A case of verruciform xanthoma of the gingiva on upper jaw. With immunochemical and ultrastructural observation.:with immmochemical and ultrastructural observation

Verruciform xanthoma arising from the gingival mucosa of the upper left first premolar to first molar area of a 59-year-old female is presented. It is a rare lesion of the oral cavity which has a warty or papillary appearance. It was first described by Shafer in 1971 with histopathological characteristics of verruciform growth and proliferation of xanthoma cells in the lamina propia.In Japan Kikuchi et al. reported the first case in 1977. Since then almost 40 cases have so far been published.This article described a case of Verruciform xanthoma together with its light, immunochemical and and electron microscopic fingings. Judging from the immunochemical finding, foamy cells were negative for S-100 protein and positive for lysozyme and NCA (non-specific cross reacting antigen with carcinoembryonic antigen), all of which were suggested that they were derived from monocyte-macrophage cell lines.