COVID-19大流行期间加快产后出院和急性产后护理利用

A. Panzer, Anne E. Reed-Weston, A. Friedman, D. Goffman, T. Wen
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Methods This retrospective cohort study evaluated birth hospitalizations at affiliated hospitals during two periods: (i) the apex of the ‘first wave’ of the COVID-19 pandemic in New York City (3/22/20 to 4/30/20) and (ii) a historical control period of one year earlier (3/22/19 to 4/30/19). Routine postpartum discharge was defined as ≥2 d after vaginal birth and ≥3 d after cesarean birth. Expedited discharge was defined as <2 d after vaginal birth and <3 d after cesarean birth. Acute postpartum care utilization was defined as any emergency room visit, obstetric triage visit, or postpartum readmission ≤6 weeks after birth hospitalization discharge. Demographic and clinical variables were compared based on routine versus expedited postpartum discharge. Unadjusted and adjusted logistic regression models were performed to analyze factors associated with (i) expedited discharge and (ii) acute postpartum care utilization. Unadjusted (ORs) and adjusted odds ratios (aORs) with 95% CIs were used as measures of association. Stratified analysis was performed restricted to patients with chronic hypertension, preeclampsia, and gestational hypertension. Results A total of 1,358 birth hospitalizations were included in the analysis, 715 (52.7%) from 2019 and 643 (47.3%) from 2020. Expedited discharge was more common in 2020 than in 2019 (60.3% versus 5.0% of deliveries, p < .01). For 2020, clinical factors significantly associated with a decreased likelihood of expedited discharge included hypertensive disorders of pregnancy (OR 0.40, 95% CI 0.27–0.60), chronic hypertension (OR 0.14, 95% CI 0.06–0.29), and COVID-19 infection (OR 0.51, 95% CI 0.34–0.77). Cesarean (OR 3.00, 95% CI 2.14–4.19) and term birth (OR 3.34, 95% CI 2.03, 5.49) were associated with an increased likelihood of expedited discharge. Most of the associations retained significance in adjusted models. Expedited compared to routine discharge was not associated with significantly different odds of acute postpartum care utilization for 2020 deliveries (5.4% versus 5.9%; OR 0.92, 95% CI 0.47–1.82). Medicaid insurance (OR 2.30, 95% CI 1.06–4.98) and HDP (OR 5.16, 95% CI: 2.60–10.26) were associated with a higher risk of acute postpartum care utilization and retained significance in adjusted analyses. In the stratified analysis restricted to women with hypertensive diagnoses, expedited discharge was associated with significantly increased risk for postpartum readmission (OR 6.09, 95% CI 2.14, 17.33) but not overall acute postpartum care utilization (OR 2.17, 95% CI 1.00, 4.74). Conclusion Expedited postpartum discharge was not associated with increased risk for acute postpartum care utilization. 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引用次数: 2

