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Endoscopic findings in periapical surgery. A cross-sectional study of 206 roots 根尖周围手术的内窥镜表现。206根的横断面研究
Pub Date : 2022-06-05 DOI: 10.4317/medoral.25311
Pablo Glera-Suarez, Antonio Pallarés-Serrano, David Soto-Peñaloza, Beatriz Tarazona-Álvarez, M. Peñarrocha-Diago, D. Peñarrocha-Oltra
Background A study is made of the findings of high-magnification rigid endoscopy at the root end surface following apicoectomy of teeth subjected to periapical surgery. Material and Methods A cross-sectional study was made of patients subjected to periapical surgery at the Unit of Oral Surgery and Implantology (University of Valencia, Valencia, Spain) between 2011 and 2019. Following apicoectomy, the root end surfaces were inspected, with the evaluation of untreated canals, isthmuses, craze lines, crack lines, opaque dentin and gaps. Likewise, an analysis was made of the association between patient age and the tooth type and restoration and the presence of craze lines, cracks, opaque dentin and gaps. Results The final sample consisted of 168 patients subjected to periapical surgery, with 177 operated teeth and 206 roots. Untreated canals were observed in 14 roots (6.8%). Isthmuses were identified in 74 roots (35.9%), particularly in the mesial root of the lower first molar (94.1%). In turn, craze lines were identified in 8.3% of the roots, cracks in 3.9%, and gaps in 53.4%. The prevalence of opaque dentin was 78.3%, with a greater presence in posterior teeth (90.3% in premolars and 86.2% in molars) than in anterior teeth (50.6%) (p<0.001). Patient age and tooth restoration showed no correlation to the studied parameters. Conclusions Craze lines and crack lines were observed in less than 10% of the roots, though opaque dentin was identified in 73% of the roots, particularly in posterior teeth, and gaps were found in over half of the canals. Key words:Endoscope, cracks, gaps, opaque dentin, periapical surgery.
研究了在根尖切除后行根尖周手术的高倍率刚性内窥镜在根尖表面的观察结果。材料和方法对2011年至2019年在西班牙瓦伦西亚大学口腔外科和种植科(University of Valencia, Valencia, Spain)接受根尖周围手术的患者进行了横断面研究。根尖切除术后,检查根端面,评估未处理的根管、峡部、开裂线、裂纹线、不透明牙本质和间隙。同样,分析了患者年龄与牙齿类型和修复之间的关系,以及开裂线,裂缝,不透明牙本质和间隙的存在。结果本组共168例患者行根尖周手术,手术牙177个,牙根206个。未处理的根管14例(6.8%)。峡部分布在74根(35.9%),特别是在下第一磨牙的近中根(94.1%)。依次,8.3%的根有裂纹,3.9%的根有裂缝,53.4%的根有缝隙。不透明牙本质的患病率为78.3%,其中后牙(前磨牙90.3%,磨牙86.2%)高于前牙(50.6%)(p<0.001)。患者年龄和牙齿修复与研究参数无相关性。结论牙本质不透明的牙本质在73%的牙根(尤其是后牙)中发现,但在不到10%的牙根中发现了裂纹线和裂纹线,超过一半的根管中发现了间隙。关键词:内窥镜,裂纹,间隙,不透明牙本质,根尖周手术。
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引用次数: 1
Influence of root width and dentin wall thickness evaluated by endoscopy upon the outcome of periapical surgery. A cohort study 内窥镜评估牙根宽度和牙本质壁厚对根尖周围手术结果的影响。队列研究
Pub Date : 2022-06-05 DOI: 10.4317/medoral.25314
Pablo Glera-Suarez, Antonio Pallarés-Serrano, David Soto-Peñaloza, Beatriz Tarazona-Álvarez, M. Peñarrocha-Diago, D. Peñarrocha-Oltra
Background An analysis was made of the correlation between root width, the thickness of the remaining dentinal wall as determined by endoscopy, and the outcome of periapical surgery. Material and Methods A retrospective cohort study was carried out involving patients subjected to periapical surgery between 2017 and 2019 at the University of Valencia (Valencia, Spain). One year after surgery, cone-beam computed tomography (CBCT) was used to evaluate healing against the preoperative volumes. The maximum root width was measured on the postoperative CBCT scan at the apical section of the treated root. This measurement was transferred to the intraoperative endoscopic image, where the minimum root width, peripheral dentin thickness, and minimum dentin thickness were recorded. Root measurements, and the position (maxillary or mandibular) and type of tooth (roots of incisors, canines, premolars or molars) were further correlated to periapical surgery outcome. Results A total of 51 patients, comprising 52 teeth and 62 roots, were included in the study. The mean measurements were: maximum root width (4.13±0.84 mm), minimum root width (2.46±0.72 mm), peripheral dentin thickness (0.77±0.2 mm) and minimum dentin thickness (0.4±0.2 mm). The success rate was 82.2%. Premolar roots showed a greater minimum dentin thickness (0.58±0.25 mm) (p<0.003) than incisor roots. No significant association was found between the different measurements and the healing rate at one year, though the roots that failed to heal showed smaller minimum dentin thickness values than the roots that healed correctly. The position and type of tooth did not influence healing outcome. Conclusions The root width and thickness of the remaining dentin wall did not significantly influence healing. However, the roots that failed to heal showed smaller minimum dentin thickness values than the roots that healed correctly. Key words:Endodontic surgery, endoscope, dentin walls.
