脑瘫痉挛性髋内收患儿肌肉纤维分类及大收肌超微结构研究

Yani Tang
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引用次数: 0

摘要

目的探讨脑瘫痉挛性海马收缩时大收肌的超微结构损伤及肌纤维类型。方法选取16例手术治疗的脑瘫痉挛性髋内收患儿大收肌标本,用肌球蛋白三磷酸腺苷酶进行组织化学检查,对其肌纤维分类和超结构进行研究。结果ⅰ型纤维(慢抽动纤维)所占比例(70.92%)明显高于对照组(57.93%),且常聚集形成类型分组。所有试件均出现超结构损伤。结论这些异常是引起肌肉痉挛性收缩的因素之一,手术治疗无远期效果。导致纤维类型转变的原因有待进一步研究。
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Classication of muscles fibers and ultra-structural study on adductor magnus muscles in children with spastic hip adduction from cerebral palsy
Objective To study ultrastructural damages and classification of types in muscles fibers in the adductor magnus muscles with spastic hipadduction of cerebral palsy. Methods Specimens of the adductor magnus muscles were ta ken from 16 surgically treated children with spastic hip adduction of cerebral palsy,histochemistry examined with muscles globulin ATP ase olye for the classification of muscles fibers and ultra structure also studied. Results The type I fibers,slow twitch fibers,were found to occupy a significantly higher ratio(70.92%)than controls( 57.93% ),and were often gathered to form type grouping.Ultra structural damages were found in all of the specimens. Conclusion It is suggested that these abnormalities are one of the factors a which cause spastic contraction of muscles without long term effects by surgical treatment.The reason which leads to transformation of the fiber types needs further investigation.
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