晚期硬化苔藓导致完全唇融合和尿潴留的绝经后患者

Erich T. Wyckoff, D. Schweer, Girard M. Cua
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引用次数: 0

摘要

硬化地衣是一种病因不明的良性慢性皮肤病,主要影响生殖器。主要的治疗方法是局部使用高效皮质类固醇。虽然是良性的,但它是进行性的,在疾病的晚期,可导致严重的功能损害,需要手术治疗。我们报告了一例晚期硬化地衣导致完全唇融合和梗阻性尿潴留需要手术干预的病例。我们也进行了文献回顾类似的地衣硬化的情况下。一个71岁的病人被转介到妇科外科,从他们的泌尿科医生评估完全唇融合与相关的尿潴留。成功完成外阴成形术。术后,她开始每天使用雌二醇乳膏,以帮助伤口初步愈合。19天后,阴道保持通畅并正常愈合。4个月后,她成功滴注氯倍他索,每周两次,无症状复发。除了成功的手术干预外,本病例说明需要经常随访和维持治疗以防止复发。
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Advanced Lichen Sclerosus Resulting in Complete Labial Fusion and Urinary Retention in a Postmenopausal Patient
Lichen sclerosus is a benign, chronic dermatological condition of unknown etiology that primarily affects the genitalia. The mainstay of therapy is a topical high-potency corticosteroid. Although benign, it is progressive and, in advanced stage disease, can lead to severe functional impairment requiring surgical management. We present a case of advanced lichen sclerosus that resulted in complete labial fusion and obstructive urinary retention requiring surgical intervention. We also performed a review of the literature on similar lichen sclerosus cases. A 71-yearold patient was referred to gynecologic surgery from their urologist for evaluation of complete labial fusion with associated urinary retention. A vulvoperineoplasty was successfully performed. Postoperatively, she was started on estradiol cream daily to assist with initial wound healing. After 19 days, the vagina remained patent and was healing properly. Four months later, she was successfully titrated to twice weekly dosing of clobetasol without recurrence of symptoms. In addition to successful surgical intervention, this case illustrates the need for frequent follow-up and maintenance therapy to prevent relapse.
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