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2020 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)最新文献

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First Principle Defect Analysis in 150 µm 4H-SiC Epitaxial Layer Schottky Barrier Detectors 150µm 4H-SiC外延层肖特基势垒探测器的第一原理缺陷分析
Pub Date : 2020-10-31 DOI: 10.1109/NSS/MIC42677.2020.9507936
Joshua W. Kleppinger, S. Chaudhuri, Omerfaruk Karadavut, K. Mandal
High resolution Schottky barrier detectors (SBDs) were fabricated on 150 µm thick 4H-SiC epilayers using a proprietary device design. Electrical properties of the SBD junctions were characterized by temperature-dependent current-voltage (I-V- T) measurements which showed ultra-low leakage current densities lower than 100 pA cm−2at -150 V and remained below 1 µ A.cm−2 even at 600K. Electrically active deep levels present in the epilayers were identified and characterized by deep level transient spectroscopy (DLTS) which showed the presence of three deep levels - Ti(c), Z1/2 and EH6/7- with low concentrations (~1011 cm−3). The energy levels were investigated theoretically by density functional theory (DFT) calculations on intrinsic vacancies and titanium point defects. Pulse height spectra (PHS) were collected using a 241Am alpha source and a percentage energy resolution of 0.55% at 5486 keV was obtained. Further analysis of the forward bias I-V- T showed an improvement in ideality factor and barrier height at elevated temperature revealing the improvement of detection performance at higher temperature.
采用专有器件设计,在150µm厚的4H-SiC薄膜上制备了高分辨率肖特基势垒探测器(sdd)。通过温度相关的电流-电压(I-V- T)测量表征了SBD结的电学特性,结果表明,在-150 V时,泄漏电流密度低于100 pA cm - 2,即使在600K时也保持在1µa cm - 2以下。利用深能级瞬态光谱(deep level transient spectroscopy, dts)对脱膜中存在的电活性能级进行了鉴定和表征,发现存在3个低浓度(~1011 cm−3)的深能级Ti(c)、Z1/2和EH6/7。利用密度泛函理论(DFT)计算了本征空位和钛点缺陷的能级。采用241Am α源采集了脉冲高度光谱(PHS),在5486 keV下获得了0.55%的百分比能量分辨率。进一步分析正向偏压I-V- T,发现理想因子和势垒高度在高温下有所提高,表明在高温下检测性能有所提高。
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引用次数: 0
ALTIROC 1, a 25 ps time resolution ASIC for the ATLAS High Granularity Timing Detector ALTIROC 1,用于ATLAS高粒度定时检测器的25 ps时间分辨率ASIC
Pub Date : 2020-10-31 DOI: 10.1109/NSS/MIC42677.2020.9507972
C. Agapopoulou, P. Dinaucourt, A. Dragone, D. Gong, C. de La Taille, N. Makovec, B. Markovic, G. Martin-Chassard, C. Milke, M. Morenas, L. Ruckman, S. Sacerdoti, A. Schwartzman, N. Seguin-Moreau, L. Serin, D. Su, J. Ye
1 Abstract—Designed and characterized by the HGTD collaboration, ALTIROC belongs to the family of readout ASICs used at the Large Hadron Collider (LHC) for the High Luminosity-LHC upgrade. ALTIROC1 is a 25-channel ASIC designed in CMOS 130 nm to read out the 5 x 5 matrix of 1.3 mm x 1.3 mm Low Gain Avalanche Diodes (LGAD) of the ATLAS HGTD detector. The targeted combined time resolution of the sensor and its readout electronics from 35 ps/hit (initial) to 70 ps/hit (end of operational lifetime). Each ASIC channel integrates an RF preamplifier followed by a high speed discriminator and two TDCs for Time-of-Arrival and Time-Over-Threshold measurements as well as a local memory. This front-end must exhibit an extremely low jitter noise while keeping a challenging power consumption of less than 4.5 mW per channel. This conference proceeding summarizes the ASIC's architecture, its measured performances compared to simulation, along with the requirements for the HEP experiments.
