三级医院ICU患者耐碳青霉烯鲍曼不动杆菌:一项回顾性研究,强调其人口统计学和临床概况,对ICU住院时间和死亡率的影响

Supriya Dey, L. Rani
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摘要

在世界上许多医院被认为是院内呼吸道感染和菌血症的主要原因。然而,对于是否独立于其他风险因素的影响,殖民化和/或感染会增加发病率和死亡率,仍然存在争议。本研究的目的是对ICU患者进行分离,检测ICU感染患者对碳青霉烯类药物的耐药情况,并确定螃蟹分离株感染的具体危险因素和结局。回顾性研究于2021年6月至2022年5月在班加罗尔的Vydehi医学科学研究所和研究中心的重症监护室进行。所有患者中碳青霉烯类耐药以60岁以上患者多见,男性多于女性,患者多采用通气和脓毒症,死亡率随ICU住院时间的延长而增高。是ICU患者中高度流行的微生物,而其对常用抗生素产生耐药性的潜力代表了它对医疗保健行业的严重威胁。因此,这表明需要在卫生保健机构中对其进行定期监测。在我们的ICU中,螃蟹引起的VAP和过度使用血管内器械是螃蟹菌血症最重要的危险因素。早期实施适当的抗菌药物治疗,特别是对患有碳青霉烯耐药感染并伴有两种或两种以上合并症的重症ICU患者,可能对生存至关重要。
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Carbapenem resistant Acinetobacter baumannii in ICU patients in a tertiary care hospital: A retrospective study highlighting their demographic and clinical profile, impact on ICU stay and mortality
: was considered as a leading cause of nosocomial respiratory infection and bacteremia in many hospitals all over the world. However, there was a still a debates whether colonization and/or infection with , increases morbidity and mortality independently of the effect of other risk factors.Aim of the study was to isolate among ICU patients, to detect carbapenem resistant among ICU patients with infections and to determine specific risk factors and outcome of the infections due to CRAB isolates. : A retrospective study was carried out at Vydehi Institute of Medical Sciences and RC in Bangalore, in the ICU department from June 2021 to May 2022.Among all the patients carbapenem resistance was detected more in patients above 60 years of age, males were predominant than females, most of the patients were on ventilation and in sepsis and mortality rate was high with the increased duration of ICU stays. is a highly prevalent microorganism among ICU patients, while its potential to acquire resistance toward commonly used antibiotics represents it as a grave threat to the health care industry. Therefore, signifying the need for its regular monitoring in the health care setups. VAP due to CRAB and excess use of intravascular devices are the most important risk factors for CRAB bacteremia in our ICU. Early implementation of appropriate antimicrobial therapy, particularly in critically ill ICU patients with Carbapenem resistant infections, with two or more co morbidities, can be crucial for survival.
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