{"title":"红叶的降血脂作用。茎皮对Triton WR-1339和高脂饮食诱导的高脂血症大鼠的影响","authors":"Surendran Surya, Ravindrakurup Arun Kumar, Betty Carla, Christudas Sunil","doi":"10.1016/j.bfopcu.2016.10.003","DOIUrl":null,"url":null,"abstract":"<div><p><em>Ficus dalhousiae</em> stem bark is used to treat cancer and hyperlipidemia in folklore practices. <em>F. dalhousiae</em> stem bark methanolic extract (250 and 500<!--> <!-->mg/kg<!--> <!-->b. wt.) was evaluated for antihyperlipidemic activity in Triton WR-1339 and high fat diet-induced hyperlipidemic rats. <em>F. dalhousiae</em> extract significantly (<em>P</em> <em>⩽</em> <!-->0.005) alter the serum TC, TG, LDL-C and HDL-C levels to near normal in Triton WR-1339 and high fat diet-induced hyperlipidemic rats. The liver total cholesterol and triglycerides were also significantly reduced after treatment with 250 and 500<!--> <!-->mg/kg of <em>F. dalhousiae.</em> The result of this study indicates that <em>F. dalhousiae</em> has a significant potential to use as a natural antihyperlipidemic agent.</p></div>","PeriodicalId":9369,"journal":{"name":"Bulletin of Faculty of Pharmacy, Cairo University","volume":"55 1","pages":"Pages 73-77"},"PeriodicalIF":0.0000,"publicationDate":"2017-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.bfopcu.2016.10.003","citationCount":"18","resultStr":"{\"title\":\"Antihyperlipidemic effect of Ficus dalhousiae miq. stem bark on Triton WR-1339 and high fat diet-induced hyperlipidemic rats\",\"authors\":\"Surendran Surya, Ravindrakurup Arun Kumar, Betty Carla, Christudas Sunil\",\"doi\":\"10.1016/j.bfopcu.2016.10.003\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p><em>Ficus dalhousiae</em> stem bark is used to treat cancer and hyperlipidemia in folklore practices. <em>F. dalhousiae</em> stem bark methanolic extract (250 and 500<!--> <!-->mg/kg<!--> <!-->b. wt.) was evaluated for antihyperlipidemic activity in Triton WR-1339 and high fat diet-induced hyperlipidemic rats. <em>F. dalhousiae</em> extract significantly (<em>P</em> <em>⩽</em> <!-->0.005) alter the serum TC, TG, LDL-C and HDL-C levels to near normal in Triton WR-1339 and high fat diet-induced hyperlipidemic rats. The liver total cholesterol and triglycerides were also significantly reduced after treatment with 250 and 500<!--> <!-->mg/kg of <em>F. dalhousiae.</em> The result of this study indicates that <em>F. dalhousiae</em> has a significant potential to use as a natural antihyperlipidemic agent.</p></div>\",\"PeriodicalId\":9369,\"journal\":{\"name\":\"Bulletin of Faculty of Pharmacy, Cairo University\",\"volume\":\"55 1\",\"pages\":\"Pages 73-77\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2017-06-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/j.bfopcu.2016.10.003\",\"citationCount\":\"18\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Bulletin of Faculty of Pharmacy, Cairo University\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1110093116300357\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bulletin of Faculty of Pharmacy, Cairo University","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1110093116300357","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Antihyperlipidemic effect of Ficus dalhousiae miq. stem bark on Triton WR-1339 and high fat diet-induced hyperlipidemic rats
Ficus dalhousiae stem bark is used to treat cancer and hyperlipidemia in folklore practices. F. dalhousiae stem bark methanolic extract (250 and 500 mg/kg b. wt.) was evaluated for antihyperlipidemic activity in Triton WR-1339 and high fat diet-induced hyperlipidemic rats. F. dalhousiae extract significantly (P⩽ 0.005) alter the serum TC, TG, LDL-C and HDL-C levels to near normal in Triton WR-1339 and high fat diet-induced hyperlipidemic rats. The liver total cholesterol and triglycerides were also significantly reduced after treatment with 250 and 500 mg/kg of F. dalhousiae. The result of this study indicates that F. dalhousiae has a significant potential to use as a natural antihyperlipidemic agent.