COVID-19感染患者发生肾结石的风险增加

H. Kasiri, Parisa Moradimajd, Hamidrerza Samaee, M. Ghazaeian
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摘要

背景:新型冠状病毒病(由SARS-CoV-2引起)已经成为一场世界性的灾难。根据现有证据,受这种病毒感染的主要器官是呼吸系统;然而,其他各种重要系统也可能受到潜在结果的影响。受影响最严重的器官之一是肾脏。目的:本研究旨在报道和回顾COVID-19感染患者肾结石的风险。方法:本研究通过PubMed、Scopus、Web of Science、施普林格、Ovid、谷歌Scholar等6个数据库对COVID-19患者肾结石相关文献进行综述。然后,我们报告了6例无肾脏病史和新发肾结石的成人COVID-19患者。结果:合并输尿管结石的发生率在新冠肺炎期间明显升高。有一些关于肾结石的研究,主要是关于冠状病毒感染患者肾结石的管理。然而,在6例患者中,在感染COVID-19后,患者被识别出肾结石。所有报告的患者均无肾脏疾病史或其他导致肾结石形成的危险因素。结论:肾损伤可能是冠状病毒的并发症,但根据我们的搜索,没有报告无病史的肾结石。然而,观察到的病例强调了COVID-19感染对肾功能变化的可能影响。另一方面,虽然补充维生素C和D可能有利于COVID-19的管理,但与风险相关。这些分子应谨慎使用,特别是在先前的结石形成者。医生应负责了解COVID-19的潜在治疗方法在其执业范围内对常见病理的影响。
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The Increased Risk of Renal Stones in Patients With COVID-19 Infection
Background: The novel coronavirus disease (caused by SARS-CoV-2) has become a disaster all over the world. Based on available evidence, the main organ infected by this virus is the respiratory system; however, various other vital systems can also be affected by potential outcomes. One of the critical affected organs is the kidney. Objectives: This study aimed to report and reviewed Risk of Renal Stones in Patients With COVID-19 Infection. Methods: In the present study, we reviewed literature about the renal stone in patients with COVID-19 in six databases, including PubMed, Scopus, Web of Science, Springer, Ovid, and Google Scholar. Then, we reported six adult COVID-19 patients with no history of kidney disease and new-onset renal stones. Results: The rate of complicated ureteral stone disease significantly increased during the COVID-19 period. A few studies were available about renal stones, and mostly they were about the management of renal stones in patients infected with the coronavirus. However, in six patients, after being infected with COVID-19, the renal stone was recognized in patients. All the reported patients did not have a history of renal disease or other risk factors for renal stone formation. Conclusion: Kidney injury is a possible complication of coronavirus, but based on our search, renal stone without history was not reported. However, observed cases highlighted the possible effects of COVID-19 infection on kidney function changes. On the other hand, although supplementation with vitamins C and D may be beneficial for the management of COVID-19, is associated with risks. These molecules should be used with caution, particularly in prior stone formers. Physicians should be responsible for understanding the impact of potential treatments for COVID-19 on common pathologies within their scope of practice.
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