本研究分析了根宽、内窥镜测定的剩余牙本质壁厚度与根尖周手术结果的相关性。材料与方法回顾性队列研究纳入2017年至2019年在西班牙瓦伦西亚大学(University of Valencia, Spain)接受根尖周围手术的患者。手术后一年,锥形束计算机断层扫描(CBCT)用于评估愈合与术前体积。术后CBCT扫描在治疗根的根尖部分测量最大根宽。测量结果被转移到术中内镜图像中,记录最小牙根宽度、外周牙本质厚度和最小牙本质厚度。牙根测量、位置(上颌或下颌)和牙齿类型(门牙根、犬牙根、前磨牙根或磨牙根)与根尖周手术结果进一步相关。结果共纳入51例患者,包括52颗牙和62根。平均测量值为:最大根宽(4.13±0.84 mm)、最小根宽(2.46±0.72 mm)、外周牙本质厚度(0.77±0.2 mm)和最小牙本质厚度(0.4±0.2 mm)。成功率为82.2%。前磨牙根最小牙本质厚度(0.58±0.25 mm)大于切牙根(p<0.003)。不同的测量值与一年的愈合率之间没有明显的联系,尽管愈合失败的根比愈合正确的根显示出更小的牙本质最小厚度值。牙齿的位置和类型对愈合结果没有影响。结论牙根宽度和剩余牙本质壁厚度对牙本质愈合无显著影响。然而,未愈合的牙根的最小牙本质厚度值比愈合正确的牙根小。关键词:牙髓外科,内窥镜,牙本质壁。
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引用次数: 2
IL-10 and TGF-β1 gene polymorphisms in Greek patients with recurrent aphthous stomatitis 希腊复发性口腔炎患者IL-10和TGF-β1基因多态性
Pub Date : 2022-06-05 DOI: 10.4317/medoral.25352
Vasileios Kounoupis, D. Andreadis, Maria Georgaki, E. Albanidou-Farmaki, M. Daniilidis, A. Markopoulos, N. Karyotis, N. Nikitakis, A. Poulopoulos
Background Recurrent aphthous stomatitis (RAS) is one of the most frequent inflammatory disorders of the oral mucosa. Cytokines, which play an important role in RAS pathogenesis, participate directly or indirectly in normal, immunological and inflammatory processes and are secreted from cells belonging to innate and adaptive immunity as a consequence of microbial and antigenic stimuli. Gene polymorphisms in specific cytokines may predispose to RAS development. The aim of this study was the investigation and association of IL-10 and TGF-β1 gene polymorphisms with RAS. Material and Methods Study’s cohort consisted of 60 Greek patients diagnosed with RAS, including 40 patients with minor, 10 patients with major and 10 with herpetiform aphthous ulcers. Forty age- and sex-matched control subjects were included in this study. DNA was extracted from whole blood samples of all patients and sequence-specific primers (SSP)-based polymerase chain reaction (PCR) was used for genotyping. Gene polymorphisms for cytokines IL-10 at loci -592 and -819 and for TGF-β1 at codon 10 were detected. Results Significant differences between patients with minor RAS and healthy controls were recorded for IL-10 genotypes distribution at position -592 (p=0.042) and -819 (p=0.045) with predominance of C/A and C/T genotypes in RAS patients, respectively. Also, in patients with minor and herpetiform aphthous ulcerations, heterozygous TGF-β1 genotype C/T at codon 10 was associated with increased risk of RAS (p=0.044 and p=0.020, respectively). Conclusions These data provide evidence that genetic predisposition for RAS and possibly its specific clinical variants is related with the presence of gene polymorphisms for specific cytokines, including IL-10 and TGF-β1, which, in turn, may vary according to geographic origin and genetic background. Key words:Recurrent aphthous stomatitis, aphthae, IL-10, TGF-β, gene polymorphisms, oral mucosa.
