碳纳米材料的合成及其在电化学传感器发展中的应用,以测定临床感兴趣的药物和化合物

IF 3.6 3区 化学 Q2 CHEMISTRY, ANALYTICAL Reviews in Analytical Chemistry Pub Date : 2019-09-01 DOI:10.1515/revac-2019-0017
L. S. Porto, D. N. Silva, Anabel de Oliveira, A. Pereira, K. Borges
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引用次数: 28

摘要

众所周知,与电化学传感器相关的研究显著增加,因为这些设备具有很好的特性,如获取信息的可能性,所研究系统的操作最少,实时,对环境的影响小。本文介绍了碳纳米材料的主要性质、合成方法,以及这些材料在开发用于临床药物和化合物分析的电化学传感器中的应用。在这种情况下,药物分析对质量控制极其重要,以确保药物有效地发挥其作用,而不会出现可能损害患者健康和生活质量的并发症。此外,能够确定生物液体中临床感兴趣的化合物的分析方法对于有效诊断的指示极为重要。因此,电分析技术的通用性、选择性和便携性使电化学传感器成为测定临床感兴趣的药物和化合物的最受欢迎的工具。在目前的工作中,可以得出碳纳米材料具有优良的导热性和导电性、强吸附能力、高电催化效果、高生物相容性和高表面积等特点。基于碳质纳米材料形成不同复合材料的可能性,使得这些材料有望用于分析传感器的开发,有助于快速,敏感和低成本的分析。
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Carbon nanomaterials: synthesis and applications to development of electrochemical sensors in determination of drugs and compounds of clinical interest
Abstract It is notorious that researches related to electrochemical sensors increased significantly due the promising characteristics that these devices present such as the possibility of obtaining information, with minimum manipulation of the studied system, in real time, and with low environmental impact. This article covers the carbon nanomaterials, presenting important aspects such as main properties, synthesis methods, and the application of these materials in the development of electrochemical sensors for the analysis of drugs and compounds of clinical interest. In this context, drug analysis is extremely important for quality control, to ensure that the medicine fulfills its role effectively without possible complications that could compromise the patient’s health and quality of life. In addition, analytical methods capable of determining compounds of clinical interest in biological fluids are extremely important for the indication of effective diagnoses. Thus, the versatility, selectivity, and portability of the electroanalytical techniques make the electrochemical sensors a favorite tool for the determination of drugs and compounds of clinical interest. It will be possible to follow in the present work that carbon nanomaterials have excellent thermal and electrical conductivity, strong adsorption capacity, high electrocatalytic effect, high biocompatibility, and high surface area. The possibility of formation of different composite materials based on carbonaceous nanomaterials that makes these materials promising for the development of analytical sensors, contributing to rapid, sensitive, and low-cost analyses can also be highlighted.
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来源期刊
Reviews in Analytical Chemistry
Reviews in Analytical Chemistry 化学-分析化学
CiteScore
7.50
自引率
0.00%
发文量
15
审稿时长
>12 weeks
期刊介绍: Reviews in Analytical Chemistry publishes authoritative reviews by leading experts in the dynamic field of chemical analysis. The subjects can encompass all branches of modern analytical chemistry such as spectroscopy, chromatography, mass spectrometry, electrochemistry and trace analysis and their applications to areas such as environmental control, pharmaceutical industry, automation and other relevant areas. Review articles bring the expert up to date in a concise manner and provide researchers an overview of new techniques and methods.
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