俄罗斯第三波和第四波COVID-19流行的主要病原体SARS-CoV-2病毒的δ型变异特征

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引用次数: 1

摘要

在SARS-CoV-2病毒的流行变体中,目前引起主要关注的是delta变体(B.1.617),该变体于2020年底在印度首次发现。自delta型变异出现以来,印度的COVID-19发病率增加了20倍。SARS-CoV-2病毒的δ型变体在印度以外的泛滥是第三波COVID-19大流行出现的因素之一。截至2021年8月24日,已在193个国家发现了SARS-CoV-2病毒的δ型变体。本研究的目的是分析SARS-CoV-2病毒的δ型变异及其引起的疾病特征。delta型变异的主要特征是:一系列影响s蛋白重要功能区的突变;转换率:人与人之间的转换率;潜伏期被引起的疾病的较短的潜伏期在俄罗斯,SARS-CoV-2病毒的δ型变异不早于2021年4月底至5月初出现。作为占主导地位的delta型病毒变体的传播与2021年6月初第三波和9月中旬俄罗斯出现的第四波COVID-19流行有关。俄罗斯的流行病学数据显示,该疾病的新病例数量急剧增加,同时住院人数和死亡人数也在增加。防治这一流行病的必要措施是:首先,加快疫苗接种的步伐,以及一整套行政措施,包括限制大规模事件、严格遵守戴口罩制度和在公共场所保持社交距离
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The Characteristics of the Delta Variant of SARS-CoV-2 Virus – the Dominant Agent of the Third and Forth Waves of Epidemic COVID-19 in Russia
Among the epidemic variants of the SARS-CoV-2 virus the main attention is currently attracted by the delta variant (B.1.617), first identified in India in the end of 2020. Since the appearance of the delta variant, the morbidity rate of COVID-19 in India has increased 20-fold. The overflow of the delta variant of the SARS-CoV-2 virus outside of India is one of the factors in the emergence of the third wave of the COVID-19 pandemic. As of August 24, 2021 the delta variant of SARS-CoV-2 virus has been identified in 193 countries. The purpose of this work is to analyze the delta variant of SARS- CoV-2 virus and the features of the disease caused by it. The main features of the delta variant are: a set of mutations affecting a significant functional area of S-protein; a transfer rate from person to person; a reduced incubation period of caused disease. In Russia, the delta variant of SARS-CoV-2 virus appears no earlier than the end of April – beginning of May, 2021. The spread of the delta variant as the dominant one is associated with the emergence in early June 2021 of the third, and in mid-September – the fourth wave of the COVID-19 epidemic in Russia. The epidemiological data for Russia show a sharp increase in the number of new cases of the disease, with a simultaneous increase in the number of hospitalizations and deaths of the disease. The necessary measures to combat the epidemic are: first of all, accelerating the pace of vaccination, as well as the set of administrative measures, including limiting mass events, strict observance of the mask regime and social distance in public places
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