社会人口学特征与口腔癌的晚期临床阶段有关

Larissa Suelen da Silva Lins, N. Bezerra, A. R. Freire, L. F. D. de Almeida, E. D. de Lucena, Y. Cavalcanti
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Analyses on frequency distribution and multivariate binary logistic regression model were performed (α<0.05). Results Compared to individuals with no schooling, those who attended elementary to high school (OR=2.461) and college education (OR = 3.050) had a higher prevalence of advanced cases of oral cancer. Individuals without a partner (OR = 14,209) demonstrated a higher prevalence compared to married individuals. Subjects aged 20-44 years (OR = 4.081) and 45-64 years (OR = 14.875) had a higher prevalence compared to those aged 15-19 years. The variables gender, family history of cancer and origin of referral integrated the binary model of logistic regression, but did not present statistical significance. Conclusions Socioeconomic factors may be related to the advanced clinical stage of oral cancer. 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引用次数: 12

摘要

背景社会因素可能与口腔癌临床分期的发生和进展有关。目的:探讨社会人口学特征对口腔癌临床晚期患病率的影响。材料和方法从癌症登记信息系统中获得2000年至2012年期间来自巴西所有州的51,116例口腔癌病例的信息。将口腔癌的临床分期(因变量)分为初期(I期和II期)和晚期(III期和IV期)。分析口腔癌的临床分期与以下自变量的关系:性别、年龄、学历、婚姻状况、癌症家族史、转诊来源。频率分布及多元二元logistic回归模型分析(α<0.05)。结果与未接受过学校教育的人群相比,小学至高中学历(OR=2.461)和大学学历(OR= 3.050)的晚期口腔癌患病率较高。没有伴侣的个体(OR = 14,209)比已婚个体表现出更高的患病率。20-44岁(OR = 4.081)和45-64岁(OR = 14.875)的患病率高于15-19岁。性别、癌症家族史、转诊来源等变量整合logistic回归二元模型,但无统计学意义。结论社会经济因素可能与口腔癌临床进展有关。关键词:口腔肿瘤,肿瘤分期,健康的社会决定因素
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Socio-demographic characteristics are related to the advanced clinical stage of oral cancer
Background Social determinants may be associated with the onset and progression of the clinical stage of oral cancer. Aim: To evaluate the impact of socio-demographic characteristics on the prevalence of advanced clinical stage of oral cancer. Material and Methods Information about 51,116 cases of oral cancer, from all Brazilian states, between 2000 and 2012, was obtained from the Cancer Registry Information System. The clinical stage of oral cancer (dependent variable) was classified as initial (stages I and II) or advanced (stages III and IV). The relationship between the clinical stage of oral cancer and the following independent variables was analyzed: sex, age, schooling, marital status, family history of cancer, and origin of referral. Analyses on frequency distribution and multivariate binary logistic regression model were performed (α<0.05). Results Compared to individuals with no schooling, those who attended elementary to high school (OR=2.461) and college education (OR = 3.050) had a higher prevalence of advanced cases of oral cancer. Individuals without a partner (OR = 14,209) demonstrated a higher prevalence compared to married individuals. Subjects aged 20-44 years (OR = 4.081) and 45-64 years (OR = 14.875) had a higher prevalence compared to those aged 15-19 years. The variables gender, family history of cancer and origin of referral integrated the binary model of logistic regression, but did not present statistical significance. Conclusions Socioeconomic factors may be related to the advanced clinical stage of oral cancer. Key words:Mouth Neoplasms, Neoplasm Staging, Social Determinants of Health.
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