背景复发性口疮性口炎(RAS)是口腔黏膜最常见的炎症性疾病之一。细胞因子在RAS发病机制中发挥重要作用,直接或间接参与正常、免疫和炎症过程,是先天免疫和适应性免疫细胞在微生物和抗原刺激下分泌的结果。特定细胞因子的基因多态性可能易导致RAS的发生。本研究的目的是研究IL-10和TGF-β1基因多态性与RAS的关系。材料与方法研究的队列包括60名被诊断为RAS的希腊患者,其中40例为轻度,10例为重度,10例为疱疹样阿弗顿溃疡。本研究包括40名年龄和性别匹配的对照受试者。从所有患者的全血样本中提取DNA,采用基于序列特异性引物(SSP)的聚合酶链反应(PCR)进行基因分型。检测到细胞因子IL-10 -592和-819位点和TGF-β1密码子10位点的基因多态性。结果轻度RAS患者IL-10基因型分布在-592位点(p=0.042)和-819位点(p=0.045), RAS患者IL-10基因型分别以C/A和C/T基因型为主。此外,在轻度和疱疹型阿弗特溃疡患者中,密码子10杂合的TGF-β1基因型C/T与RAS风险增加相关(p=0.044和p=0.020)。结论RAS的遗传易感性及其可能的特异性临床变异与IL-10、TGF-β1等特异性细胞因子基因多态性的存在有关,而这些基因多态性又可能因地理来源和遗传背景而异。关键词:复发性口腔炎,口腔溃疡,IL-10, TGF-β,基因多态性,口腔黏膜
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引用次数: 2
Actinic cheilitis: Proposal of a clinical index 光化性唇炎:临床指标的建议
Pub Date : 2022-06-05 DOI: 10.4317/medoral.25243
C. K. Medeiros, M. Lopes, É. D. da Silveira, K. Lima, P. T. de Oliveira
Background Actinic cheilitis is a potentially malignant lesion most commonly found in the lower lip of individuals with chronic exposure to ultraviolet radiation. The aim of this study was to develop and to test a clinical index that can be used to assess the severity of actinic cheilitis. Material and Methods The clinical index of actinic cheilitis was applied to 36 patients. An incisional biopsy was obtained to grade oral epithelial dysplasias following the World Health Organization (WHO) and binary systems, and to evaluate their association with clinical characteristics by Fisher’s exact test (P<0.05). The accuracy of the index was evaluated based on sensitivity, specificity, positive and negative predictive values, and receiver operating curve. Results The blurring between the border of the lip and the skin was significantly associated with cases without dysplasia/mild epithelial dysplasia (P=0.041) and with low risk of malignancy (P=0.005). Ulcers and crusts were significantly associated with moderate/severe epithelial dysplasia (P=0.002 and P=0.012, respectively) and high risk of malignancy (P=0.005 and P=0.045, respectively). Erosion showed a significant association only with high-risk cases of malignancy (P=0.024). The cut-off values of the diagnostic test showing the best performance were 10 for the WHO grading system and 11 for the binary system. Conclusions The index cut-offs with the highest accuracy were considered indicators for a biopsy. Erosion, ulceration and crusts were associated with more severe oral epithelial dysplasias. Key words:Actinic cheilitis, solar cheilosis, lip, precancerous conditions, oral diagnosis, epitelial dysplasia.
