海胆卵子的精子受体

Kathleen R. Foltz
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引用次数: 16

摘要

海胆卵子的精子受体是第一个存在于卵质膜上的配子识别蛋白的例子,卵质膜是与精子进行最终物种特异性相互作用的地方。这种独特的跨膜糖蛋白的鉴定和表征为配子识别和结合以及卵子活化的分子基础带来了新的问题。本文试图对这些新问题进行界定和讨论,并指出并开始解决受精的分子和生物学方面的一些不一致之处。
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The sea urchin egg receptor for sperm

The sea urchin egg receptor for sperm represents the first example of a gamete recognition protein residing in the egg plasma membrane, the site of the final species-specific interaction with the sperm. The identification and characterization of this unique transmembrane glycoprotein have led to new questions about the molecular basis of gamete recognition and binding as well as egg activation. This review attempts to define and discuss some of these new questions and to point out and begin to resolve several inconsistencies between the molecular and the biological aspects of fertilization.

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