Pub Date : 2014-07-20DOI: 10.3760/CMA.J.ISSN.2095-428X.2014.14.012
H. Tong, Huiying Xu, Chunlan Zhou, Peng Zeng
Objective To study the effect of Sandra Fucile oral stimulation on oral feeding readiness and ability of preterm infants. Methods Sixty-five premature infants were selected in the study.All of the premature infants were recruited randomly in convenience between Jul.and Dec.2012.For a randomized control principle, SPSS 13.0 was performed to achieve complete random design.Objects were divided into control group(receiving routine nursing) and intervention group(on the basis of routine nursing, receiving 15 minutes oral stimulation, 1 time/day, for 10 days). Chinese version of Preterm Infant Oral Feeding Readiness Assessment scale(PIOFRA scale-CV) was used when intervention began, and 7 days, 10 days, 14 days after the start of the intervention. Results PIOFRA-CV scale score was statistically different at different time in both groups(F=169.062, P 0.05). Conclusions Saudra Fucile oral stimulation method can significantly promote the development of premature oral feeding ability on the 10 day after the intervention, and will not increase vomiting, gastroesophageal reflux, and infection.It is suitable for clinical application. Key words: Chinese version of Preterm Infant Oral Feeding Readiness Assessment Scale; Oral stimulation; Preterm infant
{"title":"Effect of oral stimulation on oral feeding ability of preterm infants","authors":"H. Tong, Huiying Xu, Chunlan Zhou, Peng Zeng","doi":"10.3760/CMA.J.ISSN.2095-428X.2014.14.012","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.2095-428X.2014.14.012","url":null,"abstract":"Objective \u0000To study the effect of Sandra Fucile oral stimulation on oral feeding readiness and ability of preterm infants. \u0000 \u0000 \u0000Methods \u0000Sixty-five premature infants were selected in the study.All of the premature infants were recruited randomly in convenience between Jul.and Dec.2012.For a randomized control principle, SPSS 13.0 was performed to achieve complete random design.Objects were divided into control group(receiving routine nursing) and intervention group(on the basis of routine nursing, receiving 15 minutes oral stimulation, 1 time/day, for 10 days). Chinese version of Preterm Infant Oral Feeding Readiness Assessment scale(PIOFRA scale-CV) was used when intervention began, and 7 days, 10 days, 14 days after the start of the intervention. \u0000 \u0000 \u0000Results \u0000PIOFRA-CV scale score was statistically different at different time in both groups(F=169.062, P 0.05). \u0000 \u0000 \u0000Conclusions \u0000Saudra Fucile oral stimulation method can significantly promote the development of premature oral feeding ability on the 10 day after the intervention, and will not increase vomiting, gastroesophageal reflux, and infection.It is suitable for clinical application. \u0000 \u0000 \u0000Key words: \u0000Chinese version of Preterm Infant Oral Feeding Readiness Assessment Scale; Oral stimulation; Preterm infant","PeriodicalId":14986,"journal":{"name":"Journal of Applied Clinical Pediatrics","volume":"98 1","pages":"1087-1091"},"PeriodicalIF":0.0,"publicationDate":"2014-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81171189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2003-02-05DOI: 10.3969/J.ISSN.1003-515X.2003.02.008
Ke-lun Wei
Objective To study the effect of tumor necrosis factor alpha(TNF α)on inflammatory reaction in fetal rat kidney after acute ischemia.Methods By clamping one side of vessels supplying blood to uterus of Wistar rats of 21 gestational days, we made the models of intrauterine acute ischemia in different degrees and the reperfusion models in fetal rats. TNF α and myeloperoxidase (MPO) in fetal kidney tissue were detected by ELISA and biochemically respectively, and the renal histopathological changes were also observed.Results The activity of TNT α increased gradually with the extension of ischemia, especially after 35～45 minutes (P 0.05) .It rose progressively during reperfusion and was at its highest after 8 hours (P0.01) .It reached the level of the sham operation group after 30 hours reperfusion .The activity of MPO changed as that of TNF α . The activity of MPO reached the peak in 15 hours of reperfusion (P0.01) . Histological changes were most prominent after 15 hours reperfusion, including vascular congestion, tubular vacuolar degeneration or necrosis and neutrophil accumulation basement membrane breakdown, especially in proximal end of tubules.Conclusions There is inflammatory reaction in renal injury induced by intrauterine ischemia and reperfusion, TNF α may be one of important mediator and MPO can reflect the degree of inflammatory reaction.
