postoperatively. No significant differences were found among the three groups as regards somnolence, dizziness, headache, nausea, and vomiting. Conclusion A single dose of 300mg pregabalin or 1200mg gabapentin given 2 h before surgery is better than placebo for postoperative pain control for laparoscopic gastric bypass surgery without significant side effects.","PeriodicalId":7492,"journal":{"name":"Ain-Shams Journal of Anaesthesiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86655101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Controlled hypotension for functional endoscopic sinus surgery: a Comparative study between magnesium sulfate and nitroglycerin 功能性内窥镜鼻窦手术控制低血压:硫酸镁与硝酸甘油的比较研究
Pub Date : 2017-01-01 DOI: 10.4103/asja.asja_46_16
R. Shoukry, A. Mahmoud
Background Intraoperative bleeding during functional endoscopic sinus surgery (FESS) leads to poor visibility of the surgical field, and is of major concern. Controlled hypotension, using a variety of pharmacological agents, during general anesthesia reduces blood loss and helps clear visibility of the surgical field during FESS. The aim of this study was to compare the surgical conditions for FESS during controlled hypotension provided by nitroglycerin (NTG) versus magnesium sulfate (MGS) under general anesthesia. Patients and methods Fifty adult patients of both sexes requiring FESS under general anesthesia were randomly divided to receive either NTG infusion of 3–5 µg/kg/min (group NTG, n=25) or MGS (group MGS, n=25) 30 mg/kg, administered as a slow intravenous bolus and 10 mg/kg/h by continuous infusion during the operation, to provide controlled hypotension. In both the groups, the mean arterial blood pressure was reduced until the targeted mean arterial blood pressure (55–65 mmHg) was achieved. Results Both drugs produced the desired hypotension, in the magnesium group there were better operative conditions, reduction in the duration of surgery (85.3±13.1 vs. 92.9±10.3 min) and reduced anesthetic requirements [average end-tidal sevoflurane concentration (vol %) and fentanyl consumption (μg); P<0.0001]. However, there was longer extubation time (10.0±2.9 vs. 5.5±2.3 min) and recovery time (16.7±4.4 vs. 9.8±2.3 min) in comparison with the NTG group. Heart rate values were significantly higher in the NTG group compared with the magnesium group (P<0.0004). Conclusion Both NTG and MGS can be used safely to provide controlled hypotension during FESS. However, MGS was better as it provided optimum surgical condition and less tachycardia. In addition, it led to decreased anesthetic requirements.
背景:功能性内窥镜鼻窦手术(FESS)术中出血导致手术视野不清晰,是一个主要的问题。在全身麻醉期间,使用多种药物控制低血压,减少失血,并有助于在FESS期间清晰手术视野。本研究的目的是比较全身麻醉下硝酸甘油(NTG)和硫酸镁(MGS)提供的控制性低血压期间FESS的手术条件。患者和方法50例需要全麻FESS的成年患者,随机分为两组,分别给予3-5µg/kg/min的NTG (NTG组,n=25)和30 mg/kg的MGS (MGS组,n=25),术中缓慢静脉滴注,10 mg/kg/h,持续滴注,以控制低血压。在两组中,平均动脉血压都有所降低,直到达到目标平均动脉血压(55-65 mmHg)。结果两种药物均达到预期降压效果,镁组手术条件较好,手术时间缩短(85.3±13.1 vs 92.9±10.3 min),麻醉需用量[平均潮末七氟醚浓度(vol %)和芬太尼用量(μg)]减少;P < 0.0001)。但拔管时间(10.0±2.9 vs. 5.5±2.3 min)和恢复时间(16.7±4.4 vs. 9.8±2.3 min)较NTG组明显延长。NTG组心率值显著高于镁组(P<0.0004)。结论NTG和MGS均可安全用于FESS术中控制性降压。然而,MGS的效果更好,因为它提供了最佳的手术条件和较少的心动过速。此外,它还减少了麻醉需求。
