妊娠晚期宫颈长度测量作为妊娠合并前置胎盘产前出血预测指标的有效性

M. Eid, R. Omar, Ahmed Mohamed, Khaled Abdel Maqsood
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摘要

目的:探讨宫颈长度是否可作为预测完全性前置胎盘患者产前出血、早产等围生期并发症的指标。方法:2013年10月~ 2014年4月,对30例妊娠28 ~ 36周的完全性前置胎盘患者进行经阴道宫颈长度测量。这与妊娠的临床结果相关,记录分娩时的胎龄,是否发生任何并发症,如产前出血、输血、剖腹产子宫切除术、早产和是否需要入住新生儿重症监护病房,以及剖腹产是选择性的还是在36周前因大出血而需要紧急剖腹产。结果:产前出血需紧急剖宫产17例(56.7%)。这是将患者分为两个结果组的基础:紧急CS组和选择性分娩组。通过受试者工作特征(ROC)曲线分析,我们发现28周宫颈长度≤33 mm预测产前出血需要紧急剖宫产的敏感性为88.2%,特异性为61.5%,阳性预测值为75.0%,阴性预测值为80.0%,准确率为76.7%。曲线下面积(AUC)为0.760。结论:截断值≤33mm的短宫颈长度测量可预测完全性前置胎盘患者出血及急诊剖宫产的风险增加。
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The Efficacy of Third Trimester Cervical Length Measurement as A Predictor of Ante-Partum Haemorrhage Among Pregnancies Complicated with Placenta Previa
Aim: To estimate whether the cervical length and can be used as a method to predict peripartum complications as antepartum haemorrhage and preterm delivery in cases of complete placenta previa. Methods: Between October 2013 and April 2014, transvaginal measurement of cervical length was done for 30 cases of complete placenta previa identified between 28 weeks and 36 weeks of gestation. This was correlated to the clinical outcome of pregnancy with recordings for the gestational age at time of delivery, occurrence if any complications as antepartum haemorrhage ,blood transfusion, caesarean hysterectomy , preterm delivery and the need for NICU admission and whether the caesarean section was elective or emergency caesarean section was needed before 36 weeks due to massive haemorrhage. Results: Antepartum haemorrhage necessitating emergency cesarean section was observed in 17 patients (56.7%). This was the basis of grouping the patients into two outcome groups: Emergency CS group and elective delivery group. Using receiver-operating characteristic (ROC) curve analysis we found that a cervical length ≤ 33 mm at 28 weeks was predictive of antepartum haemorrhage necessitating emergency caesarean section with a sensitivity of 88.2% and specificity of 61.5% positive predictive value of 75.0% and negative predicative value of 80.0% and accuracy of 76.7%. Area under the curve (AUC) was 0.760. with P-value < 0.01 Conclusion: Short cervical length measurements at cut-off value ≤33mm may predict increased risk of hemorrhage and emergency caesarean section in patients with complete placenta previa.
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