壳聚糖纳米颗粒在生物医学上的应用

Khairujjaman Laskar, A. Rauf
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引用次数: 9

摘要

本文综述了近年来壳聚糖基纳米颗粒的生物应用。在过去的十年中,生物聚合物基材料因其生物相容性、可生物降解、无毒和无过敏性而受到广泛关注。本文综述了近年来壳聚糖纳米颗粒在癌症治疗和生物医学方面的研究进展。概述了壳聚糖及其衍生物和壳聚糖纳米颗粒的形成,以及壳聚糖固有的和特定的治疗功效。综述了药物传递途径、基因传递途径以及组织工程应用方面的主要进展。
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Chitosan Based Nanoparticles towards Biomedical Applications
This review outlines the bioapplications of newly developed chitosan based nanoparticles. Over the last decade, much interest has been developed in biopolymer based materials due to their biocompatible, biodegradable, nontoxic and non-allergenic nature. Here, we review the recent scientific advances in chitosan based nanoparticles not only for cancer therapy but also for various biomedical applications. An overview of chitosan, its derivatives and the formation of chitosan nanoparticles is provided along with the inherent and specific therapeutic efficacy. Major progresses in drug delivery approaches and gene delivery as well as tissue engineering applications have been summarized.
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