抗利尿激素和催产素受体在GtoPdb .2023.1

D. Bichet, Michel Bouvier, B. Chini, G. Gimpl, G. Guillon, Tadashi Kimura, M. Knepper, S. Lolait, M. Manning, B. Mouillac, A. O'Carroll, C. Serradeil‐Le Gal, M. Soloff, J. Verbalis, M. Wheatley, H. Zingg
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引用次数: 0

摘要

抗利尿激素(AVP)和催产素(OT)受体(命名由NC-IUPHAR推荐[94])被内源性环非肽抗利尿激素和催产素激活。这些多肽来源于前体,这些前体也产生神经physin(神经physin I为催产素;抗利尿激素(neurophysin II)。加压素和催产素仅在2个氨基酸(位置3和8)上存在差异。这些神经肽的代谢物可能具有生物活性[69]。
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Vasopressin and oxytocin receptors in GtoPdb v.2023.1
Vasopressin (AVP) and oxytocin (OT) receptors (nomenclature as recommended by NC-IUPHAR [94]) are activated by the endogenous cyclic nonapeptides vasopressin and oxytocin. These peptides are derived from precursors which also produce neurophysins (neurophysin I for oxytocin; neurophysin II for vasopressin). Vasopressin and oxytocin differ at only 2 amino acids (positions 3 and 8). There are metabolites of these neuropeptides that may be biologically active [69].
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