摘要

背景新冠肺炎大流行期间,产后早期出院人数有机增加。目前尚不清楚这种缩短产后住院时间的“自然实验”是否会增加产后再入院和其他急性产后护理的风险,如急诊室就诊。目的本研究的目的是确定哪些临床因素与产后加速出院有关,以及产后加速出院是否与急性产后护理使用风险增加有关。方法本回顾性队列研究评估了两个时期附属医院的出生住院情况:(i)纽约市COVID-19大流行“第一波”高峰期(20年3月22日至20年4月30日)和(ii)一年前的历史对照期(19年3月22日至19年4月30日)。产后常规出院定义为阴道分娩后≥2天,剖宫产后≥3天。加速出院定义为阴道分娩后<2天,剖宫产后<3天。急性产后护理利用被定义为任何急诊室就诊,产科分诊就诊,或产后再入院≤出生后6周住院出院。人口统计学和临床变量基于常规和加速产后出院进行比较。采用未调整和调整的logistic回归模型来分析与(i)加速出院和(ii)急性产后护理利用相关的因素。采用95% ci的未校正(ORs)和校正优势比(aORs)作为相关性的衡量标准。分层分析仅限于慢性高血压、先兆子痫和妊娠期高血压患者。结果共纳入1358例分娩住院病例,其中2019年715例(52.7%),2020年643例(47.3%)。2020年加速分娩比2019年更常见(60.3%比5.0%,p < 0.01)。2020年,与加速出院可能性降低显著相关的临床因素包括妊娠高血压疾病(OR 0.40, 95% CI 0.27-0.60)、慢性高血压(OR 0.14, 95% CI 0.06-0.29)和COVID-19感染(OR 0.51, 95% CI 0.34-0.77)。剖宫产(OR 3.00, 95% CI 2.14-4.19)和足月分娩(OR 3.34, 95% CI 2.03, 5.49)与加速出院的可能性增加相关。大多数关联在调整后的模型中保持显著性。与常规分娩相比,加速分娩在2020年分娩时使用急性产后护理的几率没有显著差异(5.4%对5.9%;或0.92,95% ci 0.47-1.82)。医疗补助保险(OR 2.30, 95% CI 1.06-4.98)和HDP (OR 5.16, 95% CI: 2.60-10.26)与急性产后护理使用的高风险相关,在调整分析中仍具有显著性。在仅限于诊断为高血压的妇女的分层分析中,加速出院与产后再入院风险显著增加相关(OR 6.09, 95% CI 2.14, 17.33),但与总体急性产后护理利用率无关(OR 2.17, 95% CI 1.00, 4.74)。结论加速产后出院与急性产后护理使用风险增加无关。在诊断为高血压的妇女中,加速出院与再入院的高风险相关,尽管加速出院发生的频率较低。
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Expedited postpartum discharge during the COVID-19 pandemic and acute postpartum care utilization
Abstract Background Early postpartum discharges increased organically during the COVID-19 pandemic. It is not known if this ‘natural experiment’ of shorter postpartum hospital stays resulted in increased risk for postpartum readmissions and other acute postpartum care utilization such as emergency room encounters. Objective The objectives of this study were to determine which clinical factors were associated with expedited postpartum discharge and whether the expedited postpartum discharge was associated with increased risk for acute postpartum care utilization. Methods This retrospective cohort study evaluated birth hospitalizations at affiliated hospitals during two periods: (i) the apex of the ‘first wave’ of the COVID-19 pandemic in New York City (3/22/20 to 4/30/20) and (ii) a historical control period of one year earlier (3/22/19 to 4/30/19). Routine postpartum discharge was defined as ≥2 d after vaginal birth and ≥3 d after cesarean birth. Expedited discharge was defined as <2 d after vaginal birth and <3 d after cesarean birth. Acute postpartum care utilization was defined as any emergency room visit, obstetric triage visit, or postpartum readmission ≤6 weeks after birth hospitalization discharge. Demographic and clinical variables were compared based on routine versus expedited postpartum discharge. Unadjusted and adjusted logistic regression models were performed to analyze factors associated with (i) expedited discharge and (ii) acute postpartum care utilization. Unadjusted (ORs) and adjusted odds ratios (aORs) with 95% CIs were used as measures of association. Stratified analysis was performed restricted to patients with chronic hypertension, preeclampsia, and gestational hypertension. Results A total of 1,358 birth hospitalizations were included in the analysis, 715 (52.7%) from 2019 and 643 (47.3%) from 2020. Expedited discharge was more common in 2020 than in 2019 (60.3% versus 5.0% of deliveries, p < .01). For 2020, clinical factors significantly associated with a decreased likelihood of expedited discharge included hypertensive disorders of pregnancy (OR 0.40, 95% CI 0.27–0.60), chronic hypertension (OR 0.14, 95% CI 0.06–0.29), and COVID-19 infection (OR 0.51, 95% CI 0.34–0.77). Cesarean (OR 3.00, 95% CI 2.14–4.19) and term birth (OR 3.34, 95% CI 2.03, 5.49) were associated with an increased likelihood of expedited discharge. Most of the associations retained significance in adjusted models. Expedited compared to routine discharge was not associated with significantly different odds of acute postpartum care utilization for 2020 deliveries (5.4% versus 5.9%; OR 0.92, 95% CI 0.47–1.82). Medicaid insurance (OR 2.30, 95% CI 1.06–4.98) and HDP (OR 5.16, 95% CI: 2.60–10.26) were associated with a higher risk of acute postpartum care utilization and retained significance in adjusted analyses. In the stratified analysis restricted to women with hypertensive diagnoses, expedited discharge was associated with significantly increased risk for postpartum readmission (OR 6.09, 95% CI 2.14, 17.33) but not overall acute postpartum care utilization (OR 2.17, 95% CI 1.00, 4.74). Conclusion Expedited postpartum discharge was not associated with increased risk for acute postpartum care utilization. Among women with hypertensive diagnoses, expedited discharge was associated with a higher risk for readmission despite expedited discharge occurring less frequently.
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