光化性唇炎是一种潜在的恶性病变,最常见于长期暴露于紫外线辐射的个体的下唇。本研究的目的是开发和测试一种临床指标,可用于评估光化性唇炎的严重程度。材料与方法应用光化性唇炎的临床指标对36例患者进行分析。根据世界卫生组织(WHO)和二元系统进行口腔上皮发育不良的切口活检分级,并通过Fisher精确检验评估其与临床特征的相关性(P<0.05)。根据敏感性、特异性、阳性预测值和阴性预测值以及受试者工作曲线评价该指标的准确性。结果唇皮边缘模糊与未发育不良/轻度上皮发育不良(P=0.041)、恶性肿瘤风险低(P=0.005)相关。溃疡和结痂与中度/重度上皮发育不良(P=0.002和P=0.012)和恶性肿瘤高风险(P=0.005和P=0.045)显著相关。糜烂仅与高危恶性肿瘤有显著相关性(P=0.024)。显示最佳性能的诊断试验的临界值对于世卫组织分级系统为10,对于二元系统为11。结论准确度最高的指标截断值可作为活检的指标。糜烂、溃疡和结痂与更严重的口腔上皮发育不良有关。关键词:光化性唇裂,太阳唇裂,唇部,癌前病变,口腔诊断,上皮发育不良。
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引用次数: 1
Ameloblastomas mimicking apical periodontitis: a case series 模拟根尖牙周炎的成釉细胞瘤:一个病例系列
Pub Date : 2022-06-05 DOI: 10.4317/medoral.25338
Giuliana Soimu, J. Netto, Á. Miranda, D. Perez, L. Armada, F. Pires
Background Ameloblastomas are benign odontogenic tumors that can eventually mimic the clinical and radiological features of apical periodontitis. The aim of the present study was to evaluate the clinical, radiological and histological characteristics from a series of ameloblastomas mimicking apical periodontitis diagnosed in a 14-year period. Material and Methods all cases histologically diagnosed as ameloblastomas from 2005 to 2018 presenting a clinical diagnosis of periapical lesion of endodontic origin were selected for the study. Clinical, radiological and histological characteristics from all cases were tabulated and descriptively and comparatively analyzed. Results Twenty cases composed the final sample, including 18 solid and 2 unicystic ameloblastomas. Mean age of the affected patients was in the fifth decade with predilection for males (72%). The most common anatomical location was the posterior mandible (55%) and most cases presented a radiolucent unilocular (80%) well-defined (95%) image. Most cases were asymptomatic, but the presence of local swelling and bone cortical rupture were common. Conclusions Ameloblastomas mimicking periapical lesions of endodontic origin are mostly diagnosed in adult males as well-defined radiolucent unilocular lesions producing local swelling and bone cortical rupture. Key words:Ameloblastoma, apical periodontitis, cyst, differencial diagnosis, granuloma, periapical lesion.
成釉细胞瘤是一种良性牙源性肿瘤,其临床和放射学特征最终与根尖牙周炎相似。本研究的目的是评估临床,影像学和组织学特征,从一系列的成釉细胞瘤模拟根尖牙周炎诊断在14年期间。材料与方法本研究选择2005 ~ 2018年组织学诊断为成釉细胞瘤,临床诊断为根管源性根尖周病变的病例。将所有病例的临床、放射学和组织学特征制成表格,进行描述和比较分析。结果最终标本共20例,其中实性成釉细胞瘤18例,单囊性成釉细胞瘤2例。受影响患者的平均年龄在50岁左右,男性居多(72%)。最常见的解剖位置是后下颌骨(55%),大多数病例呈现透光的单眼图像(80%),清晰的图像(95%)。大多数病例无症状,但存在局部肿胀和骨皮质破裂是常见的。结论成釉细胞瘤与根管起源的根尖周围病变相似,在成年男性中多被诊断为界限分明、透光的单眼病变,并伴有局部肿胀和骨皮质破裂。关键词:成釉细胞瘤,根尖牙周炎,囊肿,鉴别诊断,肉芽肿,根尖周围病变。
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引用次数: 0
Validity and reliability of the Turkish version of the orthognathic quality of life questionnaire in patients with dentofacial deformity 土耳其版牙面畸形患者正颌生活质量问卷的效度和信度
Pub Date : 2022-06-05 DOI: 10.4317/medoral.25276
Duygu Turna, M. Benlidayi, Ayça Üstdal Güney, Y. Sertdemir
Background Due to the lack of a specific quality of life (QoL) survey on dentofacial deformities (DFD) for Turkish speakers, the present research aimed to perform a translation of the English version of the Orthognathic Quality of Life Questionnaire (OQLQ) into Turkish (the OQLQ-TR) and provide cultural adaptation to the Turkish population. Material and Methods The process of this cross-cultural adaptation followed the six stages given in the guidelines that were proposed by Beaton et al. (2000), which comprised the following: 1) performing the initial translation, 2) synthesizing the translation, 3) performing the back translation, 4) presenting it to the expert committee, and 5) testing the prefinal version. Throughout the process of validating the Turkish version, the results of the OQLQ were compared with the Oral Health Impact Scale-14 (OHIP-14) and Short Form-36 (SF-36) questionnaires and the Visual Analogue Scale (VAS), which were previously validated in Turkish. All of these Turkish questionnaires (OHIP-14, SF-36, OQLQ) were applied to 69 patients at the Çukurova University Faculty of Dentistry. Results Analysis of the internal consistency of the OQLQ-TR exhibited good correlations for the domains. Moreover, the test-retest reliability also exhibited intra-class correlation coefficients that were excellent. The correlation between the OQLQ-TR and SF-36 was weak and negative. The OQLQ-TR exhibited good correlations with the OHIP-14 and VAS. Conclusions The OQLQ-TR was found to be valid, reliable, and reproducible. Thus, it has become a useful instrument for assessing the quality of life of Turkish-speaking patients with dentofacial deformity. Key words:Dentofacial deformity, orthognathic quality of life, quality of life (QoL), orthognathic surgery.