摘要:ALTIROC由HGTD合作设计和表征,属于大型强子对撞机(LHC)用于高亮度-LHC升级的读出asic家族。ALTIROC1是一款采用CMOS 130 nm设计的25通道ASIC,用于读取ATLAS HGTD探测器的1.3 mm x 1.3 mm低增益雪崩二极管(LGAD)的5 x 5矩阵。传感器及其读出电子器件的目标组合时间分辨率从35ps /命中(初始)到70ps /命中(运行寿命结束)。每个ASIC通道集成了一个RF前置放大器,随后是一个高速鉴别器和两个tdc,用于到达时间和超过阈值的测量,以及一个本地存储器。该前端必须具有极低的抖动噪声,同时保持每个通道低于4.5 mW的具有挑战性的功耗。本次会议总结了ASIC的架构,与仿真相比的测量性能,以及HEP实验的要求。
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引用次数: 6
Deconvolving Plastic Scintillator Gamma-Ray Spectra Using Particle Swarm Optimization 基于粒子群优化的塑料闪烁体伽玛射线谱解卷积
Pub Date : 2020-10-31 DOI: 10.1109/NSS/MIC42677.2020.9507902
A. Proctor
Plastic scintillators made from Polyvinyl Toluene 1(PVT) doped with fluorescent dye are used extensively in homeland security, scrap metal inspections, and other applications that require a large-area, cost-effective gamma detector. Unfortunately, gamma ray detection with PVT results in only Compton-edge events which contribute to a broad continuum spectrum having no discernible features. Other methods of obtaining information from low resolution PVT spectra have been described in publications but at the present time there is no practical method suitable for routine use. We have developed a method based on Particle Swarm Optimization (PSO) which analyzes raw PVT spectra and provides a histogram of contribution(s) vs. incident monoenergetic gamma energy(s). This is accomplished by summing multiple single-energy calculated PVT gamma responses into a ‘spectrum’ until a ‘best fit’ to the original raw data spectrum is obtained. The input set of response functions are calculated using MCNP5 and cover an appropriate energy range; we use a set of 255 response functions with 11 keV spacing between them (this corresponds to the ADC gain used in our PVT detectors). This set provides a range of 11 keV to 2805 keV for incident monoenergetic gamma energies which is suitable for most applications. Usually, we find that only one or two gamma response functions contribute to a ‘peak’ in the calculated histogram. Traditional radionuclide identification methods can be applied once the contribution gamma energies have been identified. As an added benefit: locating natural background gamma rays: 238 keV, 609 keV, 1460 keV, and 2614 keV in the deconvolved spectrum can be used to gain-stabilize the PVT detector.
由掺有荧光染料的聚乙烯烃甲苯1(PVT)制成的塑料闪烁体广泛用于国土安全、废金属检查和其他需要大面积、经济高效的伽马探测器的应用中。不幸的是,使用PVT进行伽马射线探测只能得到康普顿边缘事件,而康普顿边缘事件导致了宽连续光谱,没有可识别的特征。从低分辨率PVT光谱中获取信息的其他方法已经在出版物中描述过,但目前还没有适合常规使用的实用方法。我们开发了一种基于粒子群优化(PSO)的方法,该方法分析原始PVT光谱,并提供贡献(s)与入射单能γ能量(s)的直方图。这是通过将多个单能量计算的PVT伽马响应累加到一个“谱”中来完成的,直到获得与原始数据谱的“最佳拟合”。响应函数输入集采用MCNP5计算,覆盖合适的能量范围;我们使用一组255个响应函数,它们之间间隔为11 keV(这对应于我们的PVT检测器中使用的ADC增益)。该装置提供11 keV至2805 keV的入射单能伽马能量范围,适用于大多数应用。通常,我们发现在计算的直方图中只有一个或两个伽马响应函数对“峰值”有贡献。一旦确定了贡献能量,就可以应用传统的放射性核素鉴定方法。作为一个额外的好处:定位自然背景伽马射线:238 keV, 609 keV, 1460 keV和2614 keV在反卷积频谱可以用来获得稳定的PVT探测器。
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引用次数: 1
Assessment of the Non-Linear Response of DEPFET Sensors with Signal Compression 信号压缩下DEPFET传感器非线性响应的评估
Pub Date : 2020-10-31 DOI: 10.1109/NSS/MIC42677.2020.9508034
A. Castoldi, C. Guazzoni, S. Aschauer, L. Strüder, K. Hansen, S. Maffessanti, M. Porro
The implementation of a Depleted Field Effect Transistor (DEPFET) in each pixel of the DSSC (DEPFET Sensor with Signal Compression) X-ray camera for the European XFEL is intended to provide the appropriate signal compression at high injection levels and low noise figure. The aim of this work is the assessment of the non-linear DEPFET response. To this purpose the response of DSSC DEPFET pixels has been measured and analyzed up to 2 MeV equivalent deposited energy in the experimental conditions foreseen for the final DSSC camera. An appropriate fitting function has been introduced to predict the compression “kink” positions and to model the shape of the compression curve. The preliminary results of this study will be summarized.