{"title":"Effect of tumor necrosis factor-alpha on inflammatory reaction in fetal rat kidney after acute ischemia","authors":"Ke-lun Wei","doi":"10.3969/J.ISSN.1003-515X.2003.02.008","DOIUrl":"https://doi.org/10.3969/J.ISSN.1003-515X.2003.02.008","url":null,"abstract":"Objective To study the effect of tumor necrosis factor alpha(TNF α)on inflammatory reaction in fetal rat kidney after acute ischemia.Methods By clamping one side of vessels supplying blood to uterus of Wistar rats of 21 gestational days, we made the models of intrauterine acute ischemia in different degrees and the reperfusion models in fetal rats. TNF α and myeloperoxidase (MPO) in fetal kidney tissue were detected by ELISA and biochemically respectively, and the renal histopathological changes were also observed.Results The activity of TNT α increased gradually with the extension of ischemia, especially after 35～45 minutes (P 0.05) .It rose progressively during reperfusion and was at its highest after 8 hours (P0.01) .It reached the level of the sham operation group after 30 hours reperfusion .The activity of MPO changed as that of TNF α . The activity of MPO reached the peak in 15 hours of reperfusion (P0.01) . Histological changes were most prominent after 15 hours reperfusion, including vascular congestion, tubular vacuolar degeneration or necrosis and neutrophil accumulation basement membrane breakdown, especially in proximal end of tubules.Conclusions There is inflammatory reaction in renal injury induced by intrauterine ischemia and reperfusion, TNF α may be one of important mediator and MPO can reflect the degree of inflammatory reaction.","PeriodicalId":14986,"journal":{"name":"Journal of Applied Clinical Pediatrics","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2003-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89169909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2002-06-05DOI: 10.3969/J.ISSN.1003-515X.2002.03.002
Sheng-fu Li
Objectives To observe the role of brain derived neurotrophic factor (BDNF) in hypoxia induced cortical neurons to provide new laboratory evidence for further application of BDNF in clinical practice. Methods The survival rates of cultural fetal cortical neurons were tested and the influence of adding BDNF to the culture medium on survival rates was observed though trypanblue dye; the activity of the cortical neurons was detected using MTT. Results We observed that BDNF could protect the cortical neurons from hypoxia induced neurotoxicity by preincubating the neurons before 24 hours with BDNF and adding BDNF to the cultured neurons just before exposing them to hypoxic cultural environment.The survival rate of the cortical neurons was significantly reduced after exposing to hypoxia environment, while pre incubation of the cortical neurons with BDNF before 24hr and just before exposing to hypoxia showed much higher survival rates than that of the control group in terms of preventing hypoxia neurotoxicity. So this protection was time dependent.Conclusions In vitro, BDNF plays an important role in preventing cortical neurons from hypoxia induced neurotoxicity.
{"title":"Role of brain-derived neurotrophic factor in hypoxia-induced fetal cortical neurons","authors":"Sheng-fu Li","doi":"10.3969/J.ISSN.1003-515X.2002.03.002","DOIUrl":"https://doi.org/10.3969/J.ISSN.1003-515X.2002.03.002","url":null,"abstract":"Objectives To observe the role of brain derived neurotrophic factor (BDNF) in hypoxia induced cortical neurons to provide new laboratory evidence for further application of BDNF in clinical practice. Methods The survival rates of cultural fetal cortical neurons were tested and the influence of adding BDNF to the culture medium on survival rates was observed though trypanblue dye; the activity of the cortical neurons was detected using MTT. Results We observed that BDNF could protect the cortical neurons from hypoxia induced neurotoxicity by preincubating the neurons before 24 hours with BDNF and adding BDNF to the cultured neurons just before exposing them to hypoxic cultural environment.The survival rate of the cortical neurons was significantly reduced after exposing to hypoxia environment, while pre incubation of the cortical neurons with BDNF before 24hr and just before exposing to hypoxia showed much higher survival rates than that of the control group in terms of preventing hypoxia neurotoxicity. So this protection