“达摩”国立肿瘤医院盆腔癌临床研究综述

E. Suzanna, A. Adisasmita, Pradnya Sri Rahayu, G. Shalmont
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摘要

背景:盆腔是由盆腔脏器的骨骼组成,其中有许多系统器官。2005 - 2007年雅加达的盆腔癌发病率为13.96/10万人。在“Dharmais”国家癌症医院(DNCH), 1993-2007年的发病率占所有癌症的26%。研究的目的是了解流行病学(年龄组、性别、住所、教育程度、婚姻状况、肿瘤位置)和临床(症状和分期)盆腔癌的概况。方法:本横断面研究采用2005-2007年登记为DNCH新病例并经显微镜检查诊断的患者病历。本研究人群为一例癌症,诊断原发肿瘤位置在盆腔区域。样本计算采用精度公式,得到最小样本为323。数据收集采用问卷调查法,共获得326例。数据采用SPSS 26.0进行统计学分析,χ 2检验(α = 0.05)。结果:盆腔癌以女性为主(91.1%),以45-59岁为高峰。男性和女性的临床特征差异分别为24和35。在男性中,最常见的临床特征是深色/血便(41.38%),一般在直肠癌中,其次是体重减轻(20.69%),在五个器官重叠。在女性中,最常见的临床特征是阴道出血(43.77%)和阴道斑点(13.47%),发生在宫颈癌中,其次是腹部疼痛(13.47%),在六个器官重叠。结论:癌症,尤其是原发性盆腔肿瘤,并不是一种“沉默的杀手”疾病,因为临床表现可以在早期出现。本研究也为盆腔原发性肿瘤患者提供了一个共同的临床图像,即使它们在一个腔内。临床表现根据原发肿瘤的不同而不同。此外,有些症状是由多个器官共同具有的,因此是非特异性的。
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Various Clinical Overviews in Pelvic Cavity Cancer In “Dharmais” National Cancer Hospital (DNCH)
Background: Pelvic cavity is formed by the bones of pelvic organs where there are many system organs. Pelvic cavity cancer incidence in Jakarta from 2005 to 2007 was 13.96/100.000 population. In “Dharmais” National Cancer Hospital (DNCH), the frequency in 1993-2007 was 26% of all cancer. The purpose of the research is to find an overview of epidemiological (age group, gender, domicile, educational, marital status, tumor location) and clinical (symptoms and stage) cancer pelvic cavity. Methods: This cross-sectional study used the medical records of patients registered with DNCH as new cases and diagnosed by microscopic examination during 2005-2007. The study population is a case of cancer with the diagnosis of the location of the primary tumor in the pelvic cavity area. The sample calculation used a precision formula and obtained a minimum sample of 323. The data collection used questionnaires and obtained 326 cases. The data were analyzed using SPSS 26.0 with Chi-square test (α = 0.05).Results: Pelvic cavity cancer is a major problem in females (91.1%) with peak ages 45-59. Variations of clinical features in males and females were 24 and 35 symptomatic. In males, the most common clinical feature is dark/blood stool (41.38%), generally on rectal cancer, followed by weight loss (20.69%) which overlaps at five organs. In females, the most common clinical features are vaginal bleeding (43.77%), and vaginal spotting (13.47%), which occurs in cervix cancer, followed by abdominal pain (13.47%) that overlaps in six organs. Conclusions: Cancer, especially primary tumors of the pelvic cavity, is not a “silent killer” disease because the clinical picture can appear at an early stage. This study also provides a common clinical picture in patients with primary tumors in the pelvic cavity even though they are in one cavity. The clinical picture that appears is specific according to the primary tumor. In addition, some symptoms are possessed by various organs, so they are nonspecific.
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