在欧洲XFEL的DSSC(带信号压缩的DEPFET传感器)x射线相机的每个像素中实现耗尽场效应晶体管(DEPFET),旨在提供高注入水平和低噪声系数下适当的信号压缩。这项工作的目的是评估非线性DEPFET响应。为此,在最终DSSC相机的实验条件下,测量和分析了DSSC DEPFET像素的响应,最高可达2 MeV的等效沉积能量。引入合适的拟合函数来预测压缩“扭结”位置,并对压缩曲线的形状进行建模。本文将对本研究的初步结果进行总结。
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引用次数: 0
Time-of-Flight Spectroscopy of 252Cf Spontaneous Fission Neutrons: Influences of Detector Voltage, Pulse-Shape Discrimination and Shielding 252Cf自发裂变中子的飞行时间光谱:探测器电压、脉冲形状判别和屏蔽的影响
Pub Date : 2020-10-31 DOI: 10.1109/NSS/MIC42677.2020.9507768
Alex Grievson, C. J. Taylor, N. Roberts, M. Bunce, M. Joyce
Experimental measurements to explore the effect of detector voltage, pulse-shape discrimination (PSD) threshold and detector shielding on time-of-flight measurements of the 252Cf neutron spectrum made with organic scintillation detectors are described. It is found that detector voltage has a major effect, whilst changing the PSD threshold and shielding the detectors to optimize sensitivity to the desired γ-neutron correlation results in a small effect.
本文描述了探测器电压、脉冲形状判别阈值和探测器屏蔽对用有机闪烁探测器测量252Cf中子能谱飞行时间影响的实验测量。研究发现,探测器电压对γ-中子相关的灵敏度有主要影响,而改变PSD阈值和屏蔽探测器以优化所需的γ-中子相关灵敏度的影响较小。
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引用次数: 0
Neural Network-based Inter-crystal Scatter Event Positioning in a PET System Design Based on 3D Position Sensitive Detectors 基于三维位置敏感探测器的PET系统设计中基于神经网络的晶体间散射事件定位
Pub Date : 2020-10-31 DOI: 10.1109/NSS/MIC42677.2020.9507821
C. Wu, M. S. Lee, C. Levin
We demonstrate a simulation-based proof-of-concept for superior inter-crystal scatter (ICS) event positioning using a feed-forward neural network (NN) architecture compared to traditional winner-takes-all (WTA) and loser-takes-all (LTA) algorithms. Using a GATE Monte Carlo simulation of a 3D position-sensitive scintillation detector module comprising long crystals read out from the side using SiPMs with 3×3×3 mm3 effective detector voxels, we observe NN ICS event positioning accuracies of 0.753 to 0.680 when the number of interactions per annihilation photon ranges from 2 to 5: significantly more robust compared to 0.726 to 0.367 for LTA and 0.613 to 0.251 for WTA methods over the same range. We then scale the single-detector simulation into a 25 cm diameter PET brain imaging system and reconstruct contrast and resolution phantoms for image quality analysis. The NN model outperformed both WTA and LTA, with image normalized Mean Absolute Errors of 0.030 and 0.122 for contrast and resolution phantoms compared to 0.046, 0.178 and 0.034, 0.140 for WTA and LTA. The NN demonstrated 6.04 to 8.95% higher Contrast Recovery (from resolution phantom), 0.53 to 2.85% larger Contrast Noise Ratio (from contrast phantom), and 2.13 to 6.34% higher Modulation Transfer Function values (from resolution phantom) compared to LTA, which performed second-best. The upper bound for these NN relative improvements occurred with features near the spatial resolution limit of the simulated system (2 mm). Our results indicate the NN positioning approach we examined improves most image quality and quantitation figures of merit.