由于缺乏针对土耳其语使用者的牙面畸形(DFD)的具体生活质量(QoL)调查,本研究旨在将英语版的正颌生活质量问卷(OQLQ)翻译成土耳其语(OQLQ - tr),并为土耳其人口提供文化适应。这种跨文化改编的过程遵循Beaton等人(2000)提出的指导方针中给出的六个阶段,其中包括以下几个阶段:1)进行初始翻译,2)综合翻译,3)进行回译,4)向专家委员会提交,5)测试预定稿。在验证土耳其语版本的整个过程中,将OQLQ的结果与先前用土耳其语验证的口腔健康影响量表-14 (OHIP-14)和简短表格-36 (SF-36)问卷以及视觉模拟量表(VAS)进行比较。所有这些土耳其问卷(OHIP-14, SF-36, OQLQ)应用于Çukurova大学牙科学院的69名患者。结果OQLQ-TR的内部一致性分析显示,各域具有良好的相关性。此外,重测信度也表现出优异的类内相关系数。OQLQ-TR与SF-36呈弱负相关。OQLQ-TR与OHIP-14、VAS有较好的相关性。结论OQLQ-TR方法有效、可靠、可重复性好。因此,它已成为一个有用的工具评估生活质量的土耳其语患者牙面畸形。关键词:牙面畸形,正颌生活质量,生活质量,正颌手术
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引用次数: 1
The impact of COVID-19 on the practice of Oral and Maxillofacial Pathology in the United States and Canada COVID-19对美国和加拿大口腔颌面病理学实践的影响
Pub Date : 2022-04-14 DOI: 10.4317/medoral.25382
V. S. Mutalik, Jasbir D. Upadhyaya, M. Le, D. Schönwetter
Background The COVID-19 pandemic has significantly disrupted the delivery of healthcare, including oral healthcare services. The restrictions imposed for mitigating spread of the virus forced dental practitioners to adopt significant changes in their workflow pattern. The aim of this study was to investigate the impact of the pandemic on the practice of oral and maxillofacial pathology in two countries in regard to educational activities, and clinical and diagnostic pathology services. Material and Methods An online questionnaire was distributed to oral and maxillofacial pathologists in the United States and Canada. The survey was designed by combining dichotomous, multiple choice, and Likert response scale questions. Statistical analysis of the collected data was performed with SPSS software. Results Most pathologists, at the time of survey completion, were teaching synchronously, primarily with case-based learning and live lectures. During lockdown, 52.4% and 50.0% of those with trainees expected their residents to show up for clinic- and laboratory-related procedures respectively. The pathologists were most concerned for their residents’ inadequate clinical exposure, future placement, and face-to-face teaching time. About 89.0% pathologists were able to provide emergent care, with 82.4% and 23.5% having performed telehealth consultations and oral biopsy procedures, respectively. During the lockdown, the pathology laboratories for 90.9% of participants received biopsy specimens that predominantly comprised of potentially malignant or malignant lesions. However, a reduction in the number of biopsy submissions was reported. Conclusions Given the challenges of the pandemic, oral and maxillofacial pathologists in the United States and Canada successfully continued their pursuits in education, clinical care, and diagnostic pathology services. Key words:COVID-19, digital pathology, oral and maxillofacial pathologists, pandemic, telehealth.
