神经肌肉连接处的突触间隙

Joshua R. Sanes
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引用次数: 34

摘要

包住每条骨骼肌纤维的基底膜(BL)在神经肌肉连接处的突触前膜和突触后膜之间穿过。这种排列的结果是,BL包含了该突触的大部分突触间隙物质。一些指导突触前和突触后成分分化和再生的线索与突触BL稳定相关。本文综述了旨在识别这些成分并了解它们如何工作的研究。
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The synaptic cleft of the neuromuscular junction

The basal lamina (BL) that ensheaths each skeletal musclefiber passes between the pre- and postsynaptic membranes at the neuromuscular junction. A consequence of this arrangement is that BL comprises much of the synaptic cleft material of this synapse. Some of the cues that guide differentiation and regeneration of both pre- and postsynaptic components are stably associated with synaptic BL. This paper reviews studies aimed at identifying these components and learning how they work.

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