{"title":"Controlled hypotension for functional endoscopic sinus surgery: a Comparative study between magnesium sulfate and nitroglycerin","authors":"R. Shoukry, A. Mahmoud","doi":"10.4103/asja.asja_46_16","DOIUrl":"https://doi.org/10.4103/asja.asja_46_16","url":null,"abstract":"Background Intraoperative bleeding during functional endoscopic sinus surgery (FESS) leads to poor visibility of the surgical field, and is of major concern. Controlled hypotension, using a variety of pharmacological agents, during general anesthesia reduces blood loss and helps clear visibility of the surgical field during FESS. The aim of this study was to compare the surgical conditions for FESS during controlled hypotension provided by nitroglycerin (NTG) versus magnesium sulfate (MGS) under general anesthesia. Patients and methods Fifty adult patients of both sexes requiring FESS under general anesthesia were randomly divided to receive either NTG infusion of 3–5 µg/kg/min (group NTG, n=25) or MGS (group MGS, n=25) 30 mg/kg, administered as a slow intravenous bolus and 10 mg/kg/h by continuous infusion during the operation, to provide controlled hypotension. In both the groups, the mean arterial blood pressure was reduced until the targeted mean arterial blood pressure (55–65 mmHg) was achieved. Results Both drugs produced the desired hypotension, in the magnesium group there were better operative conditions, reduction in the duration of surgery (85.3±13.1 vs. 92.9±10.3 min) and reduced anesthetic requirements [average end-tidal sevoflurane concentration (vol %) and fentanyl consumption (μg); P<0.0001]. However, there was longer extubation time (10.0±2.9 vs. 5.5±2.3 min) and recovery time (16.7±4.4 vs. 9.8±2.3 min) in comparison with the NTG group. Heart rate values were significantly higher in the NTG group compared with the magnesium group (P<0.0004). Conclusion Both NTG and MGS can be used safely to provide controlled hypotension during FESS. However, MGS was better as it provided optimum surgical condition and less tachycardia. In addition, it led to decreased anesthetic requirements.","PeriodicalId":7492,"journal":{"name":"Ain-Shams Journal of Anaesthesiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89443314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
The efficacy of rectus sheath block for pain management following laparoscopic orchiopexy surgery 直肌鞘阻滞治疗腹腔镜睾丸切除术后疼痛的疗效
Pub Date : 2017-01-01 DOI: 10.4103/1687-7934.238459
Hoda Shokri
Background Ultrasound (U/S)-guided rectus sheath block is an effective analgesic technique in elective pediatric laparoscopic surgical procedures. The aim of the study was to evaluate the efficacy of rectus sheath block for pain management following laparoscopic orchiopexy surgery. Patients and methods A total of 50 patients undergoing elective laparoscopic orchiopexy were allocated randomly into two groups: the U/S-guided rectus sheath block group (the REC group) and the general anesthesia-only group (the GA group), in which no rectus sheath block was performed. All patients received the same general anesthetic technique. In the REC group, patients received bilateral U/S-guided rectus sheath block, using 0.4 ml/kg of 0.25% bupivacaine, and morphine (0.1 mg/kg) was administered for rescue analgesia postoperatively and its total dose was recorded. Pain was measured by means of Children’s Hospital of Eastern Ontario Pain Scale score. Hospital stay and the incidence of respiratory depression or vomiting were recorded. Results In all, 50 patients completed the study. The total dose of morphine used over 24 h was significantly lower in the REC group. Children’s Hospital of Eastern Ontario Pain Scale scores were significantly lower in the REC group during the first 3 h postoperatively, and the incidence of vomiting, respiratory depression, and oxygen saturation in the postanesthesia care unit showed no significant difference between the study groups. Hospital stay was significantly shorter in the REC group compared with the GA group. Conclusion U/S-guided rectus sheath block is an effective analgesic technique with morphine-sparing effect after laparoscopic orchiopexy surgery.