was time dependent.Conclusions In vitro, BDNF plays an important role in preventing cortical neurons from hypoxia induced neurotoxicity.","PeriodicalId":14986,"journal":{"name":"Journal of Applied Clinical Pediatrics","volume":"67 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2002-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86046653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Premature atherogensis in the healed arteritis induced during the weaning period","authors":"Liu Ya-li, H. Xiao-hua","doi":"10.3969/J.ISSN.1003-515X.2000.01.002","DOIUrl":"https://doi.org/10.3969/J.ISSN.1003-515X.2000.01.002","url":null,"abstract":"目的探讨川崎病远期冠状动脉硬化发生的危险性.方法实验分为两组:A组用马血清诱发兔的动脉炎,3mo后加用含5%胆固醇饲料喂养;B组未诱发动脉炎,饲料喂养同A组,5mo时两组取心脏做HE和马森染色,观察冠状动脉的病理组织学变化,IBAS画像解析装置测算.结果A组冠状动脉主干部内膜的肥厚、纤维性硬化以及心肌内冠状动脉的硬化程度均比B组明显(P＜0.05).结论动脉炎后冠状动脉内膜的隐匿性病变使患病血管比正常血管更易诱发动脉硬化.","PeriodicalId":14986,"journal":{"name":"Journal of Applied Clinical Pediatrics","volume":"42 1","pages":"4-5"},"PeriodicalIF":0.0,"publicationDate":"2000-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73555607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2000-02-05DOI: 10.3969/J.ISSN.1003-515X.2000.01.004
Yani Tang
Objective To study ultrastructural damages and classification of types in muscles fibers in the adductor magnus muscles with spastic hipadduction of cerebral palsy. Methods Specimens of the adductor magnus muscles were ta ken from 16 surgically treated children with spastic hip adduction of cerebral palsy,histochemistry examined with muscles globulin ATP ase olye for the classification of muscles fibers and ultra structure also studied. Results The type I fibers,slow twitch fibers,were found to occupy a significantly higher ratio(70.92%)than controls( 57.93% ),and were often gathered to form type grouping.Ultra structural damages were found in all of the specimens. Conclusion It is suggested that these abnormalities are one of the factors a which cause spastic contraction of muscles without long term effects by surgical treatment.The reason which leads to transformation of the fiber types needs further investigation.
{"title":"Classication of muscles fibers and ultra-structural study on adductor magnus muscles in children with spastic hip adduction from cerebral palsy","authors":"Yani Tang","doi":"10.3969/J.ISSN.1003-515X.2000.01.004","DOIUrl":"https://doi.org/10.3969/J.ISSN.1003-515X.2000.01.004","url":null,"abstract":"Objective To study ultrastructural damages and classification of types in muscles fibers in the adductor magnus muscles with spastic hipadduction of cerebral palsy. Methods Specimens of the adductor magnus muscles were ta ken from 16 surgically treated children with spastic hip adduction of cerebral palsy,histochemistry examined with muscles globulin ATP ase olye for the classification of muscles fibers and ultra structure also studied. Results The type I fibers,slow twitch fibers,were found to occupy a significantly higher ratio(70.92%)than controls( 57.93% ),and were often gathered to form type grouping.Ultra structural damages were found in all of the specimens. Conclusion It is suggested that these abnormalities are one of the factors a which cause spastic contraction of muscles without long term effects by surgical treatment.The reason which leads to transformation of the fiber types needs further investigation.","PeriodicalId":14986,"journal":{"name":"Journal of Applied Clinical Pediatrics","volume":"378 1","pages":"8-9"},"PeriodicalIF":0.0,"publicationDate":"2000-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80616820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Diagnosis and treatment of cerebral malaria in children","authors":"Xiao Li-qin, Jin Zhong-He, Xiang Cheng-fa","doi":"10.3969/J.ISSN.1003-515X.2000.01.007","DOIUrl":"https://doi.org/10.3969/J.ISSN.1003-515X.2000.01.007","url":null,"abstract":"目的了解儿童脑型疟临床特征和降低其病死率.方法对1996～1997年住院128例儿童脑型疟的临床特征、诊断治疗、病死原因进行分析.结果1～5a儿童发生率66%,痊愈113例,后遗症4例,死亡11例,死亡率8.6%.临床特征有发热、咳嗽、吐泻、惊厥、意识障碍等.血片见疟原虫可确诊,首次阴性应反复多次检查.惊厥、意识障碍者应排除其他疾患.结论及时正确诊断,尽早抗疟治疗,对抗药性及有并发症等治疗是降低儿童脑型疟病死率的关键.","PeriodicalId":14986,"journal":{"name":"Journal of Applied Clinical Pediatrics","volume":"1 1","pages":"14-15"},"PeriodicalIF":0.0,"publicationDate":"2000-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83103114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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