尼日利亚西南部伊巴丹市小学生食物过敏和寄生虫感染流行情况

A. Adelakun, O. Arinola
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引用次数: 2

摘要

背景:食物过敏是西方世界的一个问题,然而,在发展中国家也发现了食物过敏的病例。在尼日利亚,食物过敏的患病率很低,而食物致敏与蠕虫病的关系尚不清楚。目的:本研究旨在确定尼日利亚学龄儿童对食物过敏的患病率及其与肠道蠕虫病的关系。方法:从尼日利亚伊巴丹Sango的CAC小学招募了128名参与者。采用新鲜制备的食物过敏原进行皮肤点刺试验。采集粪便标本,采用浓缩法筛选寄生虫卵。结果:128名参与者中,26人(20.3%)对各种食物过敏原呈SPT阳性,16人(12.5%)有蠕虫感染。然而,食物过敏原SPT阳性和阴性学生的寄生虫感染分布相等。性别和食物过敏易感性之间也没有联系。结论:学龄期儿童食物致敏现象普遍存在,肠道蛔虫病对其患病率似乎没有影响。关键词:MPO,炎症反应,新生儿,败血症。
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Prevalence of food sensitization and helminth infection among primary school children in Ibadan, southwest Nigeria
Background : Food allergy is a problem of the western world, however, cases of food allergy have also been found in developing countries. In Nigeria, the prevalence of food allergy is scarce while the association of food sensitization with helminthiasis is unknown. Objective : This study was designed to determine the prevalence of sensitization to food among Nigerian school children and its relation to intestinal helminthiasis. Methods : A total of 128 participants were recruited from CAC Primary School, Sango, Ibadan, Nigeria. Skin Prick Test using freshly prepared food allergens was carried out. Stool samples were collected from them to screen for ova of parasites using concentration method. Results : A total of 26 (20.3%) out of 128 participants were SPT positive for various food allergens, while 16 (12.5%) had helminthic infection. There was however an equal distribution of helminthic infection among students who were food allergen SPT positive and negative. There was also no association between gender and susceptibility to food allergy. Conclusion : Sensitization to food is common in school children, and intestinal helminthiasis seems to have no influence on its prevalence. Keywords : MPO, inflammatory response, neonates, sepsis.
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