背景超声(U/S)引导下的直肌鞘阻滞是一种有效的儿科腹腔镜手术镇痛技术。本研究的目的是评估直肌鞘阻滞对腹腔镜睾丸切除术后疼痛管理的疗效。患者与方法选择50例择期腹腔镜睾丸切除术患者,随机分为U/ s引导下直肌鞘阻滞组(REC组)和仅全身麻醉组(GA组),其中不进行直肌鞘阻滞。所有患者均接受相同的全身麻醉技术。REC组患者接受双侧U/ s引导下的直肌鞘阻滞,术后给予0.25%布比卡因0.4 ml/kg,吗啡(0.1 mg/kg)进行抢救镇痛,并记录总剂量。疼痛采用东安大略儿童医院疼痛量表评分。记录住院时间和呼吸抑制或呕吐的发生率。结果总共有50名患者完成了研究。REC组24 h吗啡总剂量明显降低。东安大略儿童医院疼痛量表评分在术后前3小时REC组明显较低,麻醉后护理单元呕吐、呼吸抑制和血氧饱和度的发生率在研究组之间无显著差异。与GA组相比,REC组住院时间明显缩短。结论U/ s引导下直肌鞘阻滞是一种有效的腹腔镜睾丸切除术后镇痛技术,具有节约吗啡的效果。
{"title":"The efficacy of rectus sheath block for pain management following laparoscopic orchiopexy surgery","authors":"Hoda Shokri","doi":"10.4103/1687-7934.238459","DOIUrl":"https://doi.org/10.4103/1687-7934.238459","url":null,"abstract":"Background Ultrasound (U/S)-guided rectus sheath block is an effective analgesic technique in elective pediatric laparoscopic surgical procedures. The aim of the study was to evaluate the efficacy of rectus sheath block for pain management following laparoscopic orchiopexy surgery. Patients and methods A total of 50 patients undergoing elective laparoscopic orchiopexy were allocated randomly into two groups: the U/S-guided rectus sheath block group (the REC group) and the general anesthesia-only group (the GA group), in which no rectus sheath block was performed. All patients received the same general anesthetic technique. In the REC group, patients received bilateral U/S-guided rectus sheath block, using 0.4 ml/kg of 0.25% bupivacaine, and morphine (0.1 mg/kg) was administered for rescue analgesia postoperatively and its total dose was recorded. Pain was measured by means of Children’s Hospital of Eastern Ontario Pain Scale score. Hospital stay and the incidence of respiratory depression or vomiting were recorded. Results In all, 50 patients completed the study. The total dose of morphine used over 24 h was significantly lower in the REC group. Children’s Hospital of Eastern Ontario Pain Scale scores were significantly lower in the REC group during the first 3 h postoperatively, and the incidence of vomiting, respiratory depression, and oxygen saturation in the postanesthesia care unit showed no significant difference between the study groups. Hospital stay was significantly shorter in the REC group compared with the GA group. Conclusion U/S-guided rectus sheath block is an effective analgesic technique with morphine-sparing effect after laparoscopic orchiopexy surgery.","PeriodicalId":7492,"journal":{"name":"Ain-Shams Journal of Anaesthesiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79520987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Comparative study between ultrasound-guided thoracic paravertebral nerve block and intraperitoneal instillation of local anesthetic as pre-emptive analgesia in laparoscopic cholecystectomy surgery 超声引导下胸椎旁神经阻滞与腹腔内注入局麻在腹腔镜胆囊切除术中先发制人镇痛的比较研究
Pub Date : 2017-01-01 DOI: 10.4103/asja.asja_126_16
Asmaa Abdellah, Fatma Ashour, Enas Elshanawany
Background Thoracic paravertebral block (TPVB) is an effective technique in controlling pain after lower thoracic and upper abdominal surgery, and ultrasound guidance is a recent technique that may offer several advantages. Intraperitoneal injections of local anesthetics have been proposed to minimize postoperative pain after laparoscopic surgery. Patients and methods A total of 60 patients with American Society of Anesthesiologists status I and II aged 30–50 years undergoing elective laparoscopic cholecystectomy were divided into three equal groups (20 patients each): ultrasound-guided thoracic paravertebral block (UG-TPVB group) with 20 ml 0.25% bupivacaine bilaterally, intraperitoneal instillation of local anesthetics with 50 ml 0.25% bupivacaine after inflation of the abdomen with gas (IP group), and general anesthesia alone without any local anesthetics (GA group) (control group). General anesthesia was induced for