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Vitamin B2: Riboflavin 维生素B2:核黄素
Pub Date : 2011-04-01 DOI: 10.1177/1533210110392943
Bruce A Buehler
Riboflavin (vitamin B 2) is not synthesized by vertebrates and must be supplied by diet. It is found in most foods, with the highest content in dairy products, meat, and dark green vegetables. Deficiency rarely occurs alone where adequate food is available and usually occurs as a multinutrient deficiency. Some conditions and medications can decrease effectiveness or levels of riboflavin. Supplementation is rarely needed to prevent ariboflavinosis when a normal diet is consumed. Supplementation for decreased frequency of migraine headaches and prevention of age related cataracts could be beneficial. There is no known toxicity.
核黄素(维生素b2)不能由脊椎动物合成,必须通过饮食提供。它存在于大多数食物中,乳制品、肉类和深绿色蔬菜中含量最高。在食物充足的情况下,缺乏很少单独发生,通常是多种营养素缺乏症。某些情况和药物会降低核黄素的有效性或水平。当正常饮食时,很少需要补充来预防黄酮症。补充减少偏头痛的频率和预防年龄相关性白内障可能是有益的。没有已知的毒性。
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引用次数: 3
Clinical Meditation Teacher: A New Role for Health Professionals 临床冥想教师:卫生专业人员的新角色
Pub Date : 2011-04-01 DOI: 10.1177/2156587211399578
R. Schaub
The support for integrating meditation into health care and mental health has reached scientific and public acceptance. For the public to receive the benefits of the mind—body medicine of meditation, it is time for health professionals to step into the role of clinical meditation teachers. Clinical meditation refers to the ability to discern the right kinds of meditation for the right person at the right time. With the increased emphasis on preventative medicine and self-care skills to reduce health care costs, the timing is absolutely appropriate for health professionals to gain skills in this new role.
将冥想纳入医疗保健和心理健康的支持已得到科学界和公众的认可。为了让公众获得冥想的身心医学的好处,现在是卫生专业人员进入临床冥想教师角色的时候了。临床冥想是指在正确的时间为正确的人辨别正确的冥想方式的能力。随着对预防医学和自我保健技能的日益重视,以降低卫生保健成本,卫生专业人员在这个新角色中获得技能的时机是绝对合适的。
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引用次数: 6
Folic Acid: Beyond Metabolism 叶酸:超越新陈代谢
Pub Date : 2011-03-24 DOI: 10.1177/1533210110392950
M. Lucock
Mandatory and discretionary fortification with folic acid is eliminating deficiency of this vitamin. Blood levels of the vitamin have never been higher, with hematologic folate values commonly exceeding the upper range of calibration. The synthetic analog (pteroylmonoglutamic acid) prevents neural tube defects and lowers homocysteine, both positive attributes, yet negative correlates of pteroylmonoglutamic acid are increasingly reported. These involve increased risk for common cancers (ie, colon, breast, prostate) and antimetabolite effects on natural killer cells and at dihydrofolate reductase, a critical gatekeeper enzyme. This review, however, takes a different, human ecological perspective, examining novel folate-related phenomena distinct from the classic metabolic role of the vitamin in maintaining health and well-being. An argument is developed that at molecular, cellular, and organism levels, folate is crucial to some important events that link light to life.
