{"title":"SNP阵列评价作为乌拉圭Corriedale羊遗传改良的工具","authors":"B. Carracelas, E. Navajas, B. Vera, G. Ciappesoni","doi":"10.31285/agro.26.998","DOIUrl":null,"url":null,"abstract":"One control strategy for gastrointestinal nematodes (GIN) is genetic selection. This study´s objective was to compare eggs per gram of feces (FEC) and fiber diameter (FD) estimated breeding values (EBV) and genomic EBV (GEBV) in Corriedale breed. Analysis included 19547 lambs with data, and 454, 711 and 383 genotypes from 170, 507 and 50K SNP chips, respectively. A univariate animal model was used for EBV and GEBV estimation, which included contemporary group, type of birth and dam age as fixed effects, and age at recording as covariate. Differential weights (α) were considered in the genomic relationship matrix (G), and the best fit models were identified using Akaike´s Information Criterion (AIC), which were later used for GEBV and accuracies estimation. The use of α only impacted on low density SNP chips. No differences were observed in mean accuracies for the whole population. However, in the genotyped subgroup accuracies increased by 2% with the 170 SNP chip (α=0.25), and by 5% (α=0.5) and 14% (α=0.75) with the 507 SNP chip. No differences were observed in FD EBV and GEBV mean accuracies. These results show that it is possible to increase GEBV accuracies despite the use of low-density chips.","PeriodicalId":43474,"journal":{"name":"Agrociencia-Uruguay","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"SNP arrays evaluation as tools in genetic improvement in Corriedale sheep in Uruguay\",\"authors\":\"B. Carracelas, E. Navajas, B. Vera, G. Ciappesoni\",\"doi\":\"10.31285/agro.26.998\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"One control strategy for gastrointestinal nematodes (GIN) is genetic selection. This study´s objective was to compare eggs per gram of feces (FEC) and fiber diameter (FD) estimated breeding values (EBV) and genomic EBV (GEBV) in Corriedale breed. Analysis included 19547 lambs with data, and 454, 711 and 383 genotypes from 170, 507 and 50K SNP chips, respectively. A univariate animal model was used for EBV and GEBV estimation, which included contemporary group, type of birth and dam age as fixed effects, and age at recording as covariate. Differential weights (α) were considered in the genomic relationship matrix (G), and the best fit models were identified using Akaike´s Information Criterion (AIC), which were later used for GEBV and accuracies estimation. The use of α only impacted on low density SNP chips. No differences were observed in mean accuracies for the whole population. However, in the genotyped subgroup accuracies increased by 2% with the 170 SNP chip (α=0.25), and by 5% (α=0.5) and 14% (α=0.75) with the 507 SNP chip. No differences were observed in FD EBV and GEBV mean accuracies. These results show that it is possible to increase GEBV accuracies despite the use of low-density chips.\",\"PeriodicalId\":43474,\"journal\":{\"name\":\"Agrociencia-Uruguay\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Agrociencia-Uruguay\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.31285/agro.26.998\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Agrociencia-Uruguay","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.31285/agro.26.998","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
SNP arrays evaluation as tools in genetic improvement in Corriedale sheep in Uruguay
One control strategy for gastrointestinal nematodes (GIN) is genetic selection. This study´s objective was to compare eggs per gram of feces (FEC) and fiber diameter (FD) estimated breeding values (EBV) and genomic EBV (GEBV) in Corriedale breed. Analysis included 19547 lambs with data, and 454, 711 and 383 genotypes from 170, 507 and 50K SNP chips, respectively. A univariate animal model was used for EBV and GEBV estimation, which included contemporary group, type of birth and dam age as fixed effects, and age at recording as covariate. Differential weights (α) were considered in the genomic relationship matrix (G), and the best fit models were identified using Akaike´s Information Criterion (AIC), which were later used for GEBV and accuracies estimation. The use of α only impacted on low density SNP chips. No differences were observed in mean accuracies for the whole population. However, in the genotyped subgroup accuracies increased by 2% with the 170 SNP chip (α=0.25), and by 5% (α=0.5) and 14% (α=0.75) with the 507 SNP chip. No differences were observed in FD EBV and GEBV mean accuracies. These results show that it is possible to increase GEBV accuracies despite the use of low-density chips.