子宫内膜异位瘤的治疗现状

Mohamed Aboulghar, Ragaa Mansour
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引用次数: 2

摘要

有充分的证据表明,没有成功的医学治疗卵巢子宫内膜异位瘤。经阴道误吸与复发率非常高有关。使用四环素和乙醇等硬化剂可降低复发率,但误吸可能导致感染或粘连。手术治疗子宫内膜异位瘤是治疗相关疼痛的合适方法。腹腔镜手术治疗子宫内膜异位瘤优于剖腹手术,因其术后疼痛少、出血量少、住院时间短。人们认为,对囊肿壁的浅表子宫内膜进行凝固和消融是一种有效的治疗方法,因为它对卵巢组织的损害可能最小。卵巢囊肿切除术被认为是更有效的治疗方法,且复发率较低。然而,尚无可用的随机研究来比较两种治疗不孕症的方式。如果输卵管通畅,可以尝试卵巢刺激和宫内人工授精的辅助生殖,在广泛粘连或手术治疗失败后,IVF被认为是第一线治疗。
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Current status of management of endometriomas

It is well documented that there is no successful medical treatment for ovarian endometriomas. Transvaginal aspiration is associated with a very high recurrence rate. The use of sclerosing agents as tetracycline and ethanol may reduce the recurrence rate, however, aspiration may possibly result in infection or adhesions.

Surgical treatment of endometriomas is the appropriate approach in the management of associated pain. Laparoscopic surgery proved to be superior to laparotomy in the treatment of endometriomas as it showed less postoperative pain, less blood loss and shorter hospital stay. It is believed that coagulation and ablation of the superficial endometrium lining of the cyst wall is an effective line of treatment as it causes the minimal possible damage to the ovarian tissue. Ovarian cystectomy is considered to be more effective treatment and is associated with lower incidence of recurrence rate. However, there is no available randomized studies to compare both modalities concerning infertility treatment. Assisted reproduction in the form of ovarian stimulation and intrauterine insemination could be tried if the tubes are patent, and IVF is considered as the first line of treatment in extensive adhesions or after failure of surgical treatment.

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