逆行性遗忘的机制:以生物胺为例

Perry Kurtz , Tibor Palfai
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引用次数: 9

摘要

对各种治疗产生逆行性遗忘的机制的研究解释大致有三种类型:(1)中枢神经系统兴奋性的普遍改变;(2)脑蛋白或RNA合成速率的改变;(3)脑神经递质水平的改变。在这里,我们回顾了这些解释,并在Kety模型的框架内提出,在记忆存储的关键时期,正常水平的生物胺可能对保持记忆至关重要。
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Mechanisms in retrograde amnesia: a case for biogenic amines

Research interpretations of the mechanisms by which various treatments produce retrograde amnesia are of three general types: (1) general modification of central nervous system excitability, (2) changes in the rate of brain protein or RNA synthesis, (3) alterations of brain neurotransmitter levels. Here, we review these interpretations and, within the framework of Kety's model, suggest that normal levels of biogenic amines during a critical period of memory storage may be essential for retention.

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