结合在肠刷边缘的水解酶:跨膜蛋白的一个例子

S. Maroux, D. Louvard, M. Sémériva, P. Desnuelle
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引用次数: 5

摘要

在膜上插入疏水结构域,使头部在表面稳定;(c)穿透细胞质的短节。这种类型的跨膜蛋白可能涉及任何类型的信息从细胞质膜的一边转移到另一边。特别是,由于“头部”的催化活性,源自肽的氨基酸可能直接注入载体体系。这一机制尚未得到实验证实。然而,这将节省能量,并解释了为什么来自腔内肽的氨基酸比游离氨基酸更容易被吸附。
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Hydrolases bound to the intestinal brush border : An example of transmembrane proteins
hydrophobic domain inserted in the membrane, stabilizing the head at the surface ; (c) a short segment penetrating into the cytoplasm. This type of transmembrane proteins could be implicated in the transfer of any kind of information from one side of the cellular plasma membrane to the other. In particular, the amino acids originating from peptides due to the catalytic activity of the « head » might be directly injected into the carrier system. This mechanism has not yet been experimentally confirmed. However, it would economize energy and explain why amino acids originating from peptides in the lumen were better adsorbed than free amino acids.
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