细胞内微电极阵列部分封装垂直纳米电极的制备

Sonja Allani, A. Jupe, H. Kappert, H. Vogt
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引用次数: 0

摘要

在这项工作中,提出了一个关于垂直纳米电极制造技术的概念和原理证明。设计了一种与cmos兼容的三维管制造工艺,该三维管部分被绝缘层封装。提出了一种基于深度反应离子刻蚀(DRIE)和原子层沉积(ALD)的扩展牺牲层技术。另外间距技术的电极直径锥形和尖端后光刻进行了研究。最后,制作了独立的纳米电极和测试结构。由此产生的可调谐纳米电极阵列可用于集成电路和活细胞之间的双向接口。
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Fabrication of Partly Encapsulated Vertical Nanoelectrodes for an Intracellular Microelectrode Array
In this work, a concept and proof of principle regarding a fabrication technique for vertical nanoelectrodes is presented. CMOS-compatible processes for the fabrication of three-dimensional tubes which are partly encapsulated by an insulation layer are conceived. An extended sacrificial layer technique using deep reactive ion etching (DRIE) and atomic layer deposition (ALD) of encapsulation and electrode material was developed. Additional spacing techniques for tapering of electrode diameter and tip post-lithographically are investigated. Finally, free-standing nanoelectrodes and test structures were produced. The resulting tunable nanoelectrode array can lead to a novel device for a bidirectional interface between integrated circuits and living cells.
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