all patients. Intraoperative and postoperative hemodynamic data (mean arterial blood pressure and heart rate) were recorded. Intraoperative anesthetic and analgesic consumption, pain intensity using visual analog scale, pethidine consumption, serum cortisol, blood glucose level, and complications were estimated. Results Hemodynamic data were significantly lower in IP and UG-TPVB groups compared with GA group (P<0.05), and on comparing UG-TPVB group with IP group, with no significant difference was seen regarding postanaesthesia care unit admission and discharge (P1>0.05). End-tidal sevoflurane % (UG-TPVB: 1.1±0.21, IP: 1.8±0.22, GA: 2±0.23) and volume of consumption (UG-TPVB: 12.0±0.9, IP: 15.1±0.7, GA: 18.2±2) showed significant decrease when comparing UG-TPVB and IP groups with GA group (P<0.05). The mean dose of intraoperative fentanyl, mean dose of postoperative pethidine consumption, and the number of patients who received pethidine were significantly lower in IP and UG-TPVB groups compared with GA group (P<0.05). Postoperative serum cortisol and blood glucose level showed significant decrease in UG-TPVB and IP groups compared with GA group at 6 and 24 h postoperative (P<0.05). Pain score using visual analog scale and number of patients who experienced postoperative nausea and vomiting were significantly decreased in both groups in comparison with GA group. Conclusion UG-TPVB and IP bupivacaine instillation as pre-emptive analgesia in laparoscopic cholecystectomy provided good intraoperative and postoperative analgesia and decreased the dose of anesthetics used with great safety, and the incidence of complications was less.
胸椎旁阻滞(TPVB)是一种有效的技术,可以控制下胸部和上腹部手术后的疼痛,超声引导是一种最新的技术,可以提供几个优势。腹腔注射局麻药已被建议减少腹腔镜手术后的疼痛。患者和方法选取年龄30 ~ 50岁,美国麻醉医师学会认证I、II级的择期腹腔镜胆囊切除术患者60例,随机分为3组,每组20例:超声引导下胸椎旁阻滞(UG-TPVB组)双侧给予0.25%布比卡因20ml,腹部充气后腹腔内滴注0.25%布比卡因50ml局麻药(IP组),全麻不加局麻药(GA组)(对照组)。所有患者均行全身麻醉。记录术中和术后血流动力学数据(平均动脉血压和心率)。评估术中麻醉镇痛药用量、疼痛强度(视觉模拟量表)、哌啶用量、血清皮质醇、血糖水平及并发症。结果与GA组相比,IP组和UG-TPVB组血流动力学指标明显降低(P0.05)。末潮七氟烷% (UG-TPVB: 1.1±0.21,IP: 1.8±0.22,GA: 2±0.23)和消耗量(UG-TPVB: 12.0±0.9,IP: 15.1±0.7,GA: 18.2±2)与GA组比较,UG-TPVB组和IP组显著降低(P<0.05)。IP组和UG-TPVB组术中芬太尼平均剂量、术后哌啶平均消耗剂量、哌啶用药人数均显著低于GA组(P<0.05)。UG-TPVB组和IP组术后6、24h血清皮质醇、血糖水平均显著低于GA组(P<0.05)。与GA组比较,两组术后疼痛评分及恶心呕吐患者数均明显减少。结论采用UG-TPVB和IP布比卡因灌注作为腹腔镜胆囊切除术的先发制人镇痛,术中术后镇痛效果好,减少了麻醉剂用量,安全性好,并发症发生率低。
{"title":"Comparative study between ultrasound-guided thoracic paravertebral nerve block and intraperitoneal instillation of local anesthetic as pre-emptive analgesia in laparoscopic cholecystectomy surgery","authors":"Asmaa Abdellah, Fatma Ashour, Enas Elshanawany","doi":"10.4103/asja.asja_126_16","DOIUrl":"https://doi.org/10.4103/asja.asja_126_16","url":null,"abstract":"Background Thoracic paravertebral block (TPVB) is an effective technique in controlling pain after lower thoracic and upper abdominal surgery, and ultrasound guidance is a recent technique that may offer several advantages. Intraperitoneal injections of local anesthetics have been proposed to minimize postoperative pain after laparoscopic surgery. Patients and methods A total of 60 patients with American Society of Anesthesiologists status I and II aged 30–50 years undergoing elective laparoscopic cholecystectomy were divided into three equal groups (20 patients each): ultrasound-guided thoracic paravertebral block (UG-TPVB group) with 20 ml 0.25% bupivacaine bilaterally, intraperitoneal instillation of local anesthetics with 50 ml 0.25% bupivacaine after inflation of the abdomen with gas (IP group), and general anesthesia alone without any local anesthetics (GA group) (control group). General anesthesia was induced for all patients. Intraoperative and postoperative hemodynamic data (mean arterial blood pressure and heart rate) were recorded. Intraoperative anesthetic and analgesic