精索静脉曲张手术:三年经验

Süleyman Sağır, Mustafa Azizoglu
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引用次数: 0

摘要

尽管有像精索静脉曲张切除术这样的治疗方法,但标准治疗仍然存在争议。精索静脉曲张修复已显示出改善精子参数的希望,但需要进一步的研究,特别是在非阻塞性无精子症病例中。显微睾丸精子提取和卵胞浆内单精子注射等技术在怀孕方面取得了一些成功。目的:阐明我们对精索静脉曲张的实践经验和理解。方法:本研究纳入了2020年11月至2023年1月期间因精索静脉曲张就诊并接受手术治疗的患者。结果:本研究纳入26例精索静脉曲张患者,主要年龄为27.5岁。大多数(85%)为左侧精索静脉曲张,15%为双侧精索静脉曲张。左侧和双侧静脉平均直径分别为3.58mm和2.6mm,一般平均值为3.45mm。精子数量、活力和形态的分析平均为3260万/ml,分别为23.2%和5.23%。手术中平均有4.45根静脉结扎,根据侧面有轻微的差异。一名患者由于手术并发症失去了大约85%的睾丸血供,导致睾丸硬化但没有萎缩。2例复发(复发率7.6%)。结扎静脉数与术前精子数呈负相关(p=0.043, r=-0.408),静脉直径与术前精子形态呈正相关(p=0.004, r=0.544)。结论:尽管存在局限性,但我们的研究为精索静脉曲张严重程度与精子参数之间的关系提供了有价值的见解。
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Varicocele Surgery: Three Years Experience
Despite available treatments like varicocelectomy, a standard therapy remains controversial. Varicocele repair has shown promise in improving sperm parameters, but further research is needed, especially in nonobstructive azoospermia cases. Techniques such as microscopic testicular sperm extraction and intracytoplasmic sperm injection have shown some success in achieving pregnancies. Objective: To articulate our hands-on experience and understanding pertaining to varicocele. Methods: This study included patients who presented to our clinic due to varicocele and underwent surgical procedures between November 2020 and January 2023. Results: This research involved 26 varicocele patients, primarily age rage was 27.5 years old. The majority (85%) had varicocele on the left side, and 15% had bilateral varicocele. The mean vein diameter was 3.58mm and 2.6mm for the left side and bilateral cases respectively, with a general average of 3.45mm. Analysis of sperm count, motility, and morphology reflected an average of 32.6 million/ml, 23.2%, and 5.23%, respectively. An average of 4.45 veins was ligated during surgery, with a slight variance based on the side. One patient lost approximately 85% of the testicular blood supply due to a complication during surgery, leading to testicle hardening without atrophy. Two patients experienced recurrence (7.6% recurrence rate). Negative and positive correlations were found between the number of ligated veins and preoperative sperm count (p=0.043, r=-0.408), and vein diameter and preoperative sperm morphology (p=0.004, r=0.544), respectively. Conclusions: Despite the limitations, our study provides valuable insights into the relationship between varicocele severity and sperm parameters.
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