强制和随意的叶酸强化可以消除这种维生素的缺乏。血液中维生素的含量从未如此之高,血液叶酸值通常超过校准的上限。合成的类似物(翼酰基单胺酸)可以防止神经管缺陷并降低同型半胱氨酸,这两个都是积极的属性,但越来越多的报道显示翼酰基单胺酸具有负相关。这包括增加患常见癌症(如结肠癌、乳腺癌、前列腺癌)的风险,以及对自然杀伤细胞和关键的门卫酶二氢叶酸还原酶的抗代谢作用。然而,这篇综述采取了不同的人类生态学观点,研究了不同于维生素在维持健康和福祉中的经典代谢作用的与叶酸相关的新现象。有一种观点认为,在分子、细胞和有机体的水平上,叶酸对于将光与生命联系起来的一些重要事件是至关重要的。
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引用次数: 19
Christina M. Puchalski and Betty Ferrell Making Health Care Whole: Integrating Spirituality Into Health Care West Conshohocken, PA: Templeton Press, 2010. 266 pp. $34.95. ISBN 978-1-59947-350-5 Christina M. Puchalski和Betty Ferrell使医疗保健整体:将灵性融入医疗保健West Conshohocken, PA: Templeton Press, 2010。266页,34.95美元。ISBN 978-1-59947-350-5
Pub Date : 2011-03-24 DOI: 10.1177/2156587211401623
R. Brumback
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引用次数: 1
Patricia Callone and Connie Kudlacek The Alzheimer’s Caregiving Puzzle: Putting Together the Pieces New York, NY: Demos Medical Publishing, 2010. 216 pp. $16.95. ISBN 978-1-932603880 帕特里夏·卡龙和康妮·库德拉切克:《老年痴呆症护理难题:拼凑碎片》纽约,纽约:Demos医学出版社,2010年。216页,16.95美元。ISBN 978-1-932603880
Pub Date : 2011-03-24 DOI: 10.1177/2156587211399440
K. K. York
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引用次数: 1
Mythology of Antioxidant Vitamins? 抗氧化维生素的神话?
Pub Date : 2011-03-24 DOI: 10.1177/1533210110392955
R. M. Howes
Decades of overly exuberant antioxidant vitamin claims, regarding disease prevention and antiaging, have not been supported by rigorous scientific testing and negative studies have been largely denied or ignored by the dietary supplement industry. Myths, half truths, and outright lies are commonly used to promote their sales since there is minimal governmental oversight of their effectiveness or of their harmful potential. The free radical theory, which served as the basis of antioxidant vitamin studies to prevent disease, lacks predictability, fails to meet the requirements of the scientific method, and has consequently been invalidated. Antioxidant vitamins have such widespread use that their potential to do harm has become a global public health issue. We must follow the fundamental medical precept of Hippocrates: ‘‘First, do no harm.’’ We must separate fact from factitious and ‘‘myths of marketing’’ from scientific truths.
几十年来,关于疾病预防和抗衰老的过度活跃的抗氧化维生素声称,没有得到严格的科学测试的支持,负面研究在很大程度上被膳食补充剂行业否认或忽视。神话、半真半假和彻头彻尾的谎言通常被用来促进它们的销售,因为政府对它们的有效性或潜在危害的监督微乎其微。作为抗氧化维生素预防疾病研究基础的自由基理论缺乏可预见性,不符合科学方法的要求,因此被宣告无效。抗氧化维生素被广泛使用,其潜在危害已成为一个全球性的公共卫生问题。我们必须遵循希波克拉底的基本医疗准则:“首先,不要伤害他人。我们必须将事实与人为的、“营销神话”与科学真理区分开来。
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引用次数: 5
Does Vitamin E and C Supplementation Improve the Recovery From Anterior Cruciate Ligament Surgery? 补充维生素E和C能提高前交叉韧带手术后的恢复吗?
Pub Date : 2011-03-24 DOI: 10.1177/1533210110392954
T. Barker, M. Traber
Muscular (quadriceps) weakness is a predominant impairment that follows anterior cruciate ligament injury and surgery. This continued weakness impairs activities of daily living and could predispose patients to adverse conditions later in life, such as knee osteoarthritis. Vitamins E and C have potent antioxidant and anti-inflammatory activity. Herein, the authors summarize the state-of-the science and suggest directions for future research endeavors regarding the therapeutic influence of vitamins E and C, or other antioxidants, on the recovery from anterior cruciate ligament injury and surgery.
肌肉(股四头肌)无力是前交叉韧带损伤和手术后的主要损伤。这种持续的虚弱损害了日常生活的活动,并可能使患者在以后的生活中易患不良疾病,如膝关节骨关节炎。维生素E和C具有强大的抗氧化和抗炎活性。在此,作者总结了目前的科学现状,并就维生素E和C或其他抗氧化剂对前交叉韧带损伤和手术后恢复的治疗作用提出了未来研究的方向。
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引用次数: 2
Pharmacologic Use of Niacin 烟酸的药理学用途
Pub Date : 2011-02-27 DOI: 10.1177/2156587211399579
Jonathan E. Prousky, C. Millman, J. Kirkland
Niacin is required for a host of critical redox and adenosine diphosphate-ribosylation reactions in metabolism. Niacin deficiency leads to the distinctive signs and symptoms of pellagra, but these can happen in an unpredictable progression and can be altered in patients with polymorphisms in any of the hundreds of niacin-dependent enzymes. The symptomatology of niacin deficiency is becoming a forgotten knowledge base, and niacin deficiency is likely underdiagnosed. Additionally, high levels of niacin and niacinamide have pharmacological effects distinct from their role as sources of vitamin B3, allowing a wide range of effects on processes such as blood flow and lipid metabolism, which can be used to treat or prevent a variety of disease processes.