与传统的赢者通吃(WTA)和输者通吃(LTA)算法相比,我们使用前馈神经网络(NN)架构演示了基于仿真的优越晶间散射(ICS)事件定位的概念验证。利用GATE蒙特卡罗模拟了一个三维位置敏感闪烁探测器模块,该模块由使用具有3×3×3 mm3有效探测器体素的SiPMs从侧面读取的长晶体组成,我们观察到,当每个湮灭光子的相互作用数量范围为2到5时,NN ICS事件定位精度为0.753到0.680,与LTA方法的0.726到0.367和WTA方法的0.613到0.251相比,在相同范围内具有更强的鲁棒性。然后,我们将单探测器模拟扩展到直径为25厘米的PET脑成像系统中,并重建对比度和分辨率幻象,用于图像质量分析。NN模型的表现优于WTA和LTA,对比度和分辨率的图像归一化平均绝对误差分别为0.030和0.122,而WTA和LTA的图像归一化平均绝对误差分别为0.046、0.178和0.034、0.140。与表现第二好的LTA相比,该NN的对比度恢复(来自分辨率幻影)高出6.04至8.95%,对比度噪声比(来自对比度幻影)高出0.53至2.85%,调制传递函数值(来自分辨率幻影)高出2.13至6.34%。这些神经网络相对改进的上界发生在接近模拟系统空间分辨率极限(2mm)的特征上。我们的结果表明,我们研究的神经网络定位方法提高了大多数图像质量和量化指标。
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引用次数: 3
Interface for Exchanging Geometric Parameters in Geant4 Based Particle Therapy Simulation Framework 基于Geant4的粒子治疗仿真框架中几何参数交换的接口
Pub Date : 2020-10-31 DOI: 10.1109/NSS/MIC42677.2020.9507843
T. Aso, C. Omachi, T. Toshito, T. Sasaki
The particle therapy system simulation framework (PTSIM) is a Geant4 based Monte Carlo simulation software developed for radiation therapy. It has been continuously extending the functions to facilitate advanced researches in medical physics domain. Consequently, the PTSIM is used in many facilities for verification of treatment plans and quality assurances. In the PTSIM, various types of beam devices are provided as software components named “beam-modules”. The geometry is constructed using a class of the beam-module and the detail geometric parameters in the ASCII data format. This strategy contributed that allows the PTSIM users to easily find the beam-module from the categorized types of beam devices and to develop a rapid prototyping of treatment port in the simulation. However, radiation therapy facilities may introduce variants of existing beam-modules, that may require the implementation of a new class for the beam-module in the PTSIM. In order to respond to such requirements without any coding effort, the interface for the Geometry Description Markup Language (GDML) has been introduced in the PTSIM. The GDML is a specialized XML-based language for an application-independent persistent format. Therefore, it can describe a user-defined complex geometry and exchanging the geometry data file among different facilities. In addition, for the purpose of examining complex geometries, a new interface for the ParaView visualization software has been developed. The interface converts the geometry in the PTSIM to the structured points data in the VTK legacy format. This paper reports on the implementations and the usages of GDML and ParaView interfaces in the PTSIM.
