{"title":"甲状腺激素在男性生殖和生育中的作用","authors":"Rajender Singh, A. Hamada, A. Agarwal","doi":"10.2174/1874255601103010098","DOIUrl":null,"url":null,"abstract":"Thyroid hormones, previously thought not to affect spermatogenesis and male fertility, are now being recognized as having important role in spermatogenesis. The identification of thyroid hormone receptors on Sertoli cells, the nurturing cells for sperm in the testis, has embarked further research to investigate the role of thyroid hormones in male reproduction. Since spermatogenesis occurs in close contact with the Sertoli cells, the thyroid hormones must exert significant regulatory role in sperm production. Therefore, disturbances in the thyroid function could affect spermatogenesis and male fertility. Studies on human subjects and animals models are now revealing further insights into the effect of thyroid hormones on male fertility and infertility. The present review provides an update on the role of thyroid hormones in spermatogenesis and male fertility.","PeriodicalId":88757,"journal":{"name":"The open reproductive science journal","volume":"15 1","pages":"98-104"},"PeriodicalIF":0.0000,"publicationDate":"2011-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"67","resultStr":"{\"title\":\"Thyroid Hormones in Male Reproduction and Fertility\",\"authors\":\"Rajender Singh, A. Hamada, A. Agarwal\",\"doi\":\"10.2174/1874255601103010098\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Thyroid hormones, previously thought not to affect spermatogenesis and male fertility, are now being recognized as having important role in spermatogenesis. The identification of thyroid hormone receptors on Sertoli cells, the nurturing cells for sperm in the testis, has embarked further research to investigate the role of thyroid hormones in male reproduction. Since spermatogenesis occurs in close contact with the Sertoli cells, the thyroid hormones must exert significant regulatory role in sperm production. Therefore, disturbances in the thyroid function could affect spermatogenesis and male fertility. Studies on human subjects and animals models are now revealing further insights into the effect of thyroid hormones on male fertility and infertility. The present review provides an update on the role of thyroid hormones in spermatogenesis and male fertility.\",\"PeriodicalId\":88757,\"journal\":{\"name\":\"The open reproductive science journal\",\"volume\":\"15 1\",\"pages\":\"98-104\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2011-09-23\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"67\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The open reproductive science journal\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.2174/1874255601103010098\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The open reproductive science journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2174/1874255601103010098","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Thyroid Hormones in Male Reproduction and Fertility
Thyroid hormones, previously thought not to affect spermatogenesis and male fertility, are now being recognized as having important role in spermatogenesis. The identification of thyroid hormone receptors on Sertoli cells, the nurturing cells for sperm in the testis, has embarked further research to investigate the role of thyroid hormones in male reproduction. Since spermatogenesis occurs in close contact with the Sertoli cells, the thyroid hormones must exert significant regulatory role in sperm production. Therefore, disturbances in the thyroid function could affect spermatogenesis and male fertility. Studies on human subjects and animals models are now revealing further insights into the effect of thyroid hormones on male fertility and infertility. The present review provides an update on the role of thyroid hormones in spermatogenesis and male fertility.
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