烟酸是代谢中一系列关键的氧化还原和二磷酸腺苷-核糖基化反应所必需的。烟酸缺乏导致糙皮病的独特体征和症状,但这些可能以不可预测的进展发生,并且可能在数百种烟酸依赖酶的任何一种多态性的患者中发生改变。烟酸缺乏症的症状学正在成为一个被遗忘的知识基础,烟酸缺乏症很可能被误诊。此外,高水平的烟酸和烟酰胺具有不同于它们作为维生素B3来源的药理作用,允许对血流和脂质代谢等过程产生广泛影响,可用于治疗或预防各种疾病过程。
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引用次数: 17
Coenzyme Q10: Clinical Update and Bioavailability 辅酶Q10:临床更新和生物利用度
Pub Date : 2011-02-27 DOI: 10.1177/2156587211399438
Ginny Bank, Daniel I. Kagan, D. Madhavi
Coenzyme Q10 (CoQ 10) supplementation has been reported to be beneficial in treating a variety of health conditions and diseases, with more than 200 clinical trials investigating its use as a drug or dietary supplement. Numerous reviews of the safety and clinical potential of CoQ10 have been published. Successful treatment and efficacy is dependent on the bioavailability of CoQ 10, which is well known to be poor because of its lipophilic nature and large molecular weight. A number of recent clinical trials on CoQ 10 have investigated new formulations of CoQ10 for improvements in absorption and bioavailability. This review provides an update of clinical efficacy trials using CoQ10 and describes recent advances in formulation technology to improve the bioavailability of CoQ10. The authors also discuss a new method to improve the standards of reporting the bioavailability results of such advanced CoQ10 formulations to help clinicians and consumers make informed decisions.
据报道,辅酶Q10 (coq10)补充剂对治疗多种健康状况和疾病有益,已有200多项临床试验调查其作为药物或膳食补充剂的用途。许多关于辅酶q10的安全性和临床潜力的评论已经发表。成功的治疗和疗效取决于coq10的生物利用度,众所周知,由于其亲脂性和大分子量,coq10的生物利用度很差。最近一些关于辅酶q10的临床试验研究了辅酶q10的新配方,以改善吸收和生物利用度。本文综述了使用辅酶q10的临床疗效试验的最新进展,并描述了提高辅酶q10生物利用度的配方技术的最新进展。作者还讨论了一种新的方法来提高报告这种先进的辅酶q10配方的生物利用度结果的标准,以帮助临床医生和消费者做出明智的决定。
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引用次数: 37
Calcium: An Essential Mineral 钙:一种必需的矿物质
Pub Date : 2011-02-27 DOI: 10.1177/2156587211399439
Elaine D. Mackowiak
This review of calcium discusses briefly the role of the parathyroid glands, the gastrointestinal system, and the renal system in maintaining calcium homeostasis that is required for normal bone health, nerve and muscle function, and blood coagulation in the human body. The new recommendations for calcium intake by the United States Institute of Medicine are discussed. The concerns by the Institute of Medicine regarding adverse effects from excess calcium intake, especially hypercalcemia, nephrolithiasis (kidney stones), milk alkali syndrome, prostate cancer, and coronary heart disease, are reviewed.
这篇关于钙的综述简要讨论了甲状旁腺、胃肠道系统和肾脏系统在维持人体正常骨骼健康、神经和肌肉功能以及血液凝固所需要的钙稳态中的作用。讨论了美国医学研究所关于钙摄入量的新建议。医学研究所对过量钙摄入的不良影响,特别是高钙血症、肾结石、乳碱综合征、前列腺癌和冠心病的关注进行了综述。
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引用次数: 1
期刊
Complementary Health Practice Review
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