U-Net for Multi-Organ Segmentation of SPECT Projection Data

In this work we investigate the usage of deep learning techniques on SPECT data solving a multi-organ segmentation problem. We extract projections from 21 Lu-177 MELP SPECT scans and obtain the corresponding ground truth labels from the accompanied CT scans by forward-projection of 3D CT organ segmentations. We train a U-Net to predict the area of the kidney, spleen, liver, and background seen in the projection data, using a weighted dice loss between prediction and target labels to account for class imbalance. With our method we achieved a mean dice coefficient of 72 % on the test set, encouraging us to perform further experiments using the U-Net.