在重症监护室治疗与苯妥英相关的中毒性表皮坏死松解的牙科管理:病例报告

Carolina Ruppel, Nathália Christina Stremel Martins, Marceli Dias Ferreira, Larissa Camargo, M. Claudino, E. Campagnoli
{"title":"在重症监护室治疗与苯妥英相关的中毒性表皮坏死松解的牙科管理:病例报告","authors":"Carolina Ruppel, Nathália Christina Stremel Martins, Marceli Dias Ferreira, Larissa Camargo, M. Claudino, E. Campagnoli","doi":"10.1590/1981-86372022000920200108","DOIUrl":null,"url":null,"abstract":"ABSTRACT Stevens-Johnson syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) are adverse reactions, usually medicine-related, in which extensive and painful mucocutaneous lesions are formed. Oral lesions are characterized by the presence of erosions and ulcers. The treatment usually requires intensive care in a hospital setting, where the Dentist is essential in the multidisciplinary team, as he will act in the treatment of oral lesions. In this article, a 26-year-old female patient was reported, who presented TEN-compatible mucocutaneous lesions associated with the drug Phenytoin and required admission to a Teaching Hospital. The treatment consisted of the immediate suspension of the Phenytoin use and systemic therapy with corticosteroids and immunosuppressants. Oral lesions were monitored by the hospital dentistry team. The procedures adopted were: oral hygiene with 0.12% non-alcoholic Chlorhexidine Digluconate solution, hydration of the oral tissue with an essential fatty acid, application of frozen chamomile tea, and prescription of topical Triamcinolone Acetonide. Also, low-level laser therapy sessions (red and infrared) were performed. Oral lesions evolved with significant improvement. In this case, the importance of the Dentist in the multi-professional team is demonstrated. Although there is no protocol, the procedures used in the present case can be an alternative to therapies used in SSJ and TEN oral lesions.","PeriodicalId":30069,"journal":{"name":"RGO Revista Gaucha de Odontologia","volume":"181 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Dental management in the Intensive Care Unit in the treatment of toxic epidermal necrolysis associated with phenytoin: case report\",\"authors\":\"Carolina Ruppel, Nathália Christina Stremel Martins, Marceli Dias Ferreira, Larissa Camargo, M. Claudino, E. Campagnoli\",\"doi\":\"10.1590/1981-86372022000920200108\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"ABSTRACT Stevens-Johnson syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) are adverse reactions, usually medicine-related, in which extensive and painful mucocutaneous lesions are formed. Oral lesions are characterized by the presence of erosions and ulcers. The treatment usually requires intensive care in a hospital setting, where the Dentist is essential in the multidisciplinary team, as he will act in the treatment of oral lesions. In this article, a 26-year-old female patient was reported, who presented TEN-compatible mucocutaneous lesions associated with the drug Phenytoin and required admission to a Teaching Hospital. The treatment consisted of the immediate suspension of the Phenytoin use and systemic therapy with corticosteroids and immunosuppressants. Oral lesions were monitored by the hospital dentistry team. The procedures adopted were: oral hygiene with 0.12% non-alcoholic Chlorhexidine Digluconate solution, hydration of the oral tissue with an essential fatty acid, application of frozen chamomile tea, and prescription of topical Triamcinolone Acetonide. Also, low-level laser therapy sessions (red and infrared) were performed. Oral lesions evolved with significant improvement. In this case, the importance of the Dentist in the multi-professional team is demonstrated. Although there is no protocol, the procedures used in the present case can be an alternative to therapies used in SSJ and TEN oral lesions.\",\"PeriodicalId\":30069,\"journal\":{\"name\":\"RGO Revista Gaucha de Odontologia\",\"volume\":\"181 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"RGO Revista Gaucha de Odontologia\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1590/1981-86372022000920200108\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"RGO Revista Gaucha de Odontologia","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1590/1981-86372022000920200108","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

史蒂文斯-约翰逊综合征(SJS)和中毒性表皮坏死松解(TEN)是一种不良反应,通常与药物相关,形成广泛和疼痛的皮肤粘膜病变。口腔病变的特点是存在糜烂和溃疡。治疗通常需要在医院进行重症监护,牙医在多学科团队中至关重要,因为他将治疗口腔病变。在这篇文章中,我们报道了一位26岁的女性患者,她出现了与苯妥英相关的ten相容的皮肤粘膜病变,并要求住进教学医院。治疗包括立即停用苯妥英,并用皮质类固醇和免疫抑制剂进行全身治疗。口腔病变由医院牙科小组监测。采用的方法是:用0.12%的非酒精双露酸氯己定溶液进行口腔卫生,用必需脂肪酸水化口腔组织,应用冷冻洋甘菊茶,外用曲安奈德处方。此外,还进行了低水平激光治疗(红色和红外线)。口腔病变进展明显改善。在这种情况下,牙医在多专业团队中的重要性得到了证明。虽然没有协议,但本病例中使用的程序可以替代用于SSJ和TEN口腔病变的治疗方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Dental management in the Intensive Care Unit in the treatment of toxic epidermal necrolysis associated with phenytoin: case report
ABSTRACT Stevens-Johnson syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) are adverse reactions, usually medicine-related, in which extensive and painful mucocutaneous lesions are formed. Oral lesions are characterized by the presence of erosions and ulcers. The treatment usually requires intensive care in a hospital setting, where the Dentist is essential in the multidisciplinary team, as he will act in the treatment of oral lesions. In this article, a 26-year-old female patient was reported, who presented TEN-compatible mucocutaneous lesions associated with the drug Phenytoin and required admission to a Teaching Hospital. The treatment consisted of the immediate suspension of the Phenytoin use and systemic therapy with corticosteroids and immunosuppressants. Oral lesions were monitored by the hospital dentistry team. The procedures adopted were: oral hygiene with 0.12% non-alcoholic Chlorhexidine Digluconate solution, hydration of the oral tissue with an essential fatty acid, application of frozen chamomile tea, and prescription of topical Triamcinolone Acetonide. Also, low-level laser therapy sessions (red and infrared) were performed. Oral lesions evolved with significant improvement. In this case, the importance of the Dentist in the multi-professional team is demonstrated. Although there is no protocol, the procedures used in the present case can be an alternative to therapies used in SSJ and TEN oral lesions.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
35
审稿时长
20 weeks
期刊最新文献
Sleep disorders are associated with both morning temporal and jaw pain among adults and elderly: a population-based study in Brazil Radiolucent image in lower third molar: hidden caries or pre-eruptive resorption?: a case report Edentulism and number of medications are associated with nutritional status in older adults: a population-based cross-sectional study Fluoride in Mozambique: retrospective study Evidence-practice gap in treatment recommendations for proximal caries among Brazilian dentists
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1