粒子治疗系统模拟框架(PTSIM)是一个基于Geant4的蒙特卡罗模拟软件,开发用于放射治疗。它一直在不断扩展功能,以促进医学物理领域的先进研究。因此,PTSIM在许多设施中用于验证治疗计划和质量保证。在PTSIM中,各种类型的波束设备作为称为“波束模块”的软件组件提供。几何结构是使用一类波束模块和ASCII数据格式的详细几何参数来构建的。该策略使得PTSIM用户可以轻松地从光束设备的分类类型中找到光束模块,并在模拟中开发治疗端口的快速原型。然而,放射治疗设施可能会引入现有波束模块的变体,这可能需要在PTSIM中实现新的波束模块类。为了在没有任何编码工作的情况下响应这些需求,PTSIM中引入了几何描述标记语言(GDML)的接口。GDML是一种专门的基于xml的语言,用于独立于应用程序的持久格式。因此,它可以描述用户自定义的复杂几何,并在不同的工具之间交换几何数据文件。此外,为了检查复杂的几何形状,ParaView可视化软件开发了一个新的界面。该接口将PTSIM中的几何图形转换为VTK遗留格式的结构化点数据。本文介绍了PTSIM中GDML和ParaView接口的实现和使用方法。
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引用次数: 0
The Influence of Laser Surface Treatment on Properties of CdTe X- and γ-ray Detectors 激光表面处理对CdTe X射线和γ射线探测器性能的影响
Pub Date : 2020-10-31 DOI: 10.1109/NSS/MIC42677.2020.9507823
O. Maslyanchuk, V. Strebezhev, P. Fochuk, I. Fodchuk, M. Solovan, M. Sorokatyi, I. Boledzyuk, R. James
In this paper, the transformations of the morphology and surface structure of CdTe crystals under the action of pulsed laser radiation and the properties of laser-optimized Schottky diode X/γ-ray detectors developed by Ni and NiO deposition onto commercially available (111) oriented CdTe:Cl wafers has been investigated. Using scanning electron and atomic force microscopy, it was shown that, depending on the energy density and laser pulse duration, the morphology, phase composition and distribution of the system of defects and inclusions in the surface areas of CdTe crystals can be optimized. The analysis of the effect of laser treatment on the electrical and spectrometric properties CdTe X/γ-ray detectors under study was also carried out.
本文研究了脉冲激光辐射作用下CdTe晶体形貌和表面结构的变化,以及利用Ni和NiO沉积在市产(111)取向CdTe:Cl晶片上开发的激光优化肖特基二极管X/γ射线探测器的性能。利用扫描电子显微镜和原子力显微镜研究发现,不同能量密度和激光脉冲时间可以优化CdTe晶体表面缺陷和夹杂体系的形貌、相组成和分布。分析了激光处理对所研究的CdTe X/γ射线探测器的电学和光谱特性的影响。
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引用次数: 0
Multiple PET Reconstruction Assisted Non-local Mean Denoising of PET Images 多重PET重构辅助PET图像非局部均值去噪
Pub Date : 2020-10-31 DOI: 10.1109/NSS/MIC42677.2020.9507772
Hossein ARABI, H. Zaidi
Non-local mean (NLM) denoising is commonly used for noise suppression in natural as well as medical imaging. Basically, the NLM filter takes advantage of the redundant information present in the image in the form of repeated structures/patterns to identify the underlying signals. In medical imaging (particularly PET and SPECT imaging), different representations of the image data under study (target or original image) could be reconstructed via applying different reconstruction settings. These representative (auxiliary) images bear very similar patterns/structures to the original/target image with different signal-to-noise ratios (SNR) which are ideal for use in the NLM denoising approach. This study proposed the multiple-reconstruction NLM filtering approach (referred to as MR-NLM) for noise reduction in PET imaging, wherein the redundant information present in auxiliary PET images are employed to conduct the NLM denoising process. The MR-NLM method relies on 12 additional PET image reconstructions (apart from the target PET image) using the same iterative algorithm with different iterations and subset numbers. Thereafter, for each target voxel, patches of voxels are extracted at the same location from all auxiliary PET images to be fed into the NLM smoothing process. To evaluate the performance of the MR-NLM algorithm, post-reconstruction denoising approaches including the conventional NLM, bilateral, and Gaussian filters were implemented and compared using 25 18F-FDG clinical whole-body (WB) PET/CT studies. The clinical studies demonstrated superior performance of the MR-NLM approach which established a promising compromise between noise suppression and preservation of the underlying signal/structures in PET images leading to higher SNR compared to the conventional NLM approach (34.9±5.7 versus 32.4±5.5). Though MR-NLM exhibited promising performance, this method suffers from long processing time due to the requirement of multiple reconstructions of raw PET data.
