Oxidation of Mixtures of Thioureas: Part XII –Oxidation of Mixtures of 1,3-diaryl Thioureas and Thiourea Forming 1,2,4,-thiadiazolines

Oxidation of binary mixtures of 1,3-diaryl thioureas and thiourea in acidic alcoholic solution yields 3-amino-4-aryl-5-arylimino-D2-1,2,4,-thiadiazolines. The rearrangement of the bis(formamidine)sulphide to amidinothiourea derivative has been found to be governed by the steric effect. Oxidation of binary mixtures of 1-aryl-3-(2’,6’-xylyl)thiourea and thiourea in acidic alcoholic solution yields 3-amino-4-aryl-5-(2’,6’-xylyl)imino-D2-1,2,4,-thiadiazoline. 1-aryl--(2’,5’-xylyl)thiourea, and 1-aryl-3-(2’,5’-(diisopropyl phenyl)thioureas are also included in the study.