Recent problems for the elderly life - diabetes, dementia, frailty

Firstly, diabetes shows decreased insulin secretion from beta cell of pancreas and the presence of insulin resistance. These disorders were expressed as homeostasis model assessment of insulin resistance (HOMA-R) and homeostasis model assessment of β cell function (HOMA-β).1 From the clinical point of view, there is common path physiological mechanism of insulin resistance which is found in diabetes, hypertension, Hyperlipidemia, obesity, metabolic syndrome and so on. Consequently, weight reduction and diet therapy would be necessary.