EarSpiro:用于肺功能评估的耳机肺活量测定法

Wentao Xie, Qing Hu, Jin Zhang, Qian Zhang
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摘要

肺活量测定法是评价肺功能的金标准。最近的研究表明,移动设备可以经济有效地测量肺功能指数。然而,这些设计在两个方面存在不足。首先,他们不能提供比肺功能指标更有信息量的流量-体积(F-V)曲线。其次,这些溶液缺乏吸气测量,对可变胸外梗阻等肺部疾病很敏感。在本文中,我们介绍了EarSpiro,一种基于耳机的解决方案,可以将肺活量测定测试中记录的气流声音解释为F-V曲线,包括呼气和吸气测量。EarSpiro利用卷积神经网络(CNN)和循环神经网络(RNN)来捕捉气流声音和气流速度之间的复杂相关性。同时,EarSpiro采用基于聚类的分割算法,对原始录音中的微弱吸气信号进行跟踪,实现吸气测量。我们还为EarSpiro提供了日常的类似于吹嘴的对象,例如使用迁移学习的漏斗和解码器网络,仅使用用户的一些真实肺功能指数。对60名受试者进行的大量实验表明,EarSpiro的平均误差为0。20𝐿/𝑠和0。42𝐿/𝑠用于呼气和吸气流速估算,0。61𝐿/𝑠和0。83𝐿/𝑠呼气和吸气F-V曲线估计。估计的F-V曲线与真实曲线的平均相关系数为0。94. 四种常用肺功能指标的平均估计误差为7。3%。
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EarSpiro: Earphone-based Spirometry for Lung Function Assessment
Spirometry is the gold standard for evaluating lung functions. Recent research has proposed that mobile devices can measure lung function indices cost-efficiently. However, these designs fall short in two aspects. First, they cannot provide the flow-volume (F-V) curve, which is more informative than lung function indices. Secondly, these solutions lack inspiratory measurement, which is sensitive to lung diseases such as variable extrathoracic obstruction. In this paper, we present EarSpiro, an earphone-based solution that interprets the recorded airflow sound during a spirometry test into an F-V curve, including both the expiratory and inspiratory measurements. EarSpiro leverages a convolutional neural network (CNN) and a recurrent neural network (RNN) to capture the complex correlation between airflow sound and airflow speed. Meanwhile, EarSpiro adopts a clustering-based segmentation algorithm to track the weak inspiratory signals from the raw audio recording to enable inspiratory measurement. We also enable EarSpiro with daily mouthpiece-like objects such as a funnel using transfer learning and a decoder network with the help of only a few true lung function indices from the user. Extensive experiments with 60 subjects show that EarSpiro achieves mean errors of 0 . 20 𝐿 / 𝑠 and 0 . 42 𝐿 / 𝑠 for expiratory and inspiratory flow rate estimation, and 0 . 61 𝐿 / 𝑠 and 0 . 83 𝐿 / 𝑠 for expiratory and inspiratory F-V curve estimation. The mean correlation coefficient between the estimated F-V curve and the true one is 0 . 94. The mean estimation error for four common lung function indices is 7 . 3%.
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