{"title":"用集成光波导传感器测定血红蛋白衍生物的吸收系数","authors":"Shin-Won Kang, K. Sasaki, H. Minamitani","doi":"10.1109/IEMBS.1992.5760911","DOIUrl":null,"url":null,"abstract":"A simple method of determining the absorption coefficient of absorbing aqueous biochemicals is proposed as an application of the complex propagation constant of guided wave in a thin-film optical waveguide. It was designed to consecutively change the interaction length between the evanescent field and the sample, and evaluated by prism couplers. The response linearly depends on the interaction length and the total hemoglobin concentration (THb) of hemoglobin derivatives. The determined absorption coefficients fairly well coincide with the values obtained by the conventional transmission measurement.","PeriodicalId":6457,"journal":{"name":"1992 14th Annual International Conference of the IEEE Engineering in Medicine and Biology Society","volume":"39 1","pages":"171-172"},"PeriodicalIF":0.0000,"publicationDate":"1992-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":"{\"title\":\"Determining the absorption coefficient of hemoglobin derivatives with integrated optic waveguide sensor\",\"authors\":\"Shin-Won Kang, K. Sasaki, H. Minamitani\",\"doi\":\"10.1109/IEMBS.1992.5760911\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"A simple method of determining the absorption coefficient of absorbing aqueous biochemicals is proposed as an application of the complex propagation constant of guided wave in a thin-film optical waveguide. It was designed to consecutively change the interaction length between the evanescent field and the sample, and evaluated by prism couplers. The response linearly depends on the interaction length and the total hemoglobin concentration (THb) of hemoglobin derivatives. The determined absorption coefficients fairly well coincide with the values obtained by the conventional transmission measurement.\",\"PeriodicalId\":6457,\"journal\":{\"name\":\"1992 14th Annual International Conference of the IEEE Engineering in Medicine and Biology Society\",\"volume\":\"39 1\",\"pages\":\"171-172\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1992-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"1992 14th Annual International Conference of the IEEE Engineering in Medicine and Biology Society\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/IEMBS.1992.5760911\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"1992 14th Annual International Conference of the IEEE Engineering in Medicine and Biology Society","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/IEMBS.1992.5760911","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Determining the absorption coefficient of hemoglobin derivatives with integrated optic waveguide sensor
A simple method of determining the absorption coefficient of absorbing aqueous biochemicals is proposed as an application of the complex propagation constant of guided wave in a thin-film optical waveguide. It was designed to consecutively change the interaction length between the evanescent field and the sample, and evaluated by prism couplers. The response linearly depends on the interaction length and the total hemoglobin concentration (THb) of hemoglobin derivatives. The determined absorption coefficients fairly well coincide with the values obtained by the conventional transmission measurement.
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