2019冠状病毒病大流行严重扰乱了卫生保健服务的提供,包括口腔卫生服务。为减轻病毒传播而施加的限制迫使牙科医生对其工作流程模式进行重大更改。本研究的目的是调查大流行对两个国家口腔颌面病理学实践的影响,包括教育活动、临床和诊断病理学服务。材料与方法对美国和加拿大的口腔颌面病理学家进行在线问卷调查。该调查的设计结合了二分法、多项选择和李克特反应量表问题。采用SPSS软件对收集的数据进行统计分析。结果在调查完成时,大多数病理学家的教学是同步的,主要是基于案例的学习和现场讲座。在封锁期间,52.4%和50.0%的实习生分别希望他们的住院医生出现在诊所和实验室相关程序中。病理学家最关心的是住院医师的临床接触不足、未来的安置和面对面的教学时间。约89.0%的病理学家能够提供紧急护理,其中82.4%和23.5%的病理学家分别进行过远程医疗咨询和口腔活检。在封锁期间,90.9%的参与者的病理实验室收到了主要由潜在恶性或恶性病变组成的活检标本。然而,报告的活检提交数量有所减少。面对疫情的挑战,美国和加拿大的口腔颌面病理学家成功地继续了他们在教育、临床护理和诊断病理学服务方面的追求。关键词:COVID-19,数字病理学,口腔颌面病理学家,大流行,远程医疗
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引用次数: 0
Complications associated with submental liposuction: a scoping review 颏下吸脂术的并发症:一项范围审查
Pub Date : 2022-04-14 DOI: 10.4317/medoral.25122
Demóstenes Alves Diniz, K. Gonçalves, C. G. Silva, Emerllyn Shayane Martins de Araújo, S. Carneiro, Carlos Augusto Pereira do Lago, B. Vasconcelos
Background Liposuction is one of the most commonly performed cosmetic procedures worldwide. Complications associated with submental liposuction are rare. However, when they occur they are significant and can cause disFiguring consequences. The objective of this study was evaluated complications from submentual liposuction in literature and description of clinical experience of complication after submentual liposuction. Material and Methods At first, a scoping review was carried out online search with no time restrictions for complications after submental liposuction was performed in the databases Medline / PubMed, Embase, and Web of Science. The variables analyzed were: age, sex, type of esthetic procedure, anesthesia, complications, time after Procedure, treatment, follow-up care, and sequelae. Then, a case of a patient with submental hematoma after an aesthetic procedure for submental liposuction was described. Results Firstly, 539 articles were selected, after application of the inclusion criteria, 4 studies were included. Most cases were female (8:1), with a mean age of 55.77 years. Postoperative complications were found, such as submental depression, submental edema, hypertrophic scar formation, scar contracture, cervical necrotizing fasciitis, Cervico-facial dystonia and transient facial nerve paralysis. The follow-up period for cases ranged from 3 to 12 months. The clinical case presented there was no sequelae. Conclusions Submental liposuction requires the surgeon's attention. Anatomical knowledge, correct clinical and surgical management, diagnosis, and immediate approach to adverse situations are points that must be respected in this type of esthetic procedure to avoid more serious complications. Key words:Surgery plastic, lipectomy, postoperative complications, hematoma.
