{"title":"疟疾寄生虫感染与氯喹致瘙痒:阿片肽的作用","authors":"O. Adeyemi, E. Iwalewa, M. Akanmu, O. Ukponmwan","doi":"10.4314/WAJPDR.V22I1.14765","DOIUrl":null,"url":null,"abstract":"Pruritus or itch is associated with malaria infection and/or chloroquine chemotherapy. This study examined the relationship between parasitaemia and chloroquine (CQ) on body scratching (BS) in healthy (un-infected) and malaria-infected rats. The malaria parasite induced a significant (p Keywords : Rats, parasitaemia, chloroquine, opioids, antihistamine, naltrexone West African Journal of Pharmacology and Drug Research Vol. 22/23 2007: pp. 31-38","PeriodicalId":23624,"journal":{"name":"West African journal of pharmacology and drug research","volume":"32 1","pages":"31-38"},"PeriodicalIF":0.0000,"publicationDate":"2008-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Malaria Parasite Infection and Chloroquine-Induced Pruritus: The Role of Opioid-Peptides\",\"authors\":\"O. Adeyemi, E. Iwalewa, M. Akanmu, O. Ukponmwan\",\"doi\":\"10.4314/WAJPDR.V22I1.14765\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Pruritus or itch is associated with malaria infection and/or chloroquine chemotherapy. This study examined the relationship between parasitaemia and chloroquine (CQ) on body scratching (BS) in healthy (un-infected) and malaria-infected rats. The malaria parasite induced a significant (p Keywords : Rats, parasitaemia, chloroquine, opioids, antihistamine, naltrexone West African Journal of Pharmacology and Drug Research Vol. 22/23 2007: pp. 31-38\",\"PeriodicalId\":23624,\"journal\":{\"name\":\"West African journal of pharmacology and drug research\",\"volume\":\"32 1\",\"pages\":\"31-38\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2008-10-22\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"West African journal of pharmacology and drug research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4314/WAJPDR.V22I1.14765\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"West African journal of pharmacology and drug research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4314/WAJPDR.V22I1.14765","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
瘙痒或发痒与疟疾感染和/或氯喹化疗有关。本研究探讨了寄生虫血症与氯喹(CQ)对健康(未感染)和疟疾感染大鼠身体抓伤(BS)的影响。关键词:大鼠，寄生虫血症，氯喹，阿片类药物，抗组胺药，纳曲酮。西非药理学与药物研究Vol 22/23 2007: pp. 31-38
Malaria Parasite Infection and Chloroquine-Induced Pruritus: The Role of Opioid-Peptides
Pruritus or itch is associated with malaria infection and/or chloroquine chemotherapy. This study examined the relationship between parasitaemia and chloroquine (CQ) on body scratching (BS) in healthy (un-infected) and malaria-infected rats. The malaria parasite induced a significant (p Keywords : Rats, parasitaemia, chloroquine, opioids, antihistamine, naltrexone West African Journal of Pharmacology and Drug Research Vol. 22/23 2007: pp. 31-38
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