2021-2022年流行季。呼吸道病毒病原体共同感染的频率

E. Burtseva, A. D. Panova, L. Kolobukhina, A. V. Ignatjeva, E. Kirillova, N. V. Breslav, S. Trushakova, E. Mukasheva, E. L. Feodoritova, K. Krasnoslobodtsev, L. N. Merkulova, I. N. Khlopova, L. Kisteneva, I. Kruzhkova, Yu. S. Levochkina, Anastasia S. Krepkaia, Aleksandra G. Rosatkevich, A. Komissarov, Svetlana B. Yatsishina, Andrey A. Pochtovyi, D. D. Kustova, V. V. Gushchin, M. Bazarova, S. Smetanina, N. Tsvetkova
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摘要

介绍。本工作的主要目的是在SARS-CoV-2和流感背景下,确定2021-2022年流行季节各种病毒性呼吸道病原体的传播特征,以及合并感染的频率。材料和方法。本文采用“传统”和“医院”两种流行病学监测方法对急性呼吸道病毒感染进行监测。结果和讨论。2021-2022年流行季的特点是甲型流感(H3N2)病毒的早期活动,以及新变种SARS-CoV-2(组粒)的出现和迅速传播。在2021-2022年流行季节,不同呼吸道病原体对感染份额的依赖性明显:SARS-CoV-2占主导地位(18.8%),其次是流感病毒(10.6%),最后是其他急性呼吸道病毒感染病原体(0.4%-3.7%)。关于甲型流感(H3N2)和乙型流感病毒,注意到其种群的异质性和与疫苗株相关的漂移变异性。各种呼吸道病原体合并感染的频率较低:根据“传统监测”-不超过0.1%,“医院监测”不超过9.2%。提出了更新2022-2023年北半球国家流感疫苗组成的理由。
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EPIDEMIC SEASON 2021-2022. FREQUENCY OF CO-INFECTION BY RESPIRATORY VIRAL PATHOGENS
Introduction. The main purpose of this work was to determine the characteristics of the circulation of various viral respiratory pathogens during the epidemic season 2021-2022, as well as the frequency of co-infection against the background of SARS-CoV-2 and influenza. Materials and methods. The article uses methods of "traditional" and "hospital" epidemiological surveillance for acute respiratory viral infections. Results and discussion. The epidemic season of 2021-2022 was characterized by the early activity of the influenza A(H3N2) virus, as well as the appearance and rapid spread of a new variant of SARS-CoV-2 (omicron). The dependence on the share of different respiratory pathogens during the epidemic season 2021-2022 was clearly traced: the dominant role belonged to SARS-CoV-2 (18.8%), then to influenza viruses (10.6%) and, finally, to pathogens of other acute respiratory viral infections (0.4%-3.7%). With respect to influenza A(H3N2) and B viruses, heterogeneity of their populations and drift-variability in relation to vaccine strains were noted. The frequency of co-infection with various respiratory pathogens was low: according to "traditional surveillance" - no more than 0.1%, "hospital surveillance" no more than 9.2%. The rationale for updating the composition of influenza vaccines for the countries of the Northern Hemisphere for 2022-2023 season was given.
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