{"title":"催产素的多种作用","authors":"Sung Hye Kim, P. Bennett, V. Terzidou","doi":"10.14800/ICS.739","DOIUrl":null,"url":null,"abstract":"The oxytocin/oxytocin receptor (OT/OTR) system has been reported to influence a variety of physiological, behavioural, and emotional processes in humans. There are a wide range of studies focusing on their role in parturition, lactation and behaviour. More recent studies have investigated the novel effects of OT/OTR system including inflammation and miRNAs, as well as the effect of their genetic polymorphisms on the onset of labour and parturition. OT also appears to have a great influence in cardiomyocyte differentiation and heart homeostasis, and an age-specific regulation of muscle maintenance and regeneration. This review will summarize the previously established role of OT/OTR system as well as the studies on their novel roles, and highlight the potential therapeutic approaches.","PeriodicalId":13679,"journal":{"name":"Inflammation and cell signaling","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2015-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Diverse roles of oxytocin\",\"authors\":\"Sung Hye Kim, P. Bennett, V. Terzidou\",\"doi\":\"10.14800/ICS.739\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The oxytocin/oxytocin receptor (OT/OTR) system has been reported to influence a variety of physiological, behavioural, and emotional processes in humans. There are a wide range of studies focusing on their role in parturition, lactation and behaviour. More recent studies have investigated the novel effects of OT/OTR system including inflammation and miRNAs, as well as the effect of their genetic polymorphisms on the onset of labour and parturition. OT also appears to have a great influence in cardiomyocyte differentiation and heart homeostasis, and an age-specific regulation of muscle maintenance and regeneration. This review will summarize the previously established role of OT/OTR system as well as the studies on their novel roles, and highlight the potential therapeutic approaches.\",\"PeriodicalId\":13679,\"journal\":{\"name\":\"Inflammation and cell signaling\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2015-04-19\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Inflammation and cell signaling\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.14800/ICS.739\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Inflammation and cell signaling","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.14800/ICS.739","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
The oxytocin/oxytocin receptor (OT/OTR) system has been reported to influence a variety of physiological, behavioural, and emotional processes in humans. There are a wide range of studies focusing on their role in parturition, lactation and behaviour. More recent studies have investigated the novel effects of OT/OTR system including inflammation and miRNAs, as well as the effect of their genetic polymorphisms on the onset of labour and parturition. OT also appears to have a great influence in cardiomyocyte differentiation and heart homeostasis, and an age-specific regulation of muscle maintenance and regeneration. This review will summarize the previously established role of OT/OTR system as well as the studies on their novel roles, and highlight the potential therapeutic approaches.
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