Comparación de tasas de embarazo en transferencia embrionaria en pacientes mayores y menores de 40 años

Introduction

Endometrial physiology and embryo quality greatly depend on the age of the patient, thus, the main objective of this study is to measure the pregnancy rates (by human !-Gonadotropin) in women older and younger than 40 years of age.

Materials and methods

A retrospective, case-control study was conducted in which 306 IVF cycles performed on patients between 24 and 58 years of age by conventional In-Vitro Fertilisation or intracytoplasmic sperm injection in the reproductive medicine unit of Hospital Ángeles.

Pedregal in Mexico City between January 2015 and January 2018.

Results

The total population of 306 cycles included 161 patients >40 years and 139 were < 39. In the >40 population, 22.3% had a positive !-fraction, compared to 28.27% in the < 39 population. As for the embryo transfer (ET) day, it was found that an ET in day 5/6 showed the highest pregnancy rates, specifically when compared against day 2 ET in patients under 39 years of age (P = .029).

Conclusions

When comparing embryo transfer day 2 vs. day 5/6, a statistically significant difference was found in the pregnancy rates in patients over 40 and less than 39 years of age.