常规与无缝线技术修复心上肺静脉全异位连接

Furong Liu, J. Zhuang, Jimei Chen, S. Wen, Gang Xu, J. Cen
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引用次数: 0

摘要

目的总结常规与无缝线技术治疗心上肺静脉全异位的经验。方法2004年1月至2016年1月,对150例心旁全异常肺静脉连接患者行常规或不缝合术。Kaplan-Meier曲线用于证明生存估计。采用Cox比例风险模型确定死亡和术后肺静脉阻塞(PVO)的危险因素。结果住院死亡9例,晚期死亡2例。30天、1年、12年生存率分别为94.0%、93.3%、92.7%。95.7%的幸存者完成了随访。中位随访时间为47个月(范围:0-136个月)。21例患者因肺静脉阻塞需再次手术。新生儿组生存率明显低于婴幼儿组(P=0.026)。对于术前诊断为PVO的患者,常规组和不缝合组的生存率(92.3% VS 93.9%, P=0.741)和再手术自由发生率(55.6% VS 90.9%, P=0.166)相似。多因素分析显示,术前肺静脉阻塞(P=0.015)和通气时间延长(P=0.011)是增加的死亡危险因素。主动脉交叉夹持时间与术后肺静脉阻塞相关(P=0.038)。结论常规和无缝线技术均可获得满意的效果。关键词:全异常肺静脉连接;手术结果;肺静脉阻塞;Sutureless技术
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Conventional and sutureless techniques for surgical repair of supracardiac total anomalous pulmonary venous connection
Objective To review our experiences with conventional and sutureless techniques in patients with supracardiac total anomalous pulmonary venous connection. Methods From January 2004 to January 2016, 150 patients with suparacardiac total anomalous pulmonary venous connection underwent conventional or sutureless techniques. Kaplan-Meier curve was used to demonstrate the survival estimates. Cox proportional hazard model was used to identify risk factors for death and postoperative pulmonary venous obstruction(PVO). Results There were 9 in-hospital deaths and 2 late deaths. The survival rates at 30 days, 1 year, and 12 years were 94.0%, 93.3%, and 92.7%, respectively. Follow-up was completed in 95.7% of the survivors. Median follow-up was 47 months(range: 0-136 months). Twenty-one patients required reoperation for pulmonary venous obstruction. The survival rates in neonate group is significantly lower than that in infants and children group(P=0.026). For those who were diagnosed with preoperative PVO, the survival rates(conventional group 92.3% VS sutureless group 93.9%, P=0.741) and incidence of freedom from reoperation(conventional group 55.6% VS sutureless group 90.9%, P=0.166) in both the conventional and sutureless group were similar. Multivariable analysis showed that preoperative pulmonary venous obstruction(P=0.015) and longer duration of ventilation(P=0.011) were incremental risk factors for death. Aortic cross-clamp time(P=0.038) was associated with postoperative pulmonary venous obstruction. Conclusion Both the conventional and sutureless techniques in surgical repair for supracardiac total anomalous pulmonary venous connection can achieve satisfactory outcomes. Key words: Total anomalous pulmonary venous connection; Surgical outcomes; Pulmonary venous obstruction; Sutureless technique
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