埃塞俄比亚南部哈迪亚区胡萨纳镇卫生设施中结核病不接受治疗的决定因素

B. B. Billoro, M. H. Nunemo
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引用次数: 1

摘要

背景:不坚持治疗导致结核病持续传播,产生耐药性,给患者和社区带来严重风险。目的:评估埃塞俄比亚南部胡萨纳镇卫生机构结核病患者结核病违约的决定因素。方法:2010年1月1日至2012年12月30日进行病例对照研究。采用双变量和多变量logistic回归分析,在p值< 0.05和95% CI下确定默认变量的最终预测因子。结果:共纳入调查对象128人。其中,对照组64例,病例64例。病人住在私人住宅,房子相对是4.12(优势比(95% ci) = 4.12(4) 1.1, 15日)和42.7(优势比(95% ci) = 42.7(8.5, 213)],倍违约相比病人分别住在自己的房子里,患者没有经验的耻辱被发现的几率减少违约(优势比(95% ci) = 0.1(0.03, 0.44)]和患者没有意识的结核病治疗期是22倍违约(优势比(95% ci) = 22.6(4.3, 118)]。结论:对结核病治疗期、住房状况和污名化经历的不了解与拖欠结核病药物有统计学意义。
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Determinants of Defaulting Tuberculosis Treatment in Hosanna town health facility, Hadiya Zone, South Ethiopia
Background: Treatment non-adherence leads to continuing tuberculosis (TB) transmission, development of drug resistance, resulting in serious risks for patient and for community. Objective: To assess determinant factors of TB defaulting among TB patients in Hosanna town health facility, South Ethiopia. Method: an unmatched case control study was conducted from January 1, 2010 to December 30, 2012. Bivariate and multivariate logistic regression analysis were performed to determine final predictors of defaulting variable at P-value < 0.05 and 95% CI. Result: A total of 128 respondents were included. Among those, 64 of them were controls and 64 were cases. Patients who live in private house and in relative house were 4.12 [AOR (95%CI) = 4.12 (1.1, 15, 4)] and 42.7 [AOR (95%CI) = 42.7(8.5, 213)], times more likely to default as compared to patients who live in their own house respectively ,patients who haven’t experience of stigma were found to decrease odds of defaulting [AOR (95%CI) = 0.1(0.03, 0.44)] and patients who have no awareness of TB treatment period were 22 times more likely to default [AOR (95%CI) = 22.6 (4.3, 118)]. Conclusion: Inadequate knowledge about TB treatment period, housing status, and experience of stigmatization were found to be statistically significant with defaulting TB drug.
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