子痫前期及子痫综合征胎儿结局的研究

F. Rahman, Mushtaq Ahmad, Mousumi Ahmed, N. Afroze, Md Zubaidur Rahman
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摘要

背景:子痫前期及子痫综合征是女性最常见的医学疾病之一。由于这种疾病,新生儿的结局与正常妊娠不同。它包括死产、低出生体重、窒息和早产。目的:本研究的目的是确定不同组子痫前期和子痫综合征的胎儿结局。材料和方法:本横断面观察性研究于2019年7月至2021年6月在达卡(BIRDEM)总医院病理科进行。本研究纳入了138例临床诊断为子痫前期和子痫综合征的患者,分别来自BIRDEM和DMCH的妇产科。138例中,轻度子痫前期(轻度PE) 42例,重度子痫前期(重度PE) 62例,子痫33例。观察相关数据和妊娠结局(新生儿出生体重、成熟度、Apgar评分和死胎),并记录在预先设计的数据收集表中,进行统计分析。在研究的每一步都要确保道德规范。结果:138例患儿中,轻度子痫前期组平均出生体重为(2.12±0.57)kg,子痫前期组平均出生体重为(1.52±0.47)kg。重度PE患儿Apgar评分低(评分小于7)占77.8%,其次为子痫组(84.8%)。子痫组超过半数的新生儿结局为死胎(54.4%)。三组妊娠结局(新生儿体重、成熟度、死胎等)差异有统计学意义。结论:多数胎儿并发症与子痫前期及子痫综合征的严重程度和持续时间有关。《医药学刊》第14卷第1期,2023年4月:39-42
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Study of Fetal Outcome in Preeclampsia and Eclampsia Syndrome
Background: Preeclampsia and eclampsia syndrome is one of the commonest medical disorders of females. The neonatal outcome is different from the normal pregnancy due to this disorder. It includes- stillbirth, low birth weight, asphyxia, and prematurity.Objective: The objective of the study was to determine the fetal outcomes in different groups of preeclampsia and eclampsiasyndrome.Materials and Methods: This cross-sectional observational study was conducted in the Department of Pathology, (BIRDEM) General Hospital, Dhaka, from July 2019 to June 2021. The study comprised 138 clinically diagnosed preeclampsia and eclampsia syndrome cases from the Department of Gynecology & Obstetric of BIRDEM and DMCH. Out of 138 cases, there were 42 cases of mild preeclampsia (mild PE), 62 were of severe preeclampsia (severe PE), and 33 were eclampsia. Relevant data and pregnancy outcome (neonatal birth weight, maturity, Apgar score, and stillbirth), were observed and recorded in a predesigned data collection sheet and statistical analyses were carried out. Ethical practice was ensured in every step of the study.Results: Among 138 cases, the mean birth weight was (2.12±0.57) kg, which was observed in the mild preeclamptic group, and the mean birth weight was (1.52±0.47) kg found in the eclamptic group. A low Apgar score (score˂7) was mainly observed in the severe PE (77.8%) followed by (84.8%) in eclampsia group. More than half of the cases were revealed stillbirth (54.4%) as the neonatal outcome in eclampsia group. A statistically significant difference was found among three groups regarding pregnancy outcome (neonatal birth weight, maturity, stillbirth, etc.).Conclusion: Majority of the fetal complications were related to the severity and duration of the preeclampsia and eclampsia syndrome. KYAMC Journal Vol. 14, No. 01, April 2023: 39-42
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