银屑病角质形成细胞

Z. Bata-Csorgo, M. Széll
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引用次数: 20

摘要

银屑病是一种炎症性皮肤病,表皮发生特征性变化,类似于角化细胞过度过度增殖导致的未抑制的伤口愈合。角质形成细胞增生还伴有细胞的异常分化。目前尚不清楚角质形成细胞对疾病病理的影响程度。然而,在这篇文章中,作者试图总结有关角质细胞异常行为在银屑病皮损病理机制中的重要性的数据。
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The psoriatic keratinocytes
Psoriasis is an inflammatory skin disease with characteristic changes in the epidermis that resembles unsuppressed wound healing due to excessive hyperproliferation of keratinocytes. The keratinocyte hyperproliferation is also accompanied by abnormal differentiation of cells. It is not clear how much keratinocytes contribute to disease pathology. In this article, the authors, however, attempt to summarize data that argue for the importance of abnormal keratinocyte behavior in the pathomechanism of psoriatic skin lesions.
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