consumption, pain intensity using visual analog scale, pethidine consumption, serum cortisol, blood glucose level, and complications were estimated. Results Hemodynamic data were significantly lower in IP and UG-TPVB groups compared with GA group (P<0.05), and on comparing UG-TPVB group with IP group, with no significant difference was seen regarding postanaesthesia care unit admission and discharge (P1>0.05). End-tidal sevoflurane % (UG-TPVB: 1.1±0.21, IP: 1.8±0.22, GA: 2±0.23) and volume of consumption (UG-TPVB: 12.0±0.9, IP: 15.1±0.7, GA: 18.2±2) showed significant decrease when comparing UG-TPVB and IP groups with GA group (P<0.05). The mean dose of intraoperative fentanyl, mean dose of postoperative pethidine consumption, and the number of patients who received pethidine were significantly lower in IP and UG-TPVB groups compared with GA group (P<0.05). Postoperative serum cortisol and blood glucose level showed significant decrease in UG-TPVB and IP groups compared with GA group at 6 and 24 h postoperative (P<0.05). Pain score using visual analog scale and number of patients who experienced postoperative nausea and vomiting were significantly decreased in both groups in comparison with GA group. Conclusion UG-TPVB and IP bupivacaine instillation as pre-emptive analgesia in laparoscopic cholecystectomy provided good intraoperative and postoperative analgesia and decreased the dose of anesthetics used with great safety, and the incidence of complications was less.","PeriodicalId":7492,"journal":{"name":"Ain-Shams Journal of Anaesthesiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80411072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Propofol, remifentanil, and low-dose atracurium besylate versus sevoflurane and fentanyl for bronchoscopy in children: a randomized-controlled trial 异丙酚、瑞芬太尼和低剂量苯磺酸阿曲库铵与七氟醚和芬太尼用于儿童支气管镜检查:一项随机对照试验
Pub Date : 2017-01-01 DOI: 10.4103/1687-7934.238452
A. Kasem, F. Elbokl, H. Elzahaby, Hisham Elazzazy, A. Elsayed
Objective The aim of this study was to compare the use of remifentanil and propofol infusion plus low-dose atracurium besylate technique with the commonly used inhalational technique using sevoflurane with fentanyl for children undergoing bronchoscopy for foreign body (FB) removal. Patients and methods This prospective randomized-controlled trial was conducted at Ain Shams University Hospitals. Sixty children aged 1–5 years planned for elective or emergency FB removal by bronchoscopy were included in the current study. The recruited children were assigned randomly into two groups: group I: total intravenous anesthesia (TIVA group) (remifentanil, propofol, and low-dose atracurium besylate); group II: volatile induction and maintenance of anesthesia (VIMA) (sevoflurane and fentanyl). Intraoperative and postoperative measurements and complications were recorded. Results There was no statistically significant difference between both groups in induction time, bronchoscopy time, time for discharge from the recovery room, and emergence time between both groups. The number of bronchoscopy attempts, interruptions of bronchoscopy, and body movements were significantly higher in the VIMA group than the TIVA group; satisfaction with surgery was greater in the TIVA group than the VIMA group. There was no difference between groups in the incidence of complications, except for postoperative agitation, with a higher incidence in the VIMA group compared with the TIVA group. Conclusion The use of 0.1 µg/kg/min remifentanil-propofol TIVA, plus a small dose (0.25 mg/kg) of atracurium besylate at induction, provided stable hemodynamics, better surgeon satisfaction, and less postoperative agitation compared with sevoflurane 2% in 100% oxygen plus fentanyl 1 µg/kg in children undergoing tracheobronchial FB removal during rigid bronchoscopy.