吸脂术是世界范围内最常用的美容手术之一。与颏下吸脂相关的并发症是罕见的。然而,当它们发生时,它们是严重的,并可能导致毁容的后果。本研究的目的是评估文献中颏下吸脂术的并发症,并描述颏下吸脂术后并发症的临床经验。材料和方法首先,在Medline / PubMed、Embase和Web of Science数据库中对颏下吸脂术后并发症进行无时间限制的在线搜索,进行范围审查。分析的变量包括:年龄、性别、美容手术类型、麻醉、并发症、手术后时间、治疗、随访护理和后遗症。然后,一个病例的病人与精神下血肿后的审美程序为精神下吸脂被描述。结果首先选取539篇文献,应用纳入标准,最终纳入4篇研究。以女性居多(8:1),平均年龄55.77岁。术后出现颏下凹陷、颏下水肿、增生性瘢痕形成、瘢痕挛缩、颈部坏死性筋膜炎、颈面肌张力障碍、一过性面神经麻痹等并发症。病例随访时间为3至12个月。本病例临床表现无后遗症。结论颏下吸脂术需引起外科医生的重视。解剖知识,正确的临床和手术处理,诊断和对不良情况的及时处理是在这种美容手术中必须尊重的要点,以避免更严重的并发症。关键词:外科整形,唇部切除术,术后并发症,血肿。
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引用次数: 3
Odontogenic tumors: A Retrospective Study in Egyptian population using WHO 2017 classification 牙源性肿瘤:使用世卫组织2017年分类的埃及人群回顾性研究
Pub Date : 2022-04-14 DOI: 10.4317/medoral.24661
L. Al-aroomy, M. Wali, Mohamed Alwadeai, E. Desouky, Hatem Amer
Background Odontogenic tumors (OTs) are considered important among oral lesions because of their clinicopathological heterogeneity and variable biological behavior. The purpose of this retrospective cross-sectional study was to evaluate the frequency and distribution of different types of odontogenic tumors based on the current 2017 WHO Classification of Head and Neck Tumors over a period of 5 years. This was achieved by reviewing the records of Cairo's educational hospitals and institutions and comparing the results with findings in the literature. Material and Methods The records of patients diagnosed with odontogenic tumors were obtained from six educational hospitals and a single institute in Cairo which included: Oral and Maxillofacial Pathology Department, Faculty of Dentistry, Cairo University; General Pathology Department, Faculty of Medicine, Cairo University; Oral Pathology Department, Faculty of Dentistry, Ain Shams University; Eldemerdash Hospital, Ain Shams University; El-Sayed Galal Hospital, Al-Azhar University; Ahmed Maher Teaching Hospital and National Cancer Institute. These records were reviewed over a 5-year (2014-2018) period and the odontogenic tumors were investigated for frequency, age, gender and site. The data were recorded, then analyzed using SPSS software. Results Intraosseous (central) odontogenic tumors constituted 2.56% of all 8974 registered oral and maxillofacial biopsies. A total of 230 cases of OTs were collected and reviewed. Of these, 97.8% were benign and 2.17% were malignant. The mandible was the most commonly affected anatomic location. Ameloblastoma, with a predilection for the posterior mandible, was the most frequent odontogenic tumor (55.65%), followed by cemento-ossifying fibroma (14.78%) and odontoma (9.13%). Females were more commonly affected than males. Most of the patients were in the third and fourth decades of life. There were no peripheral odontogenic tumors diagnosed in this period. Conclusions Some similarities and differences between our findings and those of previous studies of various populations were witnessed. OTs may greatly diverge according to the version of the classification used and by the sample size of the study. Retrospective analysis of the relative frequency of OTs in different countries will be helpful in enhancing the understanding of OTs, which is important for both oral maxillofacial surgeons and pathologists. Key words:Odontogenic tumors, epidemiology, world health organization classification, oral pathology.
牙源性肿瘤(OTs)因其临床病理异质性和多变的生物学行为而被认为是口腔病变中重要的一类。本回顾性横断面研究的目的是基于现行的2017年世卫组织头颈部肿瘤分类,在5年的时间内评估不同类型牙源性肿瘤的频率和分布。这是通过审查开罗教育医院和机构的记录并将结果与文献中的发现进行比较来实现的。材料和方法从开罗的6所教育医院和1所研究所获得诊断为牙源性肿瘤的患者记录,其中包括:开罗大学牙科学院口腔颌面病理学科;开罗大学医学院普通病理学系;英国艾因沙姆斯大学口腔医学院口腔病理学系;艾因沙姆斯大学Eldemerdash医院;爱资哈尔大学El-Sayed Galal医院;艾哈迈德·马赫教学医院和国家癌症研究所。对这些记录进行了5年(2014-2018年)的回顾,并调查了牙源性肿瘤的频率、年龄、性别和部位。对数据进行记录,并用SPSS软件进行分析。结果8974例口腔颌面部活检中,骨内(中央)牙源性肿瘤占2.56%。共收集和审查了230例门诊病例。其中良性97.8%,恶性2.17%。下颌骨是最常受影响的解剖部位。成釉细胞瘤是最常见的牙源性肿瘤(55.65%),其次是骨水泥骨化纤维瘤(14.78%)和牙髓瘤(9.13%)。女性比男性更容易受到影响。大多数患者处于生命的第三和第四十年。这一时期未发现外周牙源性肿瘤。结论本研究结果与以往不同人群的研究结果有一定的异同。根据所使用的分类版本和研究的样本量,OTs可能会有很大的差异。回顾性分析不同国家外伤性喉炎的相对发生率,有助于加深对外伤性喉炎的认识,这对口腔颌面外科医生和病理学家都有重要意义。关键词:牙源性肿瘤;流行病学;世界卫生组织分类;
