多频微波成像用于脑卒中检测

Q4 Biochemistry, Genetics and Molecular Biology Molecular & Cellular Biomechanics Pub Date : 2020-01-01 DOI:10.32604/mcb.2019.07101
Lulu Wang
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引用次数: 1

摘要

早期诊断并及时治疗可显著减少成人永久性残疾[0]。传统的医学成像工具,如x射线、超声、计算机断层扫描(CT)、磁共振成像(MRI)和正电子发射断层扫描(PET)等,已广泛用于脑部疾病的诊断。然而,每种方法都有一些局限性。x射线成像对人体产生有害辐射,由于健康组织和异常组织在x射线频率[2]下介电特性对比相对较小,因此对早期异常组织的识别具有挑战性。PET提供了有关软组织的有用信息,但价格昂贵且分辨率较差。CT和MRI由于产生有害辐射(CT)、昂贵(MRI)、耗时和不易开发便携式系统而不适合连续监测脑卒中[3,4]。因此,迫切需要开发一种新的筛查方法来提高疾病检测的有效性。微波成像是一种相对较新的、无创的、低成本的乳腺和脑组织成像方法,在过去的两年中不断引起许多研究者的兴趣。作者先前开发了一种用于介质目标检测的全息微波成像(HMI)方法,特别是针对脑卒中,本文探讨了多频HMI用于脑卒中检测的可行性。开发了一个数值系统来证明所提出的理论。进行了各种实验来评估所提出方法的性能。用多频人机界面与单频人机界面的实验结果进行了比较。结果表明,与单频HMI算法相比,多频HMI算法可以检测笔画,并提供更准确的笔画大小和位置结果。
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Multifrequency Microwave Imaging for Brain Stroke Detection
: Early diagnosis of stroke with timely treatment could reduce adult permanent disability significantly [1]. Conventional medical imaging tools such as X-ray, ultrasound, computed tomography (CT), magnetic resonance imaging (MRI) and positron emission tomography (PET) have been widely used for diagnosis of brain disease. However, each of these methods has some limitations. X-ray imaging produces harmful radiation to the human body and challenging to identify early-stage abnormal tissue due to the relatively small dielectric proprieties contrast between the healthy tissue and abnormal tissue at X-ray frequencies [2]. PET provides useful information about soft tissues, but it is expensive and produces poor resolution. CT and MRI are unsuitable for continuously monitoring strokes due to produce harmful radiations (CT), expensive (MRI), time-consuming and not easy to develop a portable system [3,4]. Therefore, develop a new screening method is urgently needed to improve the effectiveness of disease detection. Microwave imaging is a relatively new non-invasive and cost-effective method for imaging of breast and brain tissues, which has continuously attracted many researchers’ interests the past two The authors previously developed a holographic microwave imaging (HMI) method for dielectric object detection with a particular focus on brain stroke This paper investigates the feasibility of multifrequency HMI for brain stroke detection. A numerical system was developed to demonstrate the proposed theory. Various experiments were carried out to evaluate the performance of the proposed method. Results of experiments carried out using multifrequency HMI have been compared with the results obtained by using single frequency HMI. Results showed that multifrequency HMI could detect strokes and provide more accurate results of size and location than the single frequency HMI algorithm.
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来源期刊
Molecular & Cellular Biomechanics
Molecular & Cellular Biomechanics CELL BIOLOGYENGINEERING, BIOMEDICAL&-ENGINEERING, BIOMEDICAL
CiteScore
1.70
自引率
0.00%
发文量
21
期刊介绍: The field of biomechanics concerns with motion, deformation, and forces in biological systems. With the explosive progress in molecular biology, genomic engineering, bioimaging, and nanotechnology, there will be an ever-increasing generation of knowledge and information concerning the mechanobiology of genes, proteins, cells, tissues, and organs. Such information will bring new diagnostic tools, new therapeutic approaches, and new knowledge on ourselves and our interactions with our environment. It becomes apparent that biomechanics focusing on molecules, cells as well as tissues and organs is an important aspect of modern biomedical sciences. The aims of this journal are to facilitate the studies of the mechanics of biomolecules (including proteins, genes, cytoskeletons, etc.), cells (and their interactions with extracellular matrix), tissues and organs, the development of relevant advanced mathematical methods, and the discovery of biological secrets. As science concerns only with relative truth, we seek ideas that are state-of-the-art, which may be controversial, but stimulate and promote new ideas, new techniques, and new applications.
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