非局部平均(NLM)去噪是自然成像和医学成像中常用的噪声抑制方法。基本上,NLM滤波器利用图像中以重复结构/模式的形式存在的冗余信息来识别底层信号。在医学成像(特别是PET和SPECT成像)中,可以通过应用不同的重建设置来重建所研究的图像数据(目标图像或原始图像)的不同表示。这些代表性(辅助)图像具有与原始/目标图像非常相似的模式/结构,具有不同的信噪比(SNR),非常适合用于NLM去噪方法。本研究提出了PET成像降噪的多重重构NLM滤波方法(简称MR-NLM),利用辅助PET图像中存在的冗余信息进行NLM去噪处理。MR-NLM方法依赖于12个额外的PET图像重建(除了目标PET图像),使用相同的迭代算法,不同的迭代和子集数。然后,对于每个目标体素,从所有辅助PET图像中提取相同位置的体素块,并将其送入NLM平滑处理。为了评估MR-NLM算法的性能,实施了包括传统NLM、双侧和高斯滤波器在内的重建后去噪方法,并与25个18F-FDG临床全身(WB) PET/CT研究进行了比较。临床研究证明了MR-NLM入路的优越性能,它在PET图像的噪声抑制和底层信号/结构的保存之间建立了有希望的折衷,与传统NLM入路相比,信噪比更高(34.9±5.7比32.4±5.5)。尽管MR-NLM表现出了良好的性能,但由于需要对原始PET数据进行多次重建,该方法的处理时间较长。
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引用次数: 0
Investigation of Analog and Digital Signal Processing Chains for a Prototype TOF-PET System with 100 ps Coincidence Time Resolution 具有100ps符合时间分辨率的TOF-PET原型系统模拟和数字信号处理链的研究
Pub Date : 2020-10-31 DOI: 10.1109/NSS/MIC42677.2020.9508016
S. Pourashraf, A. Gonzalez-Montoro, M. S. Lee, J. Cates, Jun Yeon Won, Zhixiang Zhao, Jae Sung Lee, C. Levin
To achieve < 100 ps Coincidence Time Resolution (CTR) and a > 2 - fold improvement in reconstructed image Signal to Noise Ratio (SNR) compared to state-of-the-art TOF-PET scanners, we have evaluated CTR performance of three different mixed-signal front-end electronic configurations. The proposed TOF-PET detector elements are based on two 3×3×10 mm3 “LGSO” crystal segments for a 20 mm effective length and side-coupled to arrays of 3×3 mm2 SiPMs. The front-end readouts were based on: a) high speed RF amplifiers; b) NINO ASIC as discriminator, and; c) combination of both RF+NINO. Coincidence data were experimentally acquired using the 10 mm length crystals, a low jitter FPGA-based TDC, several SiPM bias voltages, and NINO thresholds, achieving CTR value of 103.3 ± 1.5 ps FWHM using configuration (c). This value is much improved compared to the results achieved using configurations (a) and (b).
与最先进的TOF-PET扫描仪相比,为了实现< 100 ps的符合时间分辨率(CTR)和> 2倍的重建图像信噪比(SNR)改善,我们评估了三种不同的混合信号前端电子配置的CTR性能。提出的TOF-PET检测器元件基于两个有效长度为20 mm的3×3×10 mm3“LGSO”晶体段,并侧耦合到3×3 mm2 sipm阵列。前端读出基于:a)高速射频放大器;b) NINO ASIC作为鉴别器;c) RF+NINO的组合。采用10mm长度的晶体、低抖动的fpga TDC、几个SiPM偏置电压和NINO阈值,实验获得了符合数据,使用配置(c)获得了103.3±1.5 ps FWHM的CTR值。与使用配置(a)和(b)获得的结果相比,该值大大提高。
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引用次数: 3
期刊
2020 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)
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