菌根提取物是表皮葡萄球菌和丙戊酸阿坚菌的抗菌提取物

S. Nurjanah, Akhmad Rokiban, Erdy Irawan
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引用次数: 4

摘要

圆形夏柏的块茎被用于传统医学。已知含有次生代谢物的化合物,如生物碱、辛烷醇、蒎烯、siperon、roroal、siperenon、siperol、单宁、黄酮类化合物,科学上认为它具有抗菌活性。根据经验,这种植物被用作抗菌,抗肿瘤,抗癌和抗过敏。本研究旨在探讨香附提取物对表皮葡萄球菌和痤疮丙酸杆菌的抑菌作用。本研究采用70%乙醇浸渍法提取圆参。采用圆盘空白法测定提取物对表皮葡萄球菌和痤疮葡萄球菌的抑制作用。结果表明,浓度为20%、40%、60%、80%和100%的提取物对表皮葡萄球菌的抑制区平均直径分别为8.03 mm、11.43 mm、15.04 mm、15.83 mm和19.98 mm,对痤疮葡萄球菌的抑制区平均直径分别为11.59 mm、13.35 mm、17.17 mm、20.44 mm和30.08 mm,水合菌为阴性对照,红霉素为阳性对照。继续测定最低抑菌浓度(MIC)。表皮葡萄球菌的MIC为15%,痤疮葡萄球菌的MIC为11%。结果表明,该提取物对表皮葡萄球菌具有抑菌作用,对痤疮葡萄球菌具有抑菌作用。
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Ekstrak Umbi Rumput Teki (Cyperus Rotundus) Sebagai Antibakteri Terhadap Staphylococcus Epidermidis Dan Propionibacterium Acnes
The tuber of cyperus rotundus are used to tradisional medicine. C. rotundus known to contain compounds of secondary metabolites such as alkoloids, sineol, pinene, siperon, rotunal, siperenon, siperol, tannins, flavonoids and scientifically it has been believed to have antimicrobial activity. Empirically this plant are used as an antibacterial, antitumor, anticancer, and antiallergic. The purpose of this study were determining the inhibition of extract of Cyperus rotundus against tubers of Staphylococcus epidermidis and Propionibacterium acnes. In this study C. rotundus extracted by maceration using 70% ethanol. The extracts tested against S. epidermidis and P. acnes using disc blank method. The results obtained from the mean diameter of the inhibition zones of exstract at concentrations of 20%, 40%, 60%, 80%, and 100% on S. Epidermidis 8.03 mm, 11.43 mm, 15.04 mm, 15.83 mm and 19.98 mm respectively and P. acnes 11.59 mm, 13.35 mm, 17.17 mm, 20.44 mm, and 30.08 mm respectively Aquades used as negative control and erythromycin used as positive control. Testing were continued by determining the Minimum Inhibitory Concentration (MIC). The result of MIC for S. epidermidis was 15% and P. acnes was 11%. The analysis showed that the antibacterial activity of the tubers extract is bacteriostatic for S. epdermidis and bacterisid for P. acnes.
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