脑池造口术治疗外伤性脑损伤的预后和预测因素——高等医学中心的一项前瞻性观察研究

IF 0.2 Q4 NEUROSCIENCES Indian Journal of Neurotrauma Pub Date : 2022-09-12 DOI:10.1055/s-0041-1739478
R. Vemula, B. Prasad, H. N. Banavath, Pavan Kale, Mohana Murali Krishna N, Sreeram Gokanapudi
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引用次数: 1

摘要

背景外伤性脑损伤(TBI)是年轻人发病和死亡的主要原因。TBI患者的治疗目标主要集中在继发性损伤。由于蓄水池和大脑相互交流,通过打开蓄水池,使其与大气压力保持一致,就有可能降低这两个隔间的压力。目的探讨脑池造口术治疗脑外伤的疗效及预测因素。方法采用单一三级保健中心对术中颅内压(ICP)监测的胆池造口术的预后进行前瞻性观察研究。采用Marshall CT评分对患者进行临床和影像学评价。根据格拉斯哥昏迷量表(GCS)评分将患者分为轻度、中度和重度脑损伤组。采用格拉斯哥结局量表(GOS)评分对结果进行评估。结果共纳入25例TBI患者。他们接受了胆池造口术,术中监测ICP。他们根据年龄分为4组。在我们的研究中,死亡率为32%随访3个月,有48%的患者恢复良好,GOS评分为4和5。胆池造瘘后平均颅内压为6.36±1.91 mm Hg,本研究胆池造瘘后颅内压降低。结论年龄、外伤至手术时间间隔、颅内压对预后有重要影响。脑池造瘘术可有效降低颅内压,减少术后并发症。
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Outcomes and Predictors of Outcome with Cisternostomy in the Management of Traumatic Brain Injury—A Prospective Observational Study at Tertiary Centre
Background Traumatic brain injury (TBI) is a major cause of morbidity and mortality in young individuals. Goal of management in TBI patients is mainly focused on the secondary injury. Since the cisterns and the brain communicate, it would be possible to decrease the pressure in both these compartments by opening the cisterns to the atmospheric pressure. Objective To study the outcomes and predictors of outcome with cisternostomy in the management of TBI. Methods A single tertiary care center's prospective observational study of outcomes with cisternostomy with intraoperative intracranial pressure (ICP) monitoring. Patients were evaluated clinically and radiologically with Marshall CT score. They were categorized into mild, moderate, and severe head injury groups based on Glasgow coma scale (GCS) score. Outcomes were evaluated with Glasgow outcome scale (GOS) score. Results A total of 25 patients with TBI were enrolled in this study. They underwent cisternostomy with intraoperative ICP monitoring. They were categorized into 4 groups based on the age. In our study, mortality rate was 32%. As much as 48% had good recovery at 3 months follow-up with GOS 4 and 5. Mean ICP after cisternostomy was 6.36 ± 1.91 mm Hg. In our study, there was decrease in ICP after cisternostomy. Conclusion Age, time interval from trauma to surgery, and ICP showed prognostic importance on outcomes. Cisternostomy can efficiently decrease the ICP in the TBI patients and reduce postoperative complications.
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