目的比较瑞芬太尼和异丙酚输注加小剂量苯磺酸阿曲库铵技术与常用的七氟醚和芬太尼吸入技术在儿童支气管镜异物取出术中的应用。患者和方法本前瞻性随机对照试验在艾因沙姆斯大学医院进行。本研究纳入了60名1-5岁的儿童,他们计划通过支气管镜选择性或紧急切除FB。招募的儿童随机分为两组:第一组:全静脉麻醉(TIVA组)(瑞芬太尼、异丙酚和低剂量苯磺酸阿曲库铵);II组:挥发性诱导和维持麻醉(VIMA)(七氟醚和芬太尼)。记录术中、术后测量及并发症。结果两组患者的诱导时间、支气管镜检查时间、出院时间、急诊时间比较,差异均无统计学意义。VIMA组的支气管镜检查尝试次数、支气管镜检查中断次数和身体运动次数明显高于TIVA组;TIVA组手术满意度高于VIMA组。除术后躁动外,各组间并发症的发生率无差异,VIMA组的发生率高于TIVA组。结论使用0.1µg/kg/min瑞芬太尼-异丙酚TIVA,在诱导时加小剂量(0.25 mg/kg)的苯甲酸阿曲库铵,与七氟醚2%、100%氧加芬太尼1µg/kg相比,可提供稳定的血流动力学,更好的外科医生满意度和更少的术后激动。
{"title":"Propofol, remifentanil, and low-dose atracurium besylate versus sevoflurane and fentanyl for bronchoscopy in children: a randomized-controlled trial","authors":"A. Kasem, F. Elbokl, H. Elzahaby, Hisham Elazzazy, A. Elsayed","doi":"10.4103/1687-7934.238452","DOIUrl":"https://doi.org/10.4103/1687-7934.238452","url":null,"abstract":"Objective The aim of this study was to compare the use of remifentanil and propofol infusion plus low-dose atracurium besylate technique with the commonly used inhalational technique using sevoflurane with fentanyl for children undergoing bronchoscopy for foreign body (FB) removal. Patients and methods This prospective randomized-controlled trial was conducted at Ain Shams University Hospitals. Sixty children aged 1–5 years planned for elective or emergency FB removal by bronchoscopy were included in the current study. The recruited children were assigned randomly into two groups: group I: total intravenous anesthesia (TIVA group) (remifentanil, propofol, and low-dose atracurium besylate); group II: volatile induction and maintenance of anesthesia (VIMA) (sevoflurane and fentanyl). Intraoperative and postoperative measurements and complications were recorded. Results There was no statistically significant difference between both groups in induction time, bronchoscopy time, time for discharge from the recovery room, and emergence time between both groups. The number of bronchoscopy attempts, interruptions of bronchoscopy, and body movements were significantly higher in the VIMA group than the TIVA group; satisfaction with surgery was greater in the TIVA group than the VIMA group. There was no difference between groups in the incidence of complications, except for postoperative agitation, with a higher incidence in the VIMA group compared with the TIVA group. Conclusion The use of 0.1 µg/kg/min remifentanil-propofol TIVA, plus a small dose (0.25 mg/kg) of atracurium besylate at induction, provided stable hemodynamics, better surgeon satisfaction, and less postoperative agitation compared with sevoflurane 2% in 100% oxygen plus fentanyl 1 µg/kg in children undergoing tracheobronchial FB removal during rigid bronchoscopy.","PeriodicalId":7492,"journal":{"name":"Ain-Shams Journal of Anaesthesiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90730150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of butorphanol and tramadol as an adjuvant to local anesthetic drug in axillary brachial plexus block 布托啡诺与曲马多辅助局麻药治疗腋窝臂丛阻滞的比较
Pub Date : 2017-01-01 DOI: 10.4103/asja.asja_51_16
U. Bhatia, Gauri. M Panjabi, Atisha Patel
Background With the advent of opioid receptors, a variety of opioid agents are added to local anesthetic mixtures used in peripheral blocks to improve the quality and duration of block. In this study, we compared the effect of butorphanol and tramadol as adjuvant agents for orthopedic upper extremity surgery. Patients and methods This study was carried out on 50 patients aged between 18 and 60 years, of American Society of Anesthesiologists grades I and II, of either sexes in each group, undergoing orthopedic upper limb surgeries through axillary brachial plexus block. An injection of butorphanol 2 mg (group B) and that of tramadol 100 mg (group T) were added to local anesthetic mixture. Onset of sensory and motor blockade, extent of blockade, and occurrence of any complications were studied in both groups. All patients were observed for analgesia postoperatively by visual analog scale pain score. Results In our study, the onset time (minutes) of sensory and motor blockade was delayed in group B (8.76±1.0 and 5.86±0.71, respectively) as compared with group T (7.54±0.88 and 4.6±0.73, respectively). In group B, the duration of sensory block (291.24±48.51 min) was longer than group T (160.42±12.66 min). Duration of analgesia postoperatively (first rescue analgesic) was 619.96±26.96 min in group B, whereas it was 290.2±20.38 min in group T. Conclusion Butorphanol is more potent and produces longer duration of postoperative analgesia than tramadol, with an extra advantage of sedation and calmness.
