在癫痫患者中冒充补充和替代医学(CAM)的庸医

Sangeeta Sharma, S. Joshi, S. Khushwaha, K. Bala
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引用次数: 2

摘要

患有癫痫等慢性疾病的患者经常使用补充和替代医学(CAM)作为一线治疗,因为这种疾病带有神话、迷信和耻辱。本研究报告了108例癫痫患者在对抗疗法医院出现不受控制的癫痫发作,癫痫持续状态或药物毒性。这些患者的血液样本从专门治疗癫痫的CAM供应商那里服用未标记的药片,其中含有处方抗癫痫药物(aed),如卡马西平、苯妥英、丙戊酸和苯巴比妥。除5例患者外,所有患者的血清样本均显示存在一种或多种aed。大多数患者的血清抗癫痫药水平在亚治疗或超治疗范围内。作者提醒临床医生,求助于“安全”或“天然”CAM的患者最终可能会从未经授权的CAM提供者那里获得有毒或亚治疗剂量的现代处方药。
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Quackery Masquerading as Complementary and Alternative Medicine (CAM) in Patients With Epilepsy
Patients suffering from chronic diseases like epilepsy often use complementary and alternative medicine (CAM) as first-line treatment because of myths, superstitions, and stigma attached to the disease. The present study reports on 108 patients with epilepsy presenting to an allopathic hospital with uncontrolled seizures, status epilepticus, or drug toxicity. Blood samples of these patients taking unlabeled pills from a CAM provider specializing in the treatment of epilepsy contained prescription antiepileptic drugs (AEDs) such as carbamazepine, phenytoin, valproic acid, and phenobarbitone. Serum samples in all but 5 patients demonstrated presence of one or more AEDs. Most of the patients had serum levels of these AEDs either in the subtherapeutic or in the supratherapeutic range. The authors alert clinicians that the patients resorting to “safe” or “natural” CAM may end up receiving modern prescription medicines from unauthorized CAM providers in toxic or subtherapeutic doses.
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