Ghaneya S. Hassan, Hanan H. Georgey, Riham F. George, Eman R. Mohamed
{"title":"Aurones和furouronones:生物活性和合成","authors":"Ghaneya S. Hassan, Hanan H. Georgey, Riham F. George, Eman R. Mohamed","doi":"10.1016/j.bfopcu.2018.06.002","DOIUrl":null,"url":null,"abstract":"<div><p>Aurones, (<em>Z</em>)-2-benzylidenebenzofuran-3(2<em>H</em>)-ones, have proved to be promising bioactive compounds with a broad spectrum of activities including anticancer, antioxidant, antiparasitic and antibacterial activities. Aurones exhibited strong antiproliferative properties against cancer cells by acting on variable targets through different modes of action. Furoaurones, (<em>Z</em>)-2-benzylidenefurano[3,2-f] benzofuran-3(2<em>H</em>)-ones, is a class of semi synthetic compounds derived from naturally furanochromones extracted from of <em>Ammi visnaga</em> (L.) fruits. So, this literature review includes different biological activities of aurones and furoaurones and different methods for their synthesis.</p></div>","PeriodicalId":9369,"journal":{"name":"Bulletin of Faculty of Pharmacy, Cairo University","volume":"56 2","pages":"Pages 121-127"},"PeriodicalIF":0.0000,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.bfopcu.2018.06.002","citationCount":"19","resultStr":"{\"title\":\"Aurones and furoaurones: Biological activities and synthesis\",\"authors\":\"Ghaneya S. Hassan, Hanan H. Georgey, Riham F. George, Eman R. Mohamed\",\"doi\":\"10.1016/j.bfopcu.2018.06.002\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Aurones, (<em>Z</em>)-2-benzylidenebenzofuran-3(2<em>H</em>)-ones, have proved to be promising bioactive compounds with a broad spectrum of activities including anticancer, antioxidant, antiparasitic and antibacterial activities. Aurones exhibited strong antiproliferative properties against cancer cells by acting on variable targets through different modes of action. Furoaurones, (<em>Z</em>)-2-benzylidenefurano[3,2-f] benzofuran-3(2<em>H</em>)-ones, is a class of semi synthetic compounds derived from naturally furanochromones extracted from of <em>Ammi visnaga</em> (L.) fruits. So, this literature review includes different biological activities of aurones and furoaurones and different methods for their synthesis.</p></div>\",\"PeriodicalId\":9369,\"journal\":{\"name\":\"Bulletin of Faculty of Pharmacy, Cairo University\",\"volume\":\"56 2\",\"pages\":\"Pages 121-127\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2018-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/j.bfopcu.2018.06.002\",\"citationCount\":\"19\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Bulletin of Faculty of Pharmacy, Cairo University\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1110093118300267\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bulletin of Faculty of Pharmacy, Cairo University","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1110093118300267","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Aurones and furoaurones: Biological activities and synthesis
Aurones, (Z)-2-benzylidenebenzofuran-3(2H)-ones, have proved to be promising bioactive compounds with a broad spectrum of activities including anticancer, antioxidant, antiparasitic and antibacterial activities. Aurones exhibited strong antiproliferative properties against cancer cells by acting on variable targets through different modes of action. Furoaurones, (Z)-2-benzylidenefurano[3,2-f] benzofuran-3(2H)-ones, is a class of semi synthetic compounds derived from naturally furanochromones extracted from of Ammi visnaga (L.) fruits. So, this literature review includes different biological activities of aurones and furoaurones and different methods for their synthesis.