背景随着阿片受体的出现,各种阿片药物被添加到用于外周阻滞的局部麻醉混合物中,以提高阻滞的质量和持续时间。在这项研究中,我们比较了布托啡诺和曲马多作为骨科上肢手术辅助剂的效果。患者和方法本研究选取50例年龄在18 ~ 60岁之间,美国麻醉师学会I级和II级,每组男女均可,均行上肢矫形手术经腋窝臂丛阻滞。局麻合剂中加入布托啡诺2 mg (B组)和曲马多100 mg (T组)。观察两组患者感觉和运动阻滞的发生情况、阻滞程度及并发症的发生情况。采用视觉模拟评分法观察患者术后镇痛情况。结果与T组(7.54±0.88和4.6±0.73)相比,B组感觉和运动阻滞的起效时间(min)分别延迟(8.76±1.0和5.86±0.71)。B组感觉阻滞持续时间(291.24±48.51 min)明显长于T组(160.42±12.66 min)。B组术后镇痛时间(首次抢救镇痛)为619.96±26.96 min, t组为290.2±20.38 min。结论布托啡诺比曲马多更有效,术后镇痛持续时间更长,具有镇静镇静的优势。
{"title":"Comparison of butorphanol and tramadol as an adjuvant to local anesthetic drug in axillary brachial plexus block","authors":"U. Bhatia, Gauri. M Panjabi, Atisha Patel","doi":"10.4103/asja.asja_51_16","DOIUrl":"https://doi.org/10.4103/asja.asja_51_16","url":null,"abstract":"Background With the advent of opioid receptors, a variety of opioid agents are added to local anesthetic mixtures used in peripheral blocks to improve the quality and duration of block. In this study, we compared the effect of butorphanol and tramadol as adjuvant agents for orthopedic upper extremity surgery. Patients and methods This study was carried out on 50 patients aged between 18 and 60 years, of American Society of Anesthesiologists grades I and II, of either sexes in each group, undergoing orthopedic upper limb surgeries through axillary brachial plexus block. An injection of butorphanol 2 mg (group B) and that of tramadol 100 mg (group T) were added to local anesthetic mixture. Onset of sensory and motor blockade, extent of blockade, and occurrence of any complications were studied in both groups. All patients were observed for analgesia postoperatively by visual analog scale pain score. Results In our study, the onset time (minutes) of sensory and motor blockade was delayed in group B (8.76±1.0 and 5.86±0.71, respectively) as compared with group T (7.54±0.88 and 4.6±0.73, respectively). In group B, the duration of sensory block (291.24±48.51 min) was longer than group T (160.42±12.66 min). Duration of analgesia postoperatively (first rescue analgesic) was 619.96±26.96 min in group B, whereas it was 290.2±20.38 min in group T. Conclusion Butorphanol is more potent and produces longer duration of postoperative analgesia than tramadol, with an extra advantage of sedation and calmness.","PeriodicalId":7492,"journal":{"name":"Ain-Shams Journal of Anaesthesiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77598621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
期刊
Ain-Shams Journal of Anaesthesiology
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