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引用次数: 3
Medication related to pigmentation of oral mucosa 与口腔黏膜色素沉着有关的药物
Pub Date : 2022-04-14 DOI: 10.4317/medoral.25110
María del Carmen Mallagray-Montero, L. Moreno-López, R. Cerero-Lapiedra, María Castro-Janeiro, Cristina Madrigal-Martínez-Pereda
Background The diagnosis of oral melanotic lesions is, more often than not, challenging in the clinical practice due to the fact that there are several reasons which may cause an increase in pigmentation on localized or generalized areas. Among these, medication stands out. Material and Methods In this work, we have carried out a review in the reference pharma database: Micromedex® followed by a review of the scientific published literature to analyse coincidences and possible discrepancies. Results Our findings show that there are several prescription drugs that can cause pigmented lesions in the oral mucosa. This must be known by clinicians in order to properly diagnose pigmented lesions. We have identified a set of 21 medicaments which cause these lesions, some of which are used frequently in the clinic, such as Metronidazole, Amitriptyline, conjugated oestrogens and Chlorhexidine gluconate. We also found discrepancies with the data published in specialized literature, some of which wasn’t reflected in the Summary of Product Characteristics. Conclusions Our work highlights the importance of the proper communication of adverse drug reactions (ADR) by health professionals in order to provide thorough and accurate information and diagnosis. Key words:Adverse drug reactions, oral pigmentation, micromedex.
背景口腔黑色素病变的诊断在临床实践中往往具有挑战性,因为有几个原因可能导致局部或全身区域色素沉着增加。其中,药物治疗尤为突出。材料和方法在这项工作中,我们在参考制药数据库Micromedex®中进行了回顾,然后对科学发表的文献进行了回顾,以分析巧合和可能的差异。结果多种处方药物均可引起口腔黏膜色素病变。临床医生必须了解这一点,以便正确诊断色素病变。我们已经确定了21种导致这些病变的药物,其中一些在临床上经常使用,如甲硝唑、阿米替林、偶联雌激素和葡萄糖酸氯己定。我们还发现与专业文献中发表的数据存在差异,其中一些没有反映在产品特性摘要中。结论:我们的工作强调了卫生专业人员正确沟通药物不良反应(ADR)的重要性,以便提供全面准确的信息和诊断。关键词:药物不良反应,口腔色素沉着,微美度。
{"title":"Medication related to pigmentation of oral mucosa","authors":"María del Carmen Mallagray-Montero, L. Moreno-López, R. Cerero-Lapiedra, María Castro-Janeiro, Cristina Madrigal-Martínez-Pereda","doi":"10.4317/medoral.25110","DOIUrl":"https://doi.org/10.4317/medoral.25110","url":null,"abstract":"Background The diagnosis of oral melanotic lesions is, more often than not, challenging in the clinical practice due to the fact that there are several reasons which may cause an increase in pigmentation on localized or generalized areas. Among these, medication stands out. Material and Methods In this work, we have carried out a review in the reference pharma database: Micromedex® followed by a review of the scientific published literature to analyse coincidences and possible discrepancies. Results Our findings show that there are several prescription drugs that can cause pigmented lesions in the oral mucosa. This must be known by clinicians in order to properly diagnose pigmented lesions. We have identified a set of 21 medicaments which cause these lesions, some of which are used frequently in the clinic, such as Metronidazole, Amitriptyline, conjugated oestrogens and Chlorhexidine gluconate. We also found discrepancies with the data published in specialized literature, some of which wasn’t reflected in the Summary of Product Characteristics. Conclusions Our work highlights the importance of the proper communication of adverse drug reactions (ADR) by health professionals in order to provide thorough and accurate information and diagnosis. Key words:Adverse drug reactions, oral pigmentation, micromedex.","PeriodicalId":18367,"journal":{"name":"Medicina Oral, Patología Oral y Cirugía Bucal","volume":"29 4","pages":"e230 - e237"},"PeriodicalIF":0.0,"publicationDate":"2022-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72595940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
期刊
Medicina Oral, Patología Oral y Cirugía Bucal
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