J. Marazzato, G. Cappabianca, F. Angeli, Matteo Crippa, M. Golino, S. Ferrarese, C. Beghi, R. De Ponti
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The electrophysiologic mechanism (focal vs. reentrant arrhythmias), site of arrhythmia origin (left atrium vs. right atrium) and their anatomic correlation with specific surgical access and/or prior Cox-Maze IV procedure were all addressed.\n\n\nRESULTS\nEleven studies including 206 patients undergoing catheter ablation of 297 post-surgical arrhythmia morphologies occurring after mitral valve surgery were considered. Major complications were observed in 2 patients only (0.9%). Restoration of sinus rhythm was achieved in 96% of patients. Macro-reentrant arrhythmia was mostly observed (90.4%) with a non-negligible proportion of focal arrhythmia (9.6%). Left-sided arrhythmia was common (54.4%,) but cavotricuspid isthmus-dependent arrhythmia was frequently reported (33%). Although specific atriotomies showed trends towards peculiar locations of the investigated arrhythmia, Cox-Maze IV procedure was the only independent predictor for left-sided arrhythmia (OR=17.3; 95% CI 7.2-41.2; p<0.0001).\n\n\nCONCLUSIONS\nCatheter ablation of post-surgical arrhythmia occurring after mitral valve surgery is feasible, and, in this setting, the vast majority of the arrhythmia morphologies are based on macroreentry and in about one third of cases show cavotricuspid isthmus-dependent arrhythmia. 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引用次数: 4
摘要
背景:关于二尖瓣手术后心房心动过速的导管消融的资料很少。通过查阅文献,本研究旨在评估导管消融的可行性及消融心房心律失常患者的特点。方法选择评估心房心动过速主要手术参数和电生理表现的研究。电生理机制(局灶性与再入性心律失常)、心律失常起源部位(左心房与右心房)及其与特定手术通路和/或先前Cox-Maze IV手术的解剖相关性都得到了解决。结果对206例经导管消融的二尖瓣术后发生的297例心律失常形态进行了分析。仅2例(0.9%)出现严重并发症。96%的患者恢复了窦性心律。以大可重入性心律失常居多(90.4%),局灶性心律失常比例不可忽略(9.6%)。左侧心律失常很常见(54.4%),但三尖瓣峡部依赖性心律失常也经常被报道(33%)。尽管特定的心房切开术显示出所研究的心律失常的特殊位置的趋势,Cox-Maze IV手术是左侧心律失常的唯一独立预测因子(OR=17.3;95% ci 7.2-41.2;p < 0.0001)。结论导管消融治疗二尖瓣手术后发生的心律失常是可行的,在这种情况下,绝大多数心律失常形态学基于大再入,约三分之一的病例表现为腔三尖瓣峡部依赖性心律失常。先前的Cox-Maze-IV与二尖瓣手术相关是可能由非跨壁手术病变引起的左侧心律失常的独立预测因子。
Ablation of atrial tachycardia in the setting of prior mitral valve surgery.
BACKGROUND
Data regarding catheter ablation of post-surgical atrial tachycardia occurring after mitral valve surgery are scarce. Through a search of the literature, this study aimed to assess the feasibility of catheter ablation and the characteristics of atrial arrhythmias ablated in these patients.
METHODS
Studies assessing the main procedure parameters and the electrophysiologic findings of the investigated atrial tachycardia were selected. The electrophysiologic mechanism (focal vs. reentrant arrhythmias), site of arrhythmia origin (left atrium vs. right atrium) and their anatomic correlation with specific surgical access and/or prior Cox-Maze IV procedure were all addressed.
RESULTS
Eleven studies including 206 patients undergoing catheter ablation of 297 post-surgical arrhythmia morphologies occurring after mitral valve surgery were considered. Major complications were observed in 2 patients only (0.9%). Restoration of sinus rhythm was achieved in 96% of patients. Macro-reentrant arrhythmia was mostly observed (90.4%) with a non-negligible proportion of focal arrhythmia (9.6%). Left-sided arrhythmia was common (54.4%,) but cavotricuspid isthmus-dependent arrhythmia was frequently reported (33%). Although specific atriotomies showed trends towards peculiar locations of the investigated arrhythmia, Cox-Maze IV procedure was the only independent predictor for left-sided arrhythmia (OR=17.3; 95% CI 7.2-41.2; p<0.0001).
CONCLUSIONS
Catheter ablation of post-surgical arrhythmia occurring after mitral valve surgery is feasible, and, in this setting, the vast majority of the arrhythmia morphologies are based on macroreentry and in about one third of cases show cavotricuspid isthmus-dependent arrhythmia. Prior Cox-Maze-IV associated with mitral valve surgery is an independent predictor of left-sided arrhythmia